Hideaki Kaneto,Yoshihisa Nakatani,Dan Kawamori et al.
Hideaki Kaneto et al.
The hallmark of type 2 diabetes is pancreatic beta-cell dysfunction and insulin resistance. Normal beta-cells can compensate for insulin resistance by increasing insulin secretion, but insufficient compensation leads to the onset of glucose...
Differential roles of costimulatory signaling pathways in type 1 diabetes mellitus [0.03%]
I型糖尿病中协同刺激信号途径的不同作用
Bernhard O Boehm,Jeffrey A Bluestone
Bernhard O Boehm
The application of umbilical cord blood cells in the treatment of diabetes mellitus [0.03%]
胎盘血干细胞治疗糖尿病的应用研究进展
Tomas Koblas,S Mitchell Harman,Frantisek Saudek
Tomas Koblas
In recent years, human umbilical cord blood (HUCB) has emerged as an attractive tool for cell-based therapy. Although at present the clinical application of HUCB is limited to the fields of hematology and oncology, a rising number of studie...
Shell-less chick embryo culture as an alternative in vitro model to investigate glucose-induced malformations in mammalian embryos [0.03%]
无壳鸡胚培养作为体内模型研究哺乳动物胚胎糖类诱导畸形的替代方法
Savita Datar,Ramesh R Bhonde
Savita Datar
We have developed a simple shell-less chick embryo culture system to study glucose-induced malformations. This system involves the culturing of chick embryos from the second day to the fifth day of incubation, with associated yolk and thick...
Effect of losartan on the mRNA expressions of MT3-MMP and TIMP-2 in diabetic kidneys [0.03%]
洛沙坦对糖尿病肾脏MT3-MMP和TIMP-2的影响
He-Lin Ding,Ming-Tong Xu,Ying Guo et al.
He-Lin Ding et al.
Background and objectives: The renin-angiotensin system plays a critical role in circulatory homoeostasis. Evidence has emerged that suggests a pathologic role for angiotensin II in patients with kidney disease. Losartan ...
The relationship between dietary habits, blood glucose and insulin levels among people without cardiovascular disease and type 2 diabetes; the ATTICA study [0.03%]
无心血管疾病和2型糖尿病者膳食习惯与血糖、胰岛素水平之间的关系；雅典ATTICA研究
Demosthenes B Panagiotakos,Natalia Tzima,Christos Pitsavos et al.
Demosthenes B Panagiotakos et al.
Background: Diet has long been associated with a risk of insulin resistance and poor glycemic control. We sought to investigate the association between food groups and indices of glycemic control in adults without type 2 ...
Erik Biros,Margaret A Jordan,Alan G Baxter
Erik Biros
The relative risk of type 1 (autoimmune) diabetes mellitus for a sibling of an affected patient is fifteen times that of the general population, indicating a strong genetic contribution to the disease. Yet, the incidence of diabetes in most...
Limitations in immunotherapy with CD3 antibodies: comment on the article by Drs. Chatenoud and Bach [0.03%]
有关查坦杜和巴赫博士文章的评论：CD3抗体免疫治疗的局限性
Damien Bresson,Matthias von Herrath
Damien Bresson
Imbalance in Th cell polarization and its relevance in type 1 diabetes mellitus [0.03%]
T辅助细胞极化失衡及其在1型糖尿病中的意义
Charles Sia
Charles Sia
Functional polarization of T helper (Th) subsets of lymphocytes has been implicated in promoting or conferring risk to Type 1 diabetes mellitus (T1DM) development in human and diabetic animal models. It is assumed that an immoderate prepond...
Meenal Banerjee,Meghana Kanitkar,Ramesh R Bhonde
Meenal Banerjee
The phenomenon of pancreatic regeneration in mammals has been well documented. It has been shown that pancreatic tissue is able to regenerate in several species of mammal after surgical insult. This tissue is also known to have the potentia...