Impact of metabolic syndrome risk factors in first-degree relatives of type 2 diabetic patients [0.03%]
2型糖尿病患者一级亲属代谢综合征危险因素的影响
Susana Siewert,Sergio Filipuzzi,Leticia Codazzi et al.
Susana Siewert et al.
Objective: Family members of patients with an established diagnosis of type 2 diabetes mellitus (T2DM) are theoretically at risk of having the metabolic syndrome (MetS). A sample of these family members was studied from a...
Diabetes and impaired glucose regulation in first-degree relatives of patients with type 2 diabetes in isfahan, iran: prevalence and risk factors [0.03%]
伊朗伊斯法罕2型糖尿病患者一级亲属的糖尿病与葡萄糖调节受损的患病率及危险因素研究
Masoud Amini,Mohsen Janghorbani
Masoud Amini
Objectives: The aim of this study was to estimate the prevalence of diabetes, impaired glucose tolerance (IGT), and impaired fasting glucose (IFG) in first-degree relatives (FDR) of people with type 2 diabetes mellitus. ...
Diabetic Cardiomyopathy in OVE26 Mice Shows Mitochondrial ROS Production and Divergence Between In Vivo and In Vitro Contractility [0.03%]
链脲佐菌素致糖尿病OVEX26型转基因小鼠心肌细胞中活性氧的产生及体内、外收缩功能的差异性研究
Ye Song,Yibo Du,Sumanth D Prabhu et al.
Ye Song et al.
Many diabetic patients suffer from a cardiomyopathy that cannot be explained solely by poor coronary perfusion. This cardiomyopathy may be due to either organ-based damage like fibrosis, or to direct damage to cardiomyocytes. Mitochondrial-...
Expression Analysis of cPLA2 Alpha Interacting TIP60 in Diabetic KKAy and Non-Diabetic C57BL Wild-Type Mice: No Impact of Transient and Stable TIP60 Overexpression on Glucose-Stimulated Insulin Secretion in Pancreatic Beta-Cells [0.03%]
糖尿病KKAy和非糖尿病C57BL野生型小鼠TIP60与cPLA2 Alpha相互作用表达分析：短暂和稳定过表达TIP60对胰岛β细胞葡萄糖刺激的胰岛素分泌无影响
Iver Nordentoft,Per B Jeppesen,Anders L Nielsen et al.
Iver Nordentoft et al.
In the present study we investigate the expression levels of cytosolic phospholipase A2 alpha (cPLA2alpha) interacting histone acetyl transferase proteins TIP60alpha and TIP60beta in non-diabetic C57BL wild-type mice and obese type 2 diabet...
Adipose Tissue: A Metabolic Regulator. Potential Implications for the Metabolic Outcome of Subjects Born Small for Gestational Age (SGA) [0.03%]
脂肪组织：一个代谢调节器。对于胎龄小的婴儿出生后的代谢结果的影响的潜在作用
Arianna Maiorana,Chiara Del Bianco,Stefano Cianfarani
Arianna Maiorana
Adipose tissue is involved in the regulation of glucose and lipid metabolism, energy balance, inflammation and immune response. Abdominal obesity plays a key role in the development of insulin resistance because of the high lipolytic rate o...
DPP-4 Inhibitors and Combined Treatment in Type 2 Diabetes: Re-evaluation of Clinical Success and Safety [0.03%]
DPP-4抑制剂与2型糖尿病的联合治疗：临床疗效和安全性的再评价
Harold W de Valk
Harold W de Valk
The incretin system has proven to be a new source of glucose-lowering drugs. Glucon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) are the incretins which are degraded by dipeptidyl peptidase-4 (DPP-4). GLP-1 is t...
Increased Expression of Monocyte CD11b (Mac-1) in Overweight Recent-Onset Type 1 Diabetic Children [0.03%]
肥胖的一型糖尿病患儿近期发病单核细胞CD11b(Mac-1)表达增强
Vincenza Cifarelli,Ingrid M Libman,Angela Deluca et al.
Vincenza Cifarelli et al.
Aim: Compelling evidence implicates inflammation in the pathogenesis of type 1 diabetes mellitus (T1DM) and associated vascular complications. Obesity is also characterized by low-grade systemic inflammation. In this stud...
Long-term, moderate coffee consumption is associated with lower prevalence of diabetes mellitus among elderly non-tea drinkers from the Mediterranean Islands (MEDIS Study) [0.03%]
长期适度饮用咖啡与地中海岛屿地区老年人糖尿病患病率较低相关（MEDIS研究）
Demosthenes B Panagiotakos,Christos Lionis,Akis Zeimbekis et al.
Demosthenes B Panagiotakos et al.
Background: We evaluated the association between coffee drinking and the prevalence of type 2 diabetes mellitus in elderly people from the Mediterranean islands. ...
Association Between Low-Grade Systemic Inflammation and Type 2 Diabetes Mellitus Among Men and Women from the ATTICA Study [0.03%]
爱塔卡研究中低水平全身性炎症与2型糖尿病之间的关系：男性和女性的差异
Christos Pitsavos,Metaxia Tampourlou,Demosthenes B Panagiotakos et al.
Christos Pitsavos et al.
Aim: To investigate the relationship between low-grade inflammation and several glycemic indices in a population-based sample of men and women. Methods: ...
3-Month Results from Denmark within the Globally Prospective and Observational Study to Evaluate Insulin Detemir Treatment in Type 1 and Type 2 Diabetes: The PREDICTIVE Study [0.03%]
在1型和2型糖尿病患者中评价使用精蛋白重组人胰岛素类似物治疗的全球性前瞻性观察研究(PREDICTIVE研究)——丹麦3个月结果
Kjeld Hermansen,Per Lund,Kurt Clemmensen et al.
Kjeld Hermansen et al.
PREDICTIVEtrade mark is a large, multi-national, open-label, prospective, observational study to assess the efficacy and safety of insulin detemir in clinical practice. We report 3-month follow-up data from 389 patients with type 1 (n = 312...