Impact of pathological tumor response after CROSS neoadjuvant chemoradiotherapy followed by surgery on long-term outcome of esophageal cancer: a population-based study [0.03%]
新辅助放化疗后手术食管癌患者的长期结局与病理肿瘤消退的相关性:基于人口的队列研究
Ali Al-Kaabi,Rachel S van der Post,Leonie R van der Werf et al.
Ali Al-Kaabi et al.
Background: With increasing interest in organ-preserving strategies for potentially curable esophageal cancer, real-world data is needed to understand the impact of pathological tumor response after neoadjuvant chemoradio...
Identification of a novel resistance mechanism in venetoclax treatment and its prediction in chronic lymphocytic leukemia [0.03%]
识别维奈克拉治疗中的新型耐药机制及其在慢性淋巴细胞白血病中的预测价值
Ferenc Takács,Gábor Mikala,Noémi Nagy et al.
Ferenc Takács et al.
Background: The Bcl-2 inhibitor venetoclax has been recently introduced into the treatment of chronic lymphocytic leukemia. Venetoclax is a highly effective drug, however acquired resistance may make long-term treatment c...
Self-reported questionnaires for lymphoedema: a systematic review of measurement properties using COSMIN framework [0.03%]
淋巴水肿自填式问卷的系统评价:采用COSMIN框架评估测量性能属性
Vincent Singh Paramanandam,Mi-Joung Lee,Sharon L Kilbreath et al.
Vincent Singh Paramanandam et al.
Introduction: Lymphoedema may develop as a result of numerous genetic and traumatic causes; however, treatment for cancer is the most common cause of its development in more economically developed nations. This systematic...
Efficacy evaluation of anticancer agents in single-arm clinical trials: analysis of review reports from Pharmaceuticals and Medical Devices Agency [0.03%]
单臂临床试验抗肿瘤药物疗效评价:日本医药医疗器械机构审评报告分析
Ken Hatogai,Yuka Kato,Chikara Hirase
Ken Hatogai
Background: Comparative studies often cannot be conducted for cancer types with a small patient population. We reviewed the efficacy evaluations of new drug approvals in Japan based on the results of single-arm clinical t...
Extending hypofractionated stereotactic body radiotherapy to tumours larger than 70cc - effects and side effects [0.03%]
对大于70cc的肿瘤进行超低分割立体定向体放射治疗的效果和副作用
Vitali Grozman,Eva Onjukka,Peter Wersäll et al.
Vitali Grozman et al.
Background and purpose: Stereotactic body radiotherapy (SBRT) for tumours ≥5 cm is poorly studied and its utility and feasibility is uncertain. We here report the Karolinska experience of SBRT in this setting. ...
Immune cell score, PD-L1 expression and prognosis in esophageal cancer [0.03%]
免疫细胞评分、PD-L1表达及食管癌预后之间的关系
Anna Junttila,Juha P Väyrynen,Maarit Ahtiainen et al.
Anna Junttila et al.
Rationale and design of REGINA, a phase II trial of neoadjuvant regorafenib, nivolumab, and short-course radiotherapy in stage II and III rectal cancer [0.03%]
REGINA研究的设计与方案:关于regorafenib、nivolumab和短疗程放疗在II/III期直肠癌新辅助治疗中应用的II期临床试验
Giacomo Bregni,Caroline Vandeputte,Andrea Pretta et al.
Giacomo Bregni et al.
Investigating the potential of deep learning for patient-specific quality assurance of salivary gland contours using EORTC-1219-DAHANCA-29 clinical trial data [0.03%]
基于EORTC-1219-DAHANCA-29临床试验数据的深度学习在个性化勾画唾液腺器官轮廓QA中的应用研究
Hanne Nijhuis,Ward van Rooij,Vincent Gregoire et al.
Hanne Nijhuis et al.
Introduction: Manual quality assurance (QA) of radiotherapy contours for clinical trials is time and labor intensive and subject to inter-observer variability. Therefore, we investigated whether deep-learning (DL) can pro...
Differential effects of colorectal cancer screening across sociodemographic groups in Denmark: a register-based study [0.03%]
丹麦结直肠癌筛查项目在不同社会人口群体中的效果差异:基于注册信息的队列研究
Anna Vera Jørring Pallesen,Jørn Herrstedt,Rudi G J Westendorp et al.
Anna Vera Jørring Pallesen et al.
Introduction: Colorectal cancer (CRC) does not affect different sociodemographic groups uniformly. CRC screening programmes could seek to reduce this inequality; however, the screening programmes themselves might be subje...
Effects of football fitness training on lymphedema and upper-extremity function in women after treatment for breast cancer: a randomized trial [0.03%]
足球体能训练对乳腺癌治疗后女性淋巴水肿和上肢功能的影响:一项随机试验
Kira Bloomquist,Peter Krustrup,Bjørn Fristrup et al.
Kira Bloomquist et al.
Background: Breast cancer survivors are encouraged to be physically active. A recent review suggests that football training is an effective exercise modality for women across the lifespan, positively influencing health va...
Randomized Controlled Trial
Acta oncologica (Stockholm, Sweden). 2021 Mar;60(3):392-400. DOI:10.1080/0284186X.2020.1868570 2021