Truffle fruiting occurs in chemically and microbially distinct soil niches [0.03%]
松露在化学和微生物特性不同的土壤生态位中生长结果实
Paul W Thomas,Muhammad Salman Zahid,Adrian Slater
Paul W Thomas
Ectomycorrhizal fungi (EMF) play critical roles in nutrient exchange, soil processes, and plant community structure, yet the mechanisms linking their environmental interactions to reproduction remain poorly understood. The black truffle (Tu...
Body temperature drives azole tolerance in Candida albicans by hindering the autophagic degradation of Erg11 [0.03%]
体温通过阻碍Erg11的自噬降解驱动白念珠菌对唑类药物的耐受性
Yanru Feng,Cheng Zhen,Wanqian Li et al.
Yanru Feng et al.
Human body temperature has been shown to limit the antifungal efficacy of azoles; however, the precise mechanisms underlying this limitation remain insufficiently understood. In this study, we observed that short-term exposure (24 h) to hum...
Ivan Ciliberti,Lucia De Luca,Raffaele Romano et al.
Ivan Ciliberti et al.
Aquaria that host ornamental fish may support a vast array of microorganisms, but to date, little information is available on these microbial ecosystems. In the present study, a polyphasic approach based on conventional and culture-independ...
Niaoduqing particles ameliorated tubulointerstitial fibrosis by suppressing IκB/NF-κB signalling pathway via inhibiting host- and gut microbiota-mediated tryptophan co-metabolism [0.03%]
肾毒清颗粒通过抑制宿主和肠道菌群介导的色氨酸共代谢抑制IκB/NF-κB信号通路改善 tubulointerstitial fibrosis
Li-Min Liu,Hong-Bin Fang,Yun-Fei Wang et al.
Li-Min Liu et al.
Tubulointerstitial fibrosis (TIF) is an inevitable outcome of progressive chronic kidney disease (CKD). Niaoduqing particles (NDQ) were developed for the treatment of CKD. However, the molecular mechanisms underlying the effect of NDQ on TI...
Microbiome-mediated plant immunity: Molecular signalling, community assembly, and emerging intergenerational feedback [0.03%]
肠道菌群介导的植物免疫机制：分子信号、群体组装及代际反馈效应
Xin Liu,Zhijie Ao,Xingcan Liu et al.
Xin Liu et al.
Classical pattern-triggered (PTI) and effector-triggered (ETI) immunity, developed in single-pathogen systems, illuminates how plants recognise molecular threats but cannot fully explain immune homeostasis within the dynamic microbial commu...
Vibrio anguillarum hijacks fish host CypA to activate Ras-MAPK signaling and promote Edwardsiella piscicida entry during co-infection [0.03%]
迟缓爱德华菌与鳗气单胞菌共感染时，鳗气单胞菌招募鱼的CypA以激活Ras-MAPK信号通路并促进迟缓爱德华菌入侵
Yifan Wang,Junze Wu,Yizhuo Wang et al.
Yifan Wang et al.
Edwardsiella piscicida is a major pathogen in marine aquaculture, and co-infection with Vibrio anguillarum dramatically exacerbates disease severity and mortality. However, the molecular mechanisms by which pathogens cooperatively exploit h...
TvNTPDase4, a surface ectonucleotidase of Trichomonas vaginalis, is a potential immunological marker for the diagnosis of trichomoniasis in women [0.03%]
TvNTPDase4是毛滴虫病女性患者免疫诊断的潜在生物标志物：功能和表达分析
Magno Sinval Pereira Ribeiro,Fernanda Gomes Cardoso,Saulo Almeida Menezes et al.
Magno Sinval Pereira Ribeiro et al.
Trichomoniasis is the most common non-viral sexually transmitted infection worldwide but remains underdiagnosed due to limitations of current diagnostic methods. Nucleoside triphosphate diphosphohydrolase (NTPDase) is an enzyme involved in ...
The SET domain group protein FonSDG1 regulates virulence through modulating the expression of ammonium permeases in Fusarium oxysporum f. sp. niveum [0.03%]
尖孢镰刀菌雪腐病无性型中SET结构域蛋白FonSDG1通过调节铵转运蛋白的表达调控其致病性
Jiajing Wang,Mengmeng Guo,Xiaohui Xiong et al.
Jiajing Wang et al.
Histone lysine methylation, catalyzed by a family of SET domain-containing histone lysine methyltransferases, modulates chromatin structure and accessibility, thereby regulating gene expression. In this study, we identified and characterize...
Dynamic dual roles of gut microbial metabolites in Alzheimer's disease: Translational insights for gut-brain axis interventions [0.03%]
肠道微生物代谢产物在阿尔茨海默病中的动态双重作用：肠-脑轴干预的转化见解
Xutao Ye,Xiaodong Jing,Zhongyuan Li et al.
Xutao Ye et al.
Alzheimer's disease (AD) is a complex neurodegenerative disorder in which the microbiome-gut-brain axis (MGBA) plays a crucial regulatory role through microbial metabolites. This review analyzes the concentration trajectories of representat...
Machine learning in applied microbiology, from data quality to model validation and implementation [0.03%]
机器学习在应用微生物学中的研究从数据质量到模型验证和实施
Rares A Barcan,Simone Carradori,Francisca Samsing et al.
Rares A Barcan et al.
Machine learning (ML) is now widely applied in microbiology, but its reliability varies markedly across domains. In this review, we analysed data from 254 scientific articles that evaluates ML through three linked dimensions including data ...