Kathinka Schmidt Slørdahl,Eva Skovlund,Jan-Åge Olsen et al.
Kathinka Schmidt Slørdahl et al.
Background and purpose: Chemoradiotherapy (CRT) for squamous cell carcinoma of the anus (SCCA) results in favorable survival. However, treatment intensity must be balanced against late side effects. The aim of this curren...
Incidence, characteristics, and survival in early- and late-onset colorectal cancer [0.03%]
早发和晚发结直肠癌的发病率、临床特点及生存情况
Tanja Hukkinen,Karri Seppä,Nea Malila et al.
Tanja Hukkinen et al.
Background and purpose: To study incidence changes, tumor characteristics, and relative survival (RS) among patients with early- (18-49 years) and late-onset (≥50 years) colorectal cancer (CRC). Patient/material and meth...
Internal mammary node irradiation in early breast cancer - target coverage and implications on dose to organs at risk [0.03%]
乳腺癌内乳淋巴结照射(I&M)的靶区覆盖及危及器官受量分析
Lovisa Berg,Jeanette Sporre,Elisabeth Kjellén et al.
Lovisa Berg et al.
Purpose: Indications for radiotherapy (RT) of the internal mammary nodes (IMN) in early breast cancer vary between countries. While studies indicate benefits, IMN RT increases the dose to the heart and lungs, and the risk...
Optimal treatment duration in metastatic renal cell carcinoma patients responding to immune checkpoint inhibitors: should we treat beyond two years? [0.03%]
免疫检查点抑制剂治疗转移性肾细胞癌患者的最佳疗程:是否需要治疗超过两年?
Alexander Decruyenaere,Gennigens Christine,Rottey Sylvie et al.
Alexander Decruyenaere et al.
Background and purpose: Optimal treatment duration is unknown in metastatic renal cell carcinoma (mRCC) responding to immune checkpoint inhibitors (ICPIs). Prolonged treatment can lead to late toxicity, burden for day cli...
Preclinical study of reirradiation with hyperthermia in recurrent murine tumors and normal mouse skin [0.03%]
重复放疗联合热疗对小鼠肿瘤和正常皮肤的预临床研究
Charlemagne A Folefac,Priyanshu M Sinha,Niels Bassler et al.
Charlemagne A Folefac et al.
Background: Re-irradiation is an essential treatment option for recurrent tumours but is limited by normal tissue tolerance. Hyperthermia can enhance radiation efficacy by impairing DNA repair and improving tumor oxygenat...
Role of prophylactic cranial irradiation in patients with limited disease small cell lung cancer: A Danish single institution cohort [0.03%]
预防性全脑照射在局限期小细胞肺癌患者中的作用:丹麦单中心队列研究
Sara Linde,Marianne Maquard Knap,Lone Hoffmann et al.
Sara Linde et al.
Background and purpose: Prophylactic cranial irradiation (PCI) is part of standard treatment for patients with limited disease small cell lung cancer (LD-SCLC), treated with curative intent. However, doubt has been raised...
Real-world insights into moderately hypofractionated thoracic radiotherapy in elderly and multimorbid patients with stage II/III NSCLC: a retrospective study [0.03%]
关于老年和合并症多发的II/III期非小细胞肺癌患者的中度低分割胸部放疗的真实世界研究:一项回顾性研究
Helene Kravutske,Sina Mansoorian,Lukas Käsmann et al.
Helene Kravutske et al.
Purpose: Investigating real-world outcomes of moderately hypofractionated radiotherapy (hypoRT) in elderly and multimorbid stage IIB-IIIC non-small-cell lung cancer (NSCLC) patients ineligible for concurrent chemoradiatio...
Clinical workflow for reirradiation: national consensus recommendations on imaging, treatment planning, dose accumulation, and treatment delivery [0.03%]
再程放疗临床流程:影像、计划、剂量积累和治疗实施的国家共识推荐意见
Laura P Kaplan,Rebecca J Tobin,Ane Appelt et al.
Laura P Kaplan et al.
Background and purpose: Reirradiation is becoming more frequent in clinical practice. However, workflows and practices vary widely between clinics, as general guidelines are scarce or lacking in practical detail. This pap...
Comparative proton and photon treatment plans in children treated for neuroblastoma [0.03%]
儿童神经母细胞瘤患者的质子治疗与光子治疗计划的比较分析
Anna Embring,Ingrid Kristensen,Martin P Nilsson et al.
Anna Embring et al.
Background and purpose: Neuroblastoma is the most common extracranial solid tumour in children. Radiotherapy is commonly part of the multimodal treatment for high-risk patients. The aim of this study is to analyse doses t...
Regional atrophy, cellular plasticity, and regenerative potential in irradiated murine salivary glands [0.03%]
放射引起的鼠模型颌下腺的区域萎缩、细胞可塑性和再生潜能
Inga Solgård Juvkam,Olga Zlygosteva,Olaf Joseph Franciscus Schreurs et al.
Inga Solgård Juvkam et al.
Background and purpose: Radiotherapy of head and neck cancer may cause detrimental late side effects such as fibrosis and hyposalivation. We investigated mouse salivary glands after fractionated irradiation, with the aim ...