Claire E Hills,Nigel J Brunskill
Claire E Hills
Although long believed to be inert, C-peptide has now been shown to have definite biological effects both in vitro and in vivo in diabetic animals and in patients with type 1 diabetes. These effects point to a protective action of C-peptide...
The relevance of C-Peptide in diabetes and its complications: an introduction to the special issue [0.03%]
C-肽在糖尿病及其并发症中的意义——特刊介绍
Anders A F Sima,John Wahren
Anders A F Sima
Prevalence of diabetic retinopathy and cataract in adult patients with type 1 and type 2 diabetes in Russia [0.03%]
俄罗斯1型和2型糖尿病成人患者糖尿病视网膜病变和白内障的患病率
Ivan Dedov,Oxana Maslova,Yurii Suntsov et al.
Ivan Dedov et al.
Aim: The aim of the study was to identify the prevalence of diabetic retinopathy (DR) and diabetic cataract (DC) in type 1 and type 2 diabetic patients within the Russian Federation. Also, the stage of DR at the time of i...
Comparison of fasting glucose with post-load glucose values and glycated hemoglobin for prediction of type 2 diabetes: the Isfahan diabetes prevention study [0.03%]
与空腹血糖和糖化血红蛋白相比,餐后血糖值在预测2型糖尿病方面的价值:伊斯法罕糖尿病预防研究
Mohsen Janghorbani,Masoud Amini
Mohsen Janghorbani
Objectives: The aim of this study was to compare the ability of fasting plasma glucose (FPG), post-load plasma glucose values and glycated hemoglobin (HbA1c) to predict progression to diabetes in non-diabetic first-degree...
Allelic variation of Ets1 does not contribute to NK and NKT cell deficiencies in type 1 diabetes susceptible NOD mice [0.03%]
Ets1等位基因多态性并非导致1型糖尿病易感小鼠NK和NKT细胞缺陷的原因
Margaret A Jordan,Lynn D Poulton,Julie M Fletcher et al.
Margaret A Jordan et al.
The NOD mouse is a well characterized model of type 1 diabetes that shares several of the characteristics of Ets1-deficient targeted mutant mice, viz: defects in TCR allelic exclusion, susceptibility to a lupus like disease characterized by...
Type 1 diabetes development requires both CD4+ and CD8+ T cells and can be reversed by non-depleting antibodies targeting both T cell populations [0.03%]
1型糖尿病的发展需要CD4+和CD8+t细胞,并且可以通过靶向这两种t细胞的非耗尽性抗体逆转
Jenny M Phillips,Nicole M Parish,Tim Raine et al.
Jenny M Phillips et al.
Type 1 diabetes development in NOD mice appears to require both CD4(+) and CD8(+) T cells. However, there are some situations where it has been suggested that either CD4(+) or CD8(+) T cells are able to mediate diabetes in the absence of th...
Ken T Coppieters,Matthias G von Herrath
Ken T Coppieters
Although our knowledge on the various aspects of diabetes development in the NOD mouse model is substantial and keeps expanding at a dramatic pace, the dataset on histopathologic features of type 1 diabetes (T1D) in patients remains largely...
Akira Shimada,Yoichi Oikawa,Yoshifumi Yamada et al.
Akira Shimada et al.
Despite intervention with insulin, type 1 diabetes gradually deteriorates the patients' quality of life. The disease is characterized by an immune-mediated destruction of pancreatic beta-cells. Its etiology, however, remains controversial. ...
William A Rudert,Massimo Trucco
William A Rudert
Inspired by the articles presented in this issue of The Review of Diabetic Studies, we considered it useful to summarize the latest achievements and current challenges we face in the search for a cure of type 1 diabetes. In this editorial a...
Effect of zinc supplementation on serum homocysteine in type 2 diabetic patients with microalbuminuria [0.03%]
锌补充对2型糖尿病微量白蛋白尿患者血清同型半胱氨酸的影响
Esfandiar Heidarian,Massoud Amini,Mahmoud Parham et al.
Esfandiar Heidarian et al.
Objectives: Elevated homocysteine levels are considered to be an independent risk factor for cardiovascular complications in diabetic patients. The aim of this study was to find out if zinc supplementation improves homocy...