The effects of acute kidney injury on long-term renal function and proteinuria in a general hospitalised population [0.03%]
急性肾损伤对一般住院人群长期肾功能及蛋白尿的影响
Kerry L Horne,Rebecca Packington,John Monaghan et al.
Kerry L Horne et al.
Background: Acute kidney injury (AKI) is common in hospitalised patients and is associated with adverse long-term consequences. There is an urgent need to understand these sequelae in general hospitalised patients utilisi...
Lower plasma sodium is associated with a microinflammatory state among patients with advanced chronic kidney disease [0.03%]
低血钠与晚期慢性肾脏病患者的微炎症状态相关
Olimpia Ortega,Gabriela Cobo,Isabel Rodríguez et al.
Olimpia Ortega et al.
Background/aims: Lower serum sodium levels have been associated with increased mortality among patients with chronic kidney disease (CKD). Our aim was to analyze the independent factors associated with lower sodium levels...
Observational Study
Nephron. Clinical practice. 2014;128(3-4):312-8. DOI:10.1159/000368116 2014
Hannah Beckwith,Liz Lightstone
Hannah Beckwith
Treatment options for systemic lupus erythematosus (SLE) and lupus nephritis (LN) have high associated morbidity and mortality. Side effects, particularly from long-term corticosteroid usage, limit patient adherence, with subsequent impacts...
Rituximab in primary membranous nephropathy: first-line therapy, why not? [0.03%]
利妥昔单抗治疗原发性膜性肾病：为什么不宜作为一线用药？
Paolo Cravedi,Giuseppe Remuzzi,Piero Ruggenenti
Paolo Cravedi
The ideal treatment of patients with primary membranous nephropathy (MN) and persistent nephrotic syndrome (NS) is still a matter of debate. This is a major issue since these patients may progress to end-stage kidney disease (ESKD) in 5-10 ...
Reena J Popat,Michael G Robson
Reena J Popat
The complement pathway is a central part of the innate immune system and also modulates adaptive immunity. It is implicated in the pathogenesis of glomerular disease by a number of clinical findings. These include the presence of complement...
Limitations of standard immunosuppressive treatment in ANCA-associated vasculitis and lupus nephritis [0.03%]
抗中性粒细胞胞浆抗体相关性血管炎和狼疮肾炎的标准免疫抑制治疗的局限性
Vladimir Tesar,Zdenka Hruskova
Vladimir Tesar
Introduction of the standard immunosuppressive treatment has dramatically changed the outcome of patients with both ANCA-associated vasculitis and lupus nephritis, transforming them from incurable diseases with very high short-term mortalit...
Relationship between HSP70-2 A+1267G Polymorphism and Cardiovascular Events of Chinese Peritoneal Dialysis Patients [0.03%]
中国腹膜透析患者HSP70-2A+1267G多态性与心血管事件的关系
Peter Yam-Kau Poon,Cheuk-Chun Szeto,Bonnie Ching-Ha Kwan et al.
Peter Yam-Kau Poon et al.
Background: Heat shock proteins (HSPs) are expressed by cells in response to various environmental stresses. A single-nucleotide polymorphism A+1267G of the HSPA1B gene affects the expression of HSP70-2, with the A allele...
Population-based estimated reference creatinine values: a novel method of a robust electronic acute kidney injury alert system [0.03%]
基于人群的估计参考肌酐值：一种稳健的电子急性肾损伤警报系统的新方法
Shahed Ahmed,Sarah Curtis,Charlotte Hill et al.
Shahed Ahmed et al.
Background: Acute kidney injury (AKI) is common in hospitalized patients. Despite the progress that has been made in the last decade, early identification of AKI cases remains a challenge. In recent years, electronic AKI ...
Kosaku Nitta,Nobuo Nagano,Ken Tsuchiya
Kosaku Nitta
Fibroblast growth factor-23 (FGF23) is a bone-derived hormone that regulates phosphate and 1,25-hydroxyvitamin D [1,25(OH)2D] metabolism. FGF23 binds to FGF receptor 1 with its coreceptor Klotho and maintains serum phosphate levels within t...
Comparison of different methods of erythrocyte dysmorphism analysis to determine the origin of hematuria [0.03%]
比较不同红细胞形态分析方法在血尿来源鉴别中的应用价值
Marila Gaste Martinez,Vanessa dos S Silva,Adriana P do Valle et al.
Marila Gaste Martinez et al.
Background/aims: There is disagreement regarding the performance of conventional optical microscopy to assess the origin of hematuria. The aim of this study was to determine the optimal cutoff point for dysmorphic cells i...
Randomized Controlled Trial
Nephron. Clinical practice. 2014;128(1-2):88-94. DOI:10.1159/000367848 2014