Symmetry breaking and mismatch in the torsional mechanism of ATP synthesis by FOF1-ATP synthase: mathematical number theory proof and its chemical and biological implications [0.03%]
FOF1-ATP合成酶的扭转机制中的对称破缺和错配：数学数论证明及其化学和生物学含义
Sunil Nath
Sunil Nath
Can mathematical proofs be employed for the solution of fundamental molecular-level problems in biology? Recently, I mathematically tackled complex mechanistic problems arising during the synthesis of the universal biological currency, aden...
Elena Fimmel,Hadi Saleh,Lutz Strüngmann
Elena Fimmel
Circular codes, which are considered as putative remnants of primaeval comma-free codes, have recently become a focal point of research. These codes constitute a secondary type of genetic code, primarily tasked with detecting and preserving...
A new symbiotic, holistic and gradualist model proposal for the concept of "living organism" [0.03%]
一种新的共生的整体论和渐进主义的“生物有机体”概念模型提案
Mirco Plante
Mirco Plante
In biology, the concept of "living organism" has traditionally been based on the smallest level of organization comprising all the necessary and essential characteristics of life: the cell. Today, this concept is being challenged by the ana...
Mathematical model of tumor immune microenvironment with application to the combined therapy targeting the PD-1/PD-L1 pathway and IL-10 cytokine antibody [0.03%]
一种肿瘤免疫微环境的数学模型及其在PD-1/PD-L1和IL-10抗体联合治疗中的应用
Zixin Zhang,Xiyin Liang,Jianyong Qin et al.
Zixin Zhang et al.
The tumor microenvironment constitutes a complex system shaped by the intricate interactions among tumor cells, immune cells, and cytokines. Within this environment, the interplay between immune cells and cytokines is crucial in influencing...
Jürgen Jost
Jürgen Jost
Bianca Y S Ishikawa,José F Fontanari
Bianca Y S Ishikawa
The conflict between individual and collective interests makes fostering cooperation in human societies a challenging task, requiring drastic measures such as the establishment of sanctioning institutions. These institutions are costly beca...
Hypothesis: bacteria live on the edge of phase transitions with a cell cycle regulated by a water-clock [0.03%]
假设：细菌生活在相变的边缘，其细胞周期由水钟调节
Vic Norris
Vic Norris
A fundamental problem in biology is how cells obtain the reproducible, coherent phenotypes needed for natural selection to act or, put differently, how cells manage to limit their exploration of the vastness of phenotype space. A subset of ...
Do concepts of individuality account for individuation practices in studies of host-parasite systems? A modeling account of biological individuality [0.03%]
个体化概念如何解释宿主-寄生关系研究中的个体化实践？一种生物学个体性的建模解释
Nina Kranke
Nina Kranke
In recent discussions, the widespread conviction that scientific individuation practices are governed by theories and concepts of biological individuality has been challenged, particularly by advocates of practice-based approaches. This dis...
Guillermo Restrepo
Guillermo Restrepo
In an effort to expand the domain of mathematical chemistry and inspire research beyond the realms of graph theory and quantum chemistry, we explore five mathematical chemistry spaces and their interconnectedness. These spaces comprise the ...
Eco-evolutionary dynamics of structured populations in periodically fluctuating environments: a G function approach [0.03%]
周期性波动环境中有向群体的生态进化动态：G函数方法
Anuraag Bukkuri
Anuraag Bukkuri
Understanding the ecological and evolutionary dynamics of populations is critical for both basic and applied purposes in a variety of biological contexts. Although several modeling frameworks have been developed to simulate eco-evolutionary...