Pediatric Pancreatoblastoma with an NRAS Mutation: Expanding the Spectrum of Genetic Alterations in Pancreatoblastoma [0.03%]
NRAS基因突变在儿童胰腺blastoma中的作用：扩大遗传改变在胰腺blastoma中的范围
Catherine K Gestrich,John M Skaugen,Andrew Bukowinski et al.
Catherine K Gestrich et al.
Pancreatoblastoma is a rare malignancy that primarily affects children and involves abnormalities in the WNT/β-catenin signaling pathway. It demonstrates diverse differentiation mimicking fetal pancreatic development resulting in different...
Bile Duct Targeting or Preservation: Contrasting Liver Histology in Langerhans Cell Histiocytosis and Disseminated Juvenile Xanthogranuloma [0.03%]
胆管靶向或保护：朗格汉斯细胞组织细胞增生症和广泛性青少年黄色瘤的肝脏组织学对比
Margaux Däniker,Frédéric Baleydier,Nathalie M Rock et al.
Margaux Däniker et al.
Liver involvement by histiocytic and dendritic cell neoplasms signals high-risk disease, often necessitating closer monitoring and aggressive management. Severe cases may progress to liver failure, requiring transplantation. Liver involveme...
Novel Finding of PLAG1 Overexpression and COL3A1::PLAG1 Rearrangement in Nevus Lipomatosus Superficialis [0.03%]
nevus lipomatosus superficialis中PLAG1过表达和COL3A1::PLAG1异常融合的新发现
Weiming Yu,Xiao Zhu,Erik Nohr
Weiming Yu
Nevus lipomatosus superficialis (NLS) is an uncommon benign skin lesion and characterized by aggregates of mature adipose tissue ectopically among the collagen bundles of the dermis. The precise etiology of NLS remains poorly understood, an...
Gross and Histopathological Findings of 111 Triplet Placentas: A Descriptive Analysis [0.03%]
111例三胎胎盘的肉眼和组织病理学表现描述性分析
Eva Manuela Pena-Burgos,María De La Calle,Jose Juan Pozo-Kreilinger et al.
Eva Manuela Pena-Burgos et al.
Introduction: Triplet pregnancies have risen in recent decades due to assisted reproductive technology (ART) and are considered high-risk. Placental evaluation is crucial to understanding their outcomes, yet pathological ...
Prenatal Isolated Congenital Diaphragmatic Hernia: A Rare Clinical Presentation of a GATA4 Pathogenic Variant [0.03%]
GATA4致病性变异罕见临床表现之一：产前孤立性先天性膈疝
Nea Tulonen,Jussi Tallus,Heidi Kaprio et al.
Nea Tulonen et al.
Congenital diaphragmatic hernia is a genetically heterogeneous condition with a developmental defect in the diaphragm. The GATA4 gene is essential for fetal heart development, and pathogenic GATA4 variants are a known cause of structural co...
Sinusoidal Hepatic Growth Pattern of Metastatic DICER1-Mutated Urethral Sarcoma Mimicking Hepatocellular Carcinoma [0.03%]
伴有DICER1基因突变的尿道肉瘤肝转移呈现类 hepatocellular carcinoma生长模式
Xiaoqin Liu,Soo-Jin Cho,Grace E Kim et al.
Xiaoqin Liu et al.
Although liver metastases from solid tumors are common and typically present as discrete masses, a sinusoidal pattern of hepatic involvement is rare, especially in sarcomas. We report a case of DICER1-mutated urethral sarcoma exhibiting thi...
Fatma Cavide Sönmez,Marcus Pauly,Annette M Müller
Fatma Cavide Sönmez
Multicystic adenomatoid pancreatic hamartoma (MAPH) is a rare lesion of the pancreas, particularly in the pediatric age group with only a few cases reported in the literature. We report an unusual cystic lesion diagnosed MAPH in a 26-month-...
Left Pulmonary Artery Sling: Anatomy, Associations, and Outcome of Surgical Repair as Demonstrated by Autopsies [0.03%]
左肺动脉吊带的解剖结构、关联及手术修复的结局（基于尸体解剖）
Yan Zhou,Stephen P Sanders,Chrystalle Katte Carreon
Yan Zhou
Left pulmonary artery (LPA) sling is a rare congenital anomaly in which the LPA abnormally originates from the right pulmonary artery (RPA) and courses between the trachea and esophagus to reach the left pulmonary hilum. This anomaly is fre...
PRRX1-Rearranged Mesenchymal Tumor: A Case Report and Review of the Literature [0.03%]
关于PRRX1重排间叶肿瘤的病例报告及文献复习
Geoffrey C Halling,Jonathan B McHugh,Amer Heider
Geoffrey C Halling
PRRX1-rearranged mesenchymal/fibroblastic tumor is a recently proposed, molecularly defined soft tissue tumor, which has not yet been included in the WHO's most recent edition of soft tissue tumors. This entity has previously been reported ...