First principles of terrestrial life: exemplars for potential extra-terrestrial biology [0.03%]
地球生命的原理：潜在地外生命的典范
Ian von Hegner
Ian von Hegner
The search for life elsewhere in the universe represents not only a potential expansion of our knowledge regarding life, but also a clarification of the first principles applicable to terrestrial life, which thus restrict the very search fo...
Thermodynamic principles for system biology and the patterns of flower pigmentation [0.03%]
系统生物学中的热力学原理及花瓣色素图案化现象分析
Qinyi Zhao
Qinyi Zhao
The thermodynamic principles for system biology are reviewed and formulated, and then basic patterns of flower pigmentation are interpreted. Main thoughts: (1) any biological trait (color or function of a cell) is logically related to a the...
Mathematical modeling for mutator phenotype and clonal selection advantage in the risk analysis of lung cancer [0.03%]
肺癌风险分析中耐药_mutator表型及克隆选择优势的数学模型研究
Lingling Li,Ting Zhao,Xingshi He et al.
Lingling Li et al.
Cancer is one of the leading diseases for human mortality. Although substantial research works have been conducted to investigate the initiation and progression of cancer disease, it is still an active debate regarding the function of mutat...
The historical nature of biological complexity and the ineffectiveness of the mathematical approach to it [0.03%]
生物学复杂性的历史性质及其数学方法的无效性
Saverio Forestiero
Saverio Forestiero
Contemporary scientific knowledge is built on both methodological and epistemological reductionism. The discovery of the limitations of the reductionist paradigm in the mathematical treatment of certain physical phenomena originated the not...
Network representation and analysis of energy coupling mechanisms in cellular metabolism by a graph-theoretical approach [0.03%]
基于图论方法的细胞代谢能量耦合机制的网络表征与分析
Sunil Nath
Sunil Nath
Mechanisms coupling the chemical reactions of oxidation and ATP synthesis in cellular metabolism by the fundamental biological process of oxidative phosphorylation (OX PHOS) in mitochondria provide > 90% of the energy requirements in living...
Luciano Boi
Luciano Boi
This paper is aimed at demonstrating that some geometrical and topological transformations and operations serve not only as promoters of many specific genetic and cellular events in multicellular living organisms, but also as initiators of ...
Alain Berthoz
Alain Berthoz
How much biology is in the product? Role and relevance of biological evolution and function for bio-inspired design [0.03%]
生物对于设计灵感有多重要？进化及功能在仿生学中的作用与意义分析
Anita Roth-Nebelsick
Anita Roth-Nebelsick
Bio-inspired design (BID) means the concept of transferring functional principles from biology to technology. The core idea driving BID-related work is that evolution has shaped functional attributes, which are termed "adaptations" in biolo...
Geometry and phenomenology of the living: Limits and possibilities of mathematization, complexity and individuation in biological sciences [0.03%]
几何与生命现象学：生物科学中数学化的限制与可能性、复杂性与个体化问题
Luciano Boi,Carlos Lobo
Luciano Boi
The central aim of this Special Issue, devoted to a multifocal study of the geometry and phenomenology of the living, is to show the need of working with models that integrate geometrical and topological objects and operations, dynamical va...