Jianxun Wang,Ye Song,Qianwen Wang et al.
Jianxun Wang et al.
Type 1 and type 2 diabetic patients are at increased risk of cardiomyopathy and heart failure is a major cause of death for these patients. Cardiomyopathy in diabetes is associated with a cluster of features including decreased diastolic co...
Replenishing Peripheral CD4(+) Regulatory T Cells: A Possible Immune-Intervention Strategy in Type 1 Diabetes? [0.03%]
补充外周CD4+(+)调节性T细胞：在I型糖尿病中可能的一种免疫干预策略？
Charles Sia
Charles Sia
Controlling the diabetogenic activity of peripheral islet antigen-specific T cells is essential to halt the progression of autoimmunity that leads to the development of type 1 diabetes mellitus (T1DM). Over the past years, evidence has been...
Death pathways in T cell homeostasis and their role in autoimmune diabetes [0.03%]
T细胞稳态中的死亡途径及其在自身免疫糖尿病中的作用
Matthew A Gronski,Michael Weinem
Matthew A Gronski
T cell apoptosis is a process necessary for central and peripheral tolerance. It ensures the proper removal of autoreactive T cells during thymic development as well as T cell homeostasis and the downregulation of immune responses against a...
Prevalence of Type 2 diabetic patients within the targets of care guidelines in daily clinical practice: a multi-center study in Brazil [0.03%]
巴西多中心研究：日常临床实践中的2型糖尿病患者是否符合护理指南的标准
Marilia de Brito Gomes,Daniel Gianella,Manuel Faria et al.
Marilia de Brito Gomes et al.
Major clinical studies have shown that the targets for blood glucose, lipid profile and blood pressure in type 2 diabetic patients are difficult to maintain in clinical practice. However, there are few data concerning South American populat...
The impact of the angiotensin-converting enzyme insertion/deletion polymorphism on severe hypoglycemia in Type 2 diabetes [0.03%]
血管紧张素转换酶插入/缺失基因多态性对2型糖尿病患者严重低血糖的影响
Rachel M Freathy,Kathryn F Lonnen,Anna M Steele et al.
Rachel M Freathy et al.
The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme gene (ACE) is associated with altered serum ACE activity. Raised ACE levels and the ACE DD genotype are associated with a 3.2 to 6.8-fold increased risk of sever...
Anne Cooke
Anne Cooke
CD4(+) T cells have been subdivided into different subsets, largely on the basis of the cytokines they produce. These subsets include Th1, Th2 and regulatory T cells. Recently, another population of T cells have been described, namely Th17,...
Can the Glycemic Index (GI) be used as a tool in the prevention and management of Type 2 diabetes? [0.03%]
glycemic index(GI)在2型糖尿病预防与管理中的作用及应用
Marie-Louise F Hermansen,Nina M B Eriksen,Lene S Mortensen et al.
Marie-Louise F Hermansen et al.
The large increase in type 2 diabetes (T2DM), the considerable lifetime risk of diabetes and the loss of lifetime call for concerted action to prevent T2DM and its complications. Since diabetes is characterized by abnormal glucose metabolis...
Antonella Puglianiello,Stefano Cianfarani
Antonella Puglianiello