Ultra-hypofractionated radiotherapy with focal boost for high-risk localized prostate cancer (HYPO-RT-PC-boost): in silico evaluation with histological reference [0.03%]
超高分次放射治疗加局部强化治疗高危局限性前列腺癌(HYPO-RT-PC-boost)：基于组织学的仿真评估
Erik Nilsson,Anneli Nilsson,Joakim Jonsson et al.
Erik Nilsson et al.
Background and purpose: The study aims to evaluate dosimetric properties of hypofractionated treatment plans integrating focal boost, using registered whole-mount histopathology (WMHP) as reference standard. ...
Cost of treatment of metastatic non-small lung cancer in Sweden, 2011-2023 [0.03%]
瑞典2011年至2023年转移性非小细胞肺癌治疗费用
Kun Kim,Michael Sweeting,Nils Wilking et al.
Kun Kim et al.
Background and purpose: Metastatic non-small cell lung cancer (mNSCLC) contributes to the economic burden. Over the past decade, treatment has evolved with the introduction of epidermal growth factor receptor (EGFR) anapl...
Integrating 2D dosimetry and cell survival analysis for predicting local effect in spatially fractionated radiotherapy [0.03%]
基于二维剂量学和细胞存活分析的空间分割放射治疗局部效应预测研究
Delmon Arous,Jacob Larsen Lie,Nina Frederike Jeppesen Edin et al.
Delmon Arous et al.
Background and purpose: Robust methods for analysis and prediction of local cell survival after spatially fractionated radiotherapy (SFRT) in vitro remain limited. We present a methodology integrating spatial dosimetry wi...
How do health literacy and chronic disease influence the diagnostic evaluation of patients with lung cancer symptoms? [0.03%]
健康素养和慢性病如何影响具有肺癌症状患者的诊断评估？
Lisa Maria Sele Sætre,Kirubakaran Balasubramaniam,Sonja Wehberg et al.
Lisa Maria Sele Sætre et al.
Background and purpose: Smoking status, health literacy challenges and chronic diseases may influence the diagnostic evaluation of patients presenting with lung cancer symptoms (LCSs) in general practice. This study aimed...
Development and evaluation of a lymph node invasion risk prediction model in intermediate- and high-risk prostate cancer patients [0.03%]
中高危前列腺癌患者淋巴结转移风险预测模型的建立与评价
Håkon Ramberg,Manuela Zucknick,Francesco Barletta et al.
Håkon Ramberg et al.
Background and purpose: Many prostate cancer patients undergoing pelvic lymph node dissection (PLND) have no sign of lymph node invasion (LNI) during final pathological assessment. To improve preoperative staging accuracy...
Determining the effects of hyperthermia on the tumor and acute normal tissue response of FLASH radiation [0.03%]
确定高温对FLASH辐照的肿瘤和急性正常组织反应的影响
Priyanshu Manojkumar Sinha,Line Kristensen,Charlemagne Asonganyi Folefac et al.
Priyanshu Manojkumar Sinha et al.
Introduction: There is limited indication of how hyperthermia would influence the unique proposition of FLASH radiation - its ability to maintain comparable tumor response while offering protection to normal tissues. Henc...
Low b-values in apparent diffusion coefficient calculations overestimate diffusion in rectal cancer [0.03%]
低b值对表观扩散系数计算中直肠癌的弥散度估计过高
Johanna A Hundvin,Marius Bornstein,Anne Negård et al.
Johanna A Hundvin et al.
Background and purpose: The apparent diffusion coefficient (ADC), derived from diffusion-weighted MRI (DWI), is commonly calculated using a monoexponential model. However, there is no consensus on optimal b-value selectio...
Observational Study
Acta oncologica (Stockholm, Sweden). 2025 Oct 19:64:1430-1436. DOI:10.2340/1651-226X.2025.44028 2025
Natural killer cell activity in prostate cancer patients treated with curative radiotherapy with or without androgen deprivation therapy: an observational study [0.03%]
根治性放疗伴或不伴雄激素剥夺治疗的前列腺癌患者自然杀伤细胞活性的观察研究
Stine V Eriksen,Christine V Madsen,Signe Timm et al.
Stine V Eriksen et al.
Background and purpose: Natural killer (NK) cells play an important role in defense against cancer. Low NK cell activity (NKA) has been linked to prostate cancer (PCa) detection, and effective NKA may be associated with b...
Observational Study
Acta oncologica (Stockholm, Sweden). 2025 Oct 19:64:1420-1429. DOI:10.2340/1651-226X.2025.44007 2025
Real-world outcomes after concurrent chemo-radiotherapy in patients with locally advanced esophageal and gastroesophageal junction cancer [0.03%]
同步放化疗在局部晚期食管和胃食管连接部癌患者中的预后评估
Hanna Rahbek Mortensen,Lone Hoffmann,Marianne Nordsmark et al.
Hanna Rahbek Mortensen et al.
Background and purpose: Standard treatment for esophageal (EC) and gastroesophageal junction (GEJ) cancer includes neoadjuvant chemo-radiotherapy (nCRT), followed by surgery or definitive chemo-radiotherapy (dCRT) for ino...
Nina Fanni,Eva Haglind,Sofia Heyman et al.
Nina Fanni et al.
Background and purpose: Anal cancer is treated with chemoradiotherapy and with salvage surgery in case of local failure. Curation rate depends on tumour stage but is overall high (80-90%). This study explored anal cancer ...