Xin Zhang
Xin Zhang
Topological explanations in biology have been largely assumed to be free of mechanisms. However, by examining two classic topological explanations in the philosophical literature, this article has identified mechanisms in the corrected and ...
On biological individuation [0.03%]
论生物学上的个体性
Paul-Antoine Miquel,Su-Young Hwang
Paul-Antoine Miquel
In this paper, we understand the emergence of life as a pure individuation process. Individuation already occurs in open thermodynamics systems near equilibrium. We understand such open systems, as already recursively characterized (R1) by ...
Ingredients for robustness [0.03%]
鲁棒性的要素分析
Nihat Ay
Nihat Ay
A core property of robust systems is given by the invariance of their function against the removal of some of their structural components. This intuition has been formalised in the context of input-output maps, thereby introducing the notio...
Deryc T Painter,Frank van der Wouden,Manfred D Laubichler et al.
Deryc T Painter et al.
To what extent do simultaneous innovations occur and are independently from each other? In this paper we use a novel persistent keyword framework to systematically identify innovations in a large corpus containing academic papers in evoluti...
Rituparno Sen,Jörg Fallmann,Maria Emília M T Walter et al.
Rituparno Sen et al.
Many small nucleolar RNAs and many of the hairpin precursors of miRNAs are processed from long non-protein-coding host genes. In contrast to their highly conserved and heavily structured payload, the host genes feature poorly conserved sequ...
Marzieh Eidi,Amirhossein Farzam,Wilmer Leal et al.
Marzieh Eidi et al.
The relations, rather than the elements, constitute the structure of networks. We therefore develop a systematic approach to the analysis of networks, modelled as graphs or hypergraphs, that is based on structural properties of (hyper)edges...
Biological information [0.03%]
生物学信息
Jürgen Jost
Jürgen Jost
In computer science, we can theoretically neatly separate transmission and processing of information, hardware and software, and programs and their inputs. This is much more intricate in biology. Nevertheless, I argue that Shannon's concept...
Scientific traditions in conflict: the Rusconi-von Baer controversy on the embryology of frogs and the development of the cell theory [0.03%]
科学传统的冲突：Rusconi-von Baer关于蛙胚学和细胞理论发展的争论
Margherita Raineri,Erki Tammiksaar
Margherita Raineri
In 1835, the meaning of the cleavage furrows in the division of frog eggs was the cause of a heated argument between the Italian naturalist Mauro Rusconi and Karl Ernst von Baer. These furrows were first described by Prévost and Dumas (Ann...
Miled El Hajji
Miled El Hajji
A generalized model of intra-host CHIKV infection with two routes of infection has been proposed. In a first step, the basic reproduction number [Formula: see text] was calculated using the next-generation matrix method and the local and gl...
Hypothesis: nucleoid-associated proteins segregate with a parental DNA strand to generate coherent phenotypic diversity [0.03%]
假设：核质关联蛋白与亲本DNA链分离以产生一致的表型多样性
Yoan Konto-Ghiorghi,Vic Norris
Yoan Konto-Ghiorghi
The generation of a phenotypic diversity that is coherent across a bacterial population is a fundamental problem. We propose here that the DNA strand-specific segregation of certain nucleoid-associated proteins or NAPs results in these prot...