New therapeutic strategies for the treatment of type 2 diabetes mellitus based on incretins [0.03%]
基于肠降糖激素的2型糖尿病治疗新策略
Baptist Gallwitz
Baptist Gallwitz
Orally ingested glucose leads to a greater insulin response compared to intravenously administered glucose leading to identical postprandial plasma glucose excursions, a phenomenon referred to as the "incretin effect". The incretin effect c...
Type 1 diabetes and NKT cells: a report on the 3rd International Workshop on NKT cells and CD1-mediated antigen presentation, September 2004, Heron Island, QLD, Australia [0.03%]
自然杀伤T细胞与I型糖尿病：第3届自然杀伤T细胞及CD1介导的抗原呈递国际研讨会报告（澳大利亚昆士兰州赫伦岛，2004年9月）
Julie M Fletcher,Margaret A Jordan,Alan G Baxter
Julie M Fletcher
NKT cells play a major role in regulating the vigor and character of a broad range of immune responses. Defects in NKT cell numbers and function have been associated with type 1 diabetes, especially in the NOD mouse model. The 3rd Internati...
Modulating the autoimmune response in type 1 diabetes: a report on the 64th scientific sessions of the ADA, June 2004, Orlando, FL, USA [0.03%]
自身免疫性糖尿病的免疫调节治疗：美国糖尿病学会2004年会报告
Peter Achenbach,Martin Füchtenbusch
Peter Achenbach
Type 1 diabetes mellitus results from a loss of insulin-producing beta-cells in the pancreatic islets caused by an immune-mediated chronic destructive process. It is generally believed that immune tolerance to beta-cells is broken by enviro...
Tailored immunosuppression and steroid withdrawal in pancreas-kidney transplantation [0.03%]
胰腺-肾脏移植的定制免疫抑制及激素撤药研究
Maura Rossetti,Giorgina B Piccoli,Manuel Burdese et al.
Maura Rossetti et al.
Background: Recent improvements in simultaneous pancreas-kidney transplantation (SPK) and the striking decrease in acute rejection lead us to focus on the effects of long-term immunosuppression. ...
Visceral obesity and hemostatic profile in patients with type 2 diabetes: the effect of gender and metabolic compensation [0.03%]
2型糖尿病患者内脏肥胖与凝血状况的关系及性别和代谢代偿的影响
Elzbieta Kozek,Barbara Katra,Maciej Malecki et al.
Elzbieta Kozek et al.
Background: Type 2 diabetes (T2DM) patients are characterized by a very high risk of cardiovascular diseases. Among the factors that are responsible for this phenomenon are abdominal obesity and hemostatic abnormalities. ...
Mucosal tolerance to prevent type 1 diabetes: can the outcome be improved in humans? [0.03%]
预防1型糖尿病的黏膜耐受：能否改善人类治疗效果？
Arno Hanninen,Leonard C Harrison
Arno Hanninen
The results of trials in which autoantigens have been fed to individuals affected by autoimmune diseases - multiple sclerosis, rheumatoid arthritis and type 1 diabetes - have been disappointing in terms of clinical improvement. This is in s...
Immunotherapy after recent-onset type 1 diabetes: combinatorial treatment for achieving long-term remission in humans? [0.03%]
新发I型糖尿病免疫治疗后的联合疗法可实现人类长期缓解吗？
Damien Bresson,Matthias von Herrath
Damien Bresson
Low-protein vegetarian diet with alpha-chetoanalogues prior to pre-emptive pancreas-kidney transplantation [0.03%]
低蛋白素食联合α-酮酸类化合物在胰肾预构移植术前的应用
Giorgina B Piccoli,Daria Motta,Guido Martina et al.
Giorgina B Piccoli et al.
Background: Pre-emptive pancreas-kidney transplantation is increasingly considered the best therapy for irreversible chronic kidney disease (CKD) in type 1 diabetics. However, the best approach in the wait for transplanta...