"Low dose" metformin improves hyperglycemia better than acarbose in type 2 diabetics [0.03%]
低剂量二甲双胍优于阿卡波糖可更好地改善2型糖尿病患者的高血糖症状
Ken Yajima,Akira Shimada,Hiroshi Hirose et al.
Ken Yajima et al.
Objectives: "High dose" metformin therapy (2,550 mg/day) is reported to improve glycemic control in type 2 diabetic patients with obesity (body mass index (BMI) > or = 30). Some have reported that metformin therapy, even ...
Polyclonal anti-T-cell therapy for type 1 diabetes mellitus of recent onset [0.03%]
新发1型糖尿病的多克隆抗T细胞疗法
Frantisek Saudek,Tereza Havrdova,Petr Boucek et al.
Frantisek Saudek et al.
The destruction of pancreatic beta-cells in type 1 diabetes mellitus is mediated by autoreactive T-lymphocyte clones. We initiated a prospective randomized controlled trial of polyclonal rabbit anti-T-cell globulin (ATG) in patients with ty...
Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently [0.03%]
来源于选择性脱分化胰腺泡细胞的人胰导管上皮培养物表达受年龄依赖的肺发育基因1号基因(PDOX基因)
Cale N Street,Jonathan R T Lakey,Ray V Rajotte et al.
Cale N Street et al.
Adult pancreatic ductal cells are believed to be islet precursors. Our aim was to obtain an enriched human ductal cell population in defined culture conditions, and to characterize these cultures for the presence of pancreatic developmental...
Caterina Geremia,Stefano Cianfarani
Caterina Geremia
In the past decade, several epidemiological studies have shown a relationship between intrauterine growth retardation and insulin resistance, type 2 diabetes and cardiovascular disease in adulthood. Although the biological mechanisms underl...
Will C-peptide substitution make a difference in combating complications in insulin-deficient diabetes? [0.03%]
C-肽替代治疗能否改善胰岛素缺乏糖尿病患者的并发症？
Anders A F Sima
Anders A F Sima
Novel insights in the regulation of the immune system: a report on the FASEB summer research conference on autoimmunity (June 14-19, 2003, Saxton's River, Vermont, USA) [0.03%]
有关免疫系统调节的新认识：美国佛蒙特州塞克顿里弗FASEB自身免疫研究会议报告(2003年6月14日至19日)
Matthew A Gronski
Matthew A Gronski
The bi-annual FASEB autoimmunity conference organized last year by Betty Diamond and Stephen Miller brought together some 150 delegates studying various aspects of autoimmune diseases such as lupus, rheumatoid arthritis and autoimmune diabe...
Diagnosis and localization of insulinoma after negative laparotomy by hyperinsulinemic, hypoglycemic clamp and intra-arterial calcium stimulation [0.03%]
术前定位诊断胰岛素瘤的方法及意义
Robert A Ritzel,Berend Isermann,Tobias Schilling et al.
Robert A Ritzel et al.
A 40-year-old woman with recurrent episodes of hypoglycemia was referred because of suspected insulinoma. Prolonged fasting was discontinued after 24 h due to symptomatic hypoglycemia (29 mg/dl, glucose/insulin-ratio 0.34). Magnetic resonan...
Elimination of dietary gluten and development of type 1 diabetes in high risk subjects [0.03%]
无麸质饮食与高危个体1型糖尿病发病的关系
Martin Füchtenbusch,Anette-G Ziegler,Michael Hummel
Martin Füchtenbusch
Removal of dietary gluten is associated with a lower frequency of type 1 diabetes (T1D) in patients with celiac disease. Therefore, we performed a pilot study in which seven islet-antibody-positive first degree relatives of patients with T1...
Adherence to guidelines and its effects on hospitalizations with complications of type 2 diabetes [0.03%]
循证指南依从性与2型糖尿病住院并发症的影响关系研究
Frank A Sloan,M Angelyn Bethel,Paul P Lee et al.
Frank A Sloan et al.
Objectives: To study the discrepancy between actual and recommended rates of use among several measures of screening for complications of diabetes in a national longitudinal sample, the correlations among measures of adhe...
The association of silent coronary artery disease and metabolic syndrome in Chinese with type 2 diabetes mellitus [0.03%]
无症状冠心病与2型糖尿病合并代谢综合征的关联性研究
Jack C-R Tsai,Dao-Ming Chang,Fu-Mei Chung et al.
Jack C-R Tsai et al.
Objectives: Cardiovascular diseases account for approximately 75% of the deaths that occur in patients with diabetes. Because the clinical signs of coronary artery disease (CAD) in diabetic patients are hard to detect and...