YAP promotes wound healing in diabetic mice by improving endothelial cell function via the regulation of SEMA3B [0.03%]
YAP通过调节SEMA3B促进糖尿病小鼠伤口愈合及内皮细胞功能改善作用机制研究
Linqi Su,Guoqi Cao,Chunyan Liu et al.
Linqi Su et al.
Impaired angiogenesis is a critical factor contributing to delayed wound healing in diabetes patients. This study aimed to investigate the role and underlying mechanism of semaphorin 3B (SEMA3B) and its upstream regulator Yes-associated pro...
Predicting DNA replication-related protein expression at the nucleus level from HE: A deep learning study with same-specimen paired data [0.03%]
基于同一样本配对数据的深度学习研究HE中与DNA复制相关的核蛋白表达预测
Takumi Urata,Saori Takeyama,Fumikazu Kimura et al.
Takumi Urata et al.
Background: The inference of molecular information from hematoxylin-eosin (HE) specimens may reduce the ancillary testing burden in digital pathology. Obj...
Whole-brain atlas of the wall lizard, Hemidactylus flaviviridis: A histo-anatomical perspective [0.03%]
黄绿壁虎的全脑图谱：组织学和解剖学角度
Vishesh Chauhan,Umesh Rai,Mamta Tripathy et al.
Vishesh Chauhan et al.
The current study provides the first histological whole-brain atlas of the lizard, Hemidactylus flaviviridis. Macroscopic analysis of the lizard brain demonstrates its gross morphology, including various fissures and major divisions, forebr...
From prion safety to morphology-preserving validation: Extending the implications of formic acid-treated brain tissue [0.03%]
从形貌安全到保持形貌的验证：甲酸处理脑组织的意义扩展
Rajesh Prasad Jayaswal,Kundan Kumar Chaubey,Shanoo Sharma et al.
Rajesh Prasad Jayaswal et al.
Beyond CoCl₂: Toward decision-grade hypoxia modeling in gastric cancer histobiology [0.03%]
超越CoCl₂：胃癌组织生物学中决策级低氧建模之路
Mulavagili Srikanth,Arshdeep Singh,M Vijayasimha
Mulavagili Srikanth
Hypoxia is a characteristic, although heterogeneous, of solid tumors, and experimental hypoxia is still far too frequently addressed as a single replaceable phenomenon. Yashiro et al. demonstrate in their recent article in Acta Histochemica...
Three-dimensional gelatin sponge culture potentiates MSC secretome to enhance full-thickness wound healing and induce hair follicle neogenesis via Wnt/β-catenin and TLR3/STAT3 activation in rats [0.03%]
三维明胶海绵培养促进间充质干细胞分泌组分增强全层伤口愈合及通过Wnt/β-catenin和TLR3/STAT3激活诱导新生毛囊生成：大鼠模型研究
Xiang Liu,Jiaqi Cheng,Junhong Zhao et al.
Xiang Liu et al.
This study aimed to produce a high-quality mesenchymal stem cell-derived secretome (MSC-sec) using a three-dimensional culture system to enhance its therapeutic potential for skin wounds. Human umbilical cord-derived MSCs were cultured on o...
Quercetin-loaded microcapsules modulate intestinal serotonin, cell proliferation, and mucosa architecture in adjuvant-induced arthritis [0.03%]
檞皮素微囊调节佐剂性关节炎小鼠肠腔血清素、细胞增殖及黏膜结构分布
Lídia Rodrigues Cicero,Gleison Daion Piovezana Bossolani,João Victor Kuller et al.
Lídia Rodrigues Cicero et al.
We investigated whether the effect of treatment with quercetin-loaded microcapsules 10 mg/kg promotes anti-inflammatory action and prevents damage to the intestinal wall in the jejunum of rats with adjuvant-induced arthritis. Thirty Holtzma...
Mesenchymal stem cell mitochondrial transfer effectively protects Leber's Hereditary Optic Neuropathy (LHON) mutant cells from mitochondrial damage [0.03%]
间充质干细胞线粒体移植有效保护莱伯遗传性视神经病变细胞免遭线粒体损伤
Aswathy P Nair,Aishwarya Janaki P,Janani Gopalarethinam et al.
Aswathy P Nair et al.
Leber's Hereditary Optic Neuropathy (LHON) is the most prevalent mitochondrial inherited disorder, primarily caused by primary mitochondrial mutations. Clinically, LHON is characterized by degeneration of optic nerves that leads to acute or...
Sodium valproate induces chromatin remodeling in U-251MG glioblastoma cells [0.03%]
丙戊酸钠可引起U-251MG胶质母细胞瘤细胞的染色质重塑
Camila B M Oliveira,Marina A Rocha,Maria Luiza S Mello
Camila B M Oliveira
The development and progression of glioblastoma, the most aggressive malignant intracranial tumor with a poor prognosis, are influenced by mutations, oncogene overexpression, and epigenetic factors, particularly those relating to DNA methyl...
Nuclear image changes in cells originating from tenocytes that migrated from tendon explants [0.03%]
滑膜细胞衍生于肌腱组织中迁移出的纤维鞘细胞及其核形态变化研究
Eli Heber Martins Dos Anjos,Maria Luiza Silveira Mello,Benedicto de Campos Vidal
Eli Heber Martins Dos Anjos
Tenocytes migrating from cultured rat tendon explants have been shown to aggregate and gradually align in parallel rows with the tendon's long axis as the explant culture period extends to 12 days, leading to structure remodeling of collage...