Gestational Alloimmune Liver Disease and Congenital Athymia in a Neonate Born via In Vitro Fertilization Surrogacy [0.03%]
供胎 alloimmune 肝病和因体外受精代孕出生的新生儿先天性无胸腺症
Meifang Wu,Joel Hernandez,Ryan Rebbe et al.
Meifang Wu et al.
We report a rare case of gestational alloimmune liver disease (GALD) and congenital athymia in a 3-week-old premature male neonate, born via in vitro fertilization (IVF) surrogacy. The neonate initially presented with disseminated intravasc...
Sara Coacci,Stephen P Sanders,Chrystalle Katte Carreon
Sara Coacci
Ebstein anomaly (EA) is a rare congenital heart defect characterized by an abnormal development of the tricuspid valve (TV) and ventricular myocardium. The TV is displaced downward into the right ventricle (RV), leading to an atrialized bas...
Primordial Germ Cells in the Human Fetal Brain: Origins of Intracranial Germ Cell Tumours [0.03%]
人胎儿大脑原发生殖细胞在脑内生殖细胞瘤的发生中的起源
Stephanie R Beldick,Patrick Shannon
Stephanie R Beldick
Germ cell tumours are heterogeneous tumours arising in the gonads, though they also affect extragonadal sites, including midline structures of the central nervous system (CNS). While intracranial germ cell tumours (iGCTs) are extensively ch...
Pediatric Pancreatoblastoma with an NRAS Mutation: Expanding the Spectrum of Genetic Alterations in Pancreatoblastoma [0.03%]
NRAS基因突变在儿童胰腺blastoma中的作用：扩大遗传改变在胰腺blastoma中的范围
Catherine K Gestrich,John M Skaugen,Andrew Bukowinski et al.
Catherine K Gestrich et al.
Pancreatoblastoma is a rare malignancy that primarily affects children and involves abnormalities in the WNT/β-catenin signaling pathway. It demonstrates diverse differentiation mimicking fetal pancreatic development resulting in different...
Bile Duct Targeting or Preservation: Contrasting Liver Histology in Langerhans Cell Histiocytosis and Disseminated Juvenile Xanthogranuloma [0.03%]
胆管靶向或保护：朗格汉斯细胞组织细胞增生症和广泛性青少年黄色瘤的肝脏组织学对比
Margaux Däniker,Frédéric Baleydier,Nathalie M Rock et al.
Margaux Däniker et al.
Liver involvement by histiocytic and dendritic cell neoplasms signals high-risk disease, often necessitating closer monitoring and aggressive management. Severe cases may progress to liver failure, requiring transplantation. Liver involveme...
Novel Finding of PLAG1 Overexpression and COL3A1::PLAG1 Rearrangement in Nevus Lipomatosus Superficialis [0.03%]
nevus lipomatosus superficialis中PLAG1过表达和COL3A1::PLAG1异常融合的新发现
Weiming Yu,Xiao Zhu,Erik Nohr
Weiming Yu
Nevus lipomatosus superficialis (NLS) is an uncommon benign skin lesion and characterized by aggregates of mature adipose tissue ectopically among the collagen bundles of the dermis. The precise etiology of NLS remains poorly understood, an...
Gross and Histopathological Findings of 111 Triplet Placentas: A Descriptive Analysis [0.03%]
111例三胎胎盘的肉眼和组织病理学表现描述性分析
Eva Manuela Pena-Burgos,María De La Calle,Jose Juan Pozo-Kreilinger et al.
Eva Manuela Pena-Burgos et al.
Introduction: Triplet pregnancies have risen in recent decades due to assisted reproductive technology (ART) and are considered high-risk. Placental evaluation is crucial to understanding their outcomes, yet pathological ...
Prenatal Isolated Congenital Diaphragmatic Hernia: A Rare Clinical Presentation of a GATA4 Pathogenic Variant [0.03%]
GATA4致病性变异罕见临床表现之一：产前孤立性先天性膈疝
Nea Tulonen,Jussi Tallus,Heidi Kaprio et al.
Nea Tulonen et al.
Congenital diaphragmatic hernia is a genetically heterogeneous condition with a developmental defect in the diaphragm. The GATA4 gene is essential for fetal heart development, and pathogenic GATA4 variants are a known cause of structural co...
Sinusoidal Hepatic Growth Pattern of Metastatic DICER1-Mutated Urethral Sarcoma Mimicking Hepatocellular Carcinoma [0.03%]
伴有DICER1基因突变的尿道肉瘤肝转移呈现类 hepatocellular carcinoma生长模式
Xiaoqin Liu,Soo-Jin Cho,Grace E Kim et al.
Xiaoqin Liu et al.
Although liver metastases from solid tumors are common and typically present as discrete masses, a sinusoidal pattern of hepatic involvement is rare, especially in sarcomas. We report a case of DICER1-mutated urethral sarcoma exhibiting thi...
Fatma Cavide Sönmez,Marcus Pauly,Annette M Müller
Fatma Cavide Sönmez
Multicystic adenomatoid pancreatic hamartoma (MAPH) is a rare lesion of the pancreas, particularly in the pediatric age group with only a few cases reported in the literature. We report an unusual cystic lesion diagnosed MAPH in a 26-month-...