Immunomodulatory effects of ultrasonically lysed Bifidobacterium breve on Pam3CSK4-stimulated J774A.1 macrophages via SIRT1/NRF2 activation and NF-κB suppression [0.03%]
声音处理的短双歧杆菌通过SIRT1/NRF2活化和抑制NF-κB对Pam3CSK4刺激的小胶质细胞J774A.1免疫调节作用研究
Sheng Wang,Meixia Zheng,Juan Chen et al.
Sheng Wang et al.
Background: Bacterial lysates, which contain cell wall components and intracellular metabolites, have emerged as important modulators of macrophage immune function through interactions with pattern recognition receptors (...
Genomic and phenotypic heterogeneity of Klebsiella aerogenes in a single host: plasmid loss and tissue-specific virulence gene expression during host adaptation [0.03%]
条件致病菌克雷伯氏菌在单个宿主体内的基因型和表型异质性：适应宿主过程中的质粒丢失及组织特异性毒力基因表达
Luis Duarte-Zambrano,Neli Nava-Domínguez,Juan Pablo Ramírez-Hinojosa et al.
Luis Duarte-Zambrano et al.
Klebsiella aerogenes is an opportunistic pathogen increasingly associated with healthcare-associated infections and severe respiratory complications. However, it's in vivo adaptation during host colonization remains poorly understood. We ch...
Hidden in the community: poly-clonal spread of KPC- or NDM-producing Klebsiella pneumoniae revealed by whole-genome sequencing in Southeastern Brazil [0.03%]
全基因组测序揭示的Southeastern巴西社区隐匿的产KPC或NDM肺炎克雷伯菌多株系传播事件
Carlos H Camargo,Taise C D M Barbosa,Amanda Y Yamada et al.
Carlos H Camargo et al.
Objectives: Carbapenemase-producing Klebsiella pneumoniae remains a major driver of multidrug resistance, traditionally linked to healthcare-associated infections but its detection in community-acquired infections represe...
A novel Aureobasidium pullulans isolate for the biological control of Penicillium commune in potato decay and its optimization for enhanced antifungal activity using the Taguchi method [0.03%]
一种新型的出芽短梗霉菌株用于生物防治马铃薯腐烂病中的青霉菌及其利用Taguchi法优化增强抗真菌活性的方法
Noushin Shafiee,Keivan Beheshti-Maal,Hamid Reza Akkafi et al.
Noushin Shafiee et al.
Penicillium commune is a significant postharvest fungal pathogen responsible for blue mold rot in stored potatoes, resulting in substantial economic losses worldwide. In this study, we isolated and characterized a novel epiphytic strain of ...
Metabolomics study of the inhibitory effects of tubuloside A on Streptococcus suis biofilm [0.03%]
管皂苷A抑制猪链球菌生物被膜的代谢组学研究
Ruixiang Che,Yiyang Sun,Jianjun Zhao
Ruixiang Che
Streptococcus suis (S. suis) is an important zoonotic pathogen. Biofilm formation contributes to persistent and chronic infections, increases the difficulty of bacterial eradication, and may pose a threat to public health. Clinically, S. su...
Contact-independent antagonistic activity of endophytic Diaporthe biconispora PBS24-3 against Penicillium spp.: dual culture, culture filtrate, metabolomics, and molecular network analysis [0.03%]
内生菌Diaporthe biconispora PBS24-3与Penicillium spp.互抗活性：平皿对接、滤液、代谢组及分子网络分析
Ling Yang,Yee Shin Tan,Chia Wei Phan et al.
Ling Yang et al.
The treatment of invasive fungal infections remains challenging due to the limited availability of antifungal agents and the rapid emergence of drug resistance. Endophytic fungi, shaped by chemically mediated interactions within plant-assoc...
Eco-phylogenetic diversity and relative pigment production in environmental Talaromyces purpurogenus isolates [0.03%]
环境中的塔拉拟青霉菌属分离株的生态谱系多样性及其相对色素产生能力
Youssuf Gherbawy,Amera Alqahtani,Hanan Alomari et al.
Youssuf Gherbawy et al.
Talaromyces purpurogenus is a filamentous fungus capable of producing red polyketide-like pigments with potential as natural alternatives to synthetic colorants. This study investigated the ecological distribution, phylogenetic diversity, a...
Docosahexaenoic acid alleviates DSS-induced colitis by regulating the gut microbiota and restoring the gut barrier [0.03%]
二十二碳六烯酸通过调节肠道微生物群和恢复肠屏障来缓解葡聚糖硫酸钠诱导的结肠炎
Sumin Wang,Shiping Hu,Yan Yan et al.
Sumin Wang et al.
Docosahexaenoic acid (DHA), a long-chain omega-3 polyunsaturated fatty acid, has well-recognized anti-inflammatory activity; however, the mechanisms underlying its protective effects in inflammatory bowel disease (IBD) remain incompletely u...
Identification of Acantamoeba isolated from water resources located in the northwest of Iran by using the high-resolution melting analysis assay [0.03%]
采用高分辨率溶解曲线分析法鉴别来自伊朗西北部水源的阿卡纳马拉样菌
Elham Hajialilo,Soodabeh Shabani,Babak Rahmani et al.
Elham Hajialilo et al.
Background: Free-living amoebae (FLA), such as Acanthamoeba, are protozoan parasites that take advantage of opportunities with a widespread distribution in various environmental sources, such as a wide range of water sour...
Preventive action of ketamine alone and in combination with antifungals on Candida biofilm formation in catheters [0.03%]
卡因和抗真菌药单独使用及联合使用对导管中白色念珠菌生物被膜形成的预防作用
Cecília Rocha da Silva,Lívia Gurgel do Amaral Valente Sá,Lisandra Juvêncio da Silva et al.
Cecília Rocha da Silva et al.
Purpose: This study investigates the repurposing potential of the anesthetic ketamine (KET) as a preventive agent, both alone and in combination with the azoles fluconazole (FLC) and itraconazole (ITR), against Candida sp...