Niels Grarup,Ida Moltke,Anders Albrechtsen et al.
Niels Grarup et al.
Type 2 diabetes (T2D) is an increasing health problem worldwide with particularly high occurrence in specific subpopulations and ancestry groups. The high prevalence of T2D is caused both by changes in lifestyle and genetic predisposition. ...
Complex Genetics of Type 2 Diabetes and Effect Size: What have We Learned from Isolated Populations? [0.03%]
2型糖尿病的复杂遗传学和效应值：孤立人群教会了我们什么？
Anup K Nair,Leslie J Baier
Anup K Nair
Genetic studies in large outbred populations have documented a complex, highly polygenic basis for type 2 diabetes (T2D). Most of the variants currently known to be associated with T2D risk have been identified in large studies that include...
Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk [0.03%]
2型糖尿病的遗传学：从哪一方继承患病风险很重要
Valeriya Lyssenko,Leif Groop,Rashmi B Prasad
Valeriya Lyssenko
Type 2 diabetes (T2D) results from a co-occurrence of genes and environmental factors. There are more than 120 genetic loci suggested to be associated with T2D, or with glucose and insulin levels in European and multi-ethnic populations. Ri...
Pancreas Transplantation of US and Non-US Cases from 2005 to 2014 as Reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) [0.03%]
美国及非美国2005年至2014年胰腺移植病例（来自器官共享方案和移植登记系统的报告）
Angelika C Gruessner,Rainer W G Gruessner
Angelika C Gruessner
This report is an update of pancreas and kidney transplant activities in the US and non-US region in two periods, 2005-2009 and 2010-2014. The aim of the report was to analyze transplant progress and success in the US compared to non-US cou...
Metformin Treatment Does Not Affect Testicular Size in Offspring Born to Mothers with Gestational Diabetes [0.03%]
二甲双胍治疗不会影响妊娠糖尿病母亲出生后代的睾丸大小
Kristiina Tertti,Jorma Toppari,Helena E Virtanen et al.
Kristiina Tertti et al.
Objectives: Studies in rodents suggest that metformin treatment during pregnancy may have harmful effects on testicular development in offspring. Our aim was to determine whether metformin treatment of gestational diabete...
Genetic Determination of Serum Levels of Diabetes-Associated Adipokines [0.03%]
与糖尿病相关脂肪细胞因子的血清水平的基因决定因素
Dorit Schleinitz
Dorit Schleinitz
Adipose tissue secretes an abundance of proteins. Some of these proteins are known as adipokines and adipose-derived hormones which have been linked with metabolic disorders, including type 2 diabetes, and even with cancer. Variance in seru...
Novel Genetic Actors of Diabetes-Associated Microvascular Complications: Retinopathy, Kidney Disease and Neuropathy [0.03%]
与糖尿病相关的微血管并发症的新遗传因素：视网膜病变、肾脏疾病和神经病
Samaneh Davoudi,Lucia Sobrin
Samaneh Davoudi
Both type 1 and type 2 diabetes mellitus can lead to the common microvascular complications of diabetic retinopathy, kidney disease, and neuropathy. Diabetic patients do not universally develop these complications. Long duration of diabetes...
Beyond the Protein-Coding Sequence: Noncoding RNAs in the Pathogenesis of Type 2 Diabetes [0.03%]
超越蛋白质编码序列：非编码RNA在2型糖尿病发病机制中的作用
Johanna K DiStefano
Johanna K DiStefano
Diabetes mellitus results from a deficiency or failure to maintain normal glucose homeostasis. The most common form of the disease is type 2 diabetes (T2D), a progressive metabolic disorder characterized by elevated glucose levels that deve...
Simplified Diagnosis of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes Using Ewing's Battery [0.03%]
简化2型糖尿病患者心血管自主神经病变Ewing量表诊断流程
Kalliopi Pafili,Grigorios Trypsianis,Dimitrios Papazoglou et al.
Kalliopi Pafili et al.
Aim: To find a potential simplification of the established Ewing's battery for the diagnosis of cardiovascular autonomic neuropathy (CAN) in type 2 diabetes (T2D). ...
Kamyar Vaziri,Stephen G Schwartz,Nidhi Relhan et al.
Kamyar Vaziri et al.
Diabetic retinopathy is a common microvascular complication of diabetes mellitus. It affects a substantial proportion of US adults over age 40. The condition is a leading cause of visual loss. Much attention has been given to expanding the ...