Association of postprandial hyperglycemia with in vitro LDL oxidation in non-smoking patients with type 1 diabetes--a cross-sectional study [0.03%]
餐后高血糖与1型糖尿病非吸烟患者的体外氧化低密度脂蛋白的相关性横断面研究
Simone H de Castro,Hugo C Castro-Faria-Neto,Marilia B Gomes
Simone H de Castro
Background: Cardiovascular disease is the main cause of death in patients with type 1 diabetes. Since oxidized low density lipoprotein (LDL) is considered to be a critical factor in the atherosclerotic process, the aim of...
Insulinotropic and anti-inflammatory effects of rosiglitazone in experimental autoimmune diabetes [0.03%]
罗格列酮对实验性自身免疫糖尿病的胰岛素增效和抗炎作用
Wageh M Awara,Alaa E el-Sisi,Mohamed el-Refaei et al.
Wageh M Awara et al.
Cytokines and nitric oxide (NO) are involved in the pathogenesis of autoimmune diabetes mellitus (DM). Rosiglitazone is an insulin-sensitizing drug that is a ligand for the nuclear receptor peroxisome proliferator-activated receptor-gamma (...
High-fat feeding during gestation and nursing period have differential effects on the insulin secretory capacity in offspring from normal Wistar rats [0.03%]
妊娠期和哺乳期高脂喂养对正常Wistar大鼠子代的胰岛素分泌能力有不同的影响
Stig E U Dyrskog,Søren Gregersen,Kjeld Hermansen
Stig E U Dyrskog
Restriction of protein or energy intake during gestation or early life is linked to developmental defects in the endocrine pancreas and insulin resistance. Aims: ...
F Susan Wong,Li Wen
F Susan Wong
Autoantibodies have been used as good markers for the prediction of future development of type 1 diabetes mellitus (T1DM), but are not thought to be pathogenic in this disease. The role of B cells that produce autoantibodies in the pathogen...
Questioning four preconceived ideas on immunotherapy of clinical type 1 diabetes: lessons from recent CD3 antibody trials [0.03%]
质疑关于临床1型糖尿病免疫治疗的四个先入为主的观念：最近针对CD3抗体试验的教训
Lucienne Chatenoud,Jean-François Bach
Lucienne Chatenoud
Charles Sia,Michael Weinem
Charles Sia
The use of DNA-based genetic typing has enabled the identification of type 1 diabetes mellitus (T1DM) susceptible and protective major histocompatibility complex (MHC) class II alleles and haplotypes. The application of this approach has al...
Cholesterol emboli syndrome in type 2 diabetes: the disease history of a case evaluated with renal scintigraphy [0.03%]
2型糖尿病患者胆固醇栓塞综合征的病例分析及肾动态显像表现回顾
Giorgina B Piccoli,Antonella Sargiotto,Manuel Burdese et al.
Giorgina B Piccoli et al.
Background: Cholesterol crystal emboli syndrome (CCE) is an emerging disease, whose progression reflects the currently observed increase in cardiovascular diseases. Diagnostic criteria shifted from pathological to clinica...
The diterpene glycoside, rebaudioside A, does not improve glycemic control or affect blood pressure after eight weeks treatment in the Goto-Kakizaki rat [0.03%]
Stevia 纯提取物雷博糖醇A无法改善GK糖尿病模型鼠的血糖或血压控制能力
Stig E U Dyrskog,Per B Jeppesen,Jianguo Chen et al.
Stig E U Dyrskog et al.
The plant, Stevia rebaudiana Bertoni (SrB), has been used for the treatment of diabetes in traditional medicine. Previously, we have demonstrated that long-term administration of the glycoside stevioside has insulinotropic, glucagonostatic,...
Increased transcriptional preproinsulin II beta-cell activity in neonatal nonobese diabetic mice: in situ hybridization analysis [0.03%]
新生小鼠非肥胖糖尿病小鼠胰岛β细胞中前 insulinII转录活性增强：原位杂交分析
Marc Throsby,Josiane Coulaud,Sylvie Durant et al.
Marc Throsby et al.
In the prediabetic nonobese diabetic (NOD) mouse, a spontaneous model of type 1 diabetes, we previously reported transient postweaning hyperinsulinemia followed by progressive islet hyperplasia. A modified in situ hybridization technique wa...
Manganese superoxide dismutase alanine to valine polymorphism and risk of neuropathy and nephropathy in Egyptian type 1 diabetic patients [0.03%]
埃及1型糖尿病患者中 manganese superoxide dismutase 谷氨酸到缬氨酸多态性与神经病变和肾病风险的关系
Tarek M el-Masry,Mona A M Abou Zahra,Mohammed M el-Tawil et al.
Tarek M el-Masry et al.
Oxidative stress, characterized by a marked increase in the level of oxygen free radicals (OFR), has been implicated in the development of diabetic microangiopathic complications, such as diabetic neuropathy (DN) and nephropathy (DP). Antio...