Diverse roles of glucocorticoids in the ruminant mammary gland: modulation of mammary growth, milk production, and mastitis [0.03%]
糖皮质激素在反刍动物乳腺中的多种作用：调节乳腺生长、产奶量和乳腺炎
Xiaoyue Ma,Hanling Liu,Qianqian Jia et al.
Xiaoyue Ma et al.
As endocrine hormones, glucocorticoids (GCs) play a pivotal role in numerous physiological processes, including mammary growth and lactation, circulatory metabolism, and responses to external stimuli. In the dairy industry, milk production ...
Norepinephrine promotes neuronal apoptosis of hippocampal HT22 cells by up-regulating the expression of long non-coding RNA MALAT1 [0.03%]
去甲肾上腺素通过上调长链非编码RNA-MALAT1表达促进海马HT22神经元凋亡
Ying Wang,Hui Hu,Yuhan Wu et al.
Ying Wang et al.
Stress is ever present in our modern, performance-oriented and demanding society, which causes adverse stress reactions of the body and affects health seriously. Chronic stress has been recognized as a significant risk factor leading to cog...
Early life adversity ablates sex differences in active versus passive threat responding in mice [0.03%]
早期生活压力会消除小鼠在主动威胁应对与被动威胁应对方面的性别差异
Gabriela Manzano Nieves,Marilyn Bravo,Kevin G Bath
Gabriela Manzano Nieves
Early life adversity (ELA) heightens the risk for anxiety disorders (which are characterized by heightened fear and avoidance behaviors), with females being twice as likely as males to develop pathology. Pavlovian fear conditioning tasks ha...
Edo Ronald de Kloet
Edo Ronald de Kloet
As the end product of the hypothalamus-pituitary-adrenal (HPA) axis, the glucocorticoid hormones cortisol and corticosterone coordinate circadian activities, stress-coping, and adaptation to change. For this purpose, the hormone promotes en...
Female rats are more responsive than are males to the protective effects of voluntary physical activity against the behavioral consequences of inescapable stress [0.03%]
与不可控压力的行为后果相比，自愿体力活动对雌性大鼠比雄性大鼠有更积极的影响
Margaret K Tanner,Alyssa A Hohorst,Simone M Mellert et al.
Margaret K Tanner et al.
Common stress-related mental health disorders affect women more than men. Physical activity can provide protection against the development of future stress-related mental health disorders (i.e. stress resistance) in both sexes, but whether ...
David Tuck,Joshua Wiley,Lefteris Patlamazoglou et al.
David Tuck et al.
Mental illnesses are the greatest health problems faced by younger people. As a group, tertiary education students demonstrate higher levels of distress than their age matched peers who are not tertiary students, making them an at-risk grou...
Examination of the role of adrenergic receptor stimulation in the sensitization of neuroinflammatory-based depressive-like behavior in isolated Guinea pig pups [0.03%]
去甲肾上腺素能受体在刺激神经炎症为基础的行为模型中的作用考察
Rachel R Kessler,Patricia A Schiml,Sean M McGraw et al.
Rachel R Kessler et al.
Early-life attachment disruption appears to sensitize neuroinflammatory signaling to increase later vulnerability for stress-related mental disorders, including depression. How stress initiates this process is unknown, but studies with adul...
Psychological, endocrine and polygenic predictors of emotional well-being during the COVID-19 pandemic in a longitudinal birth cohort [0.03%]
基于纵向出生队列在COVID-19大流行期间预测情绪幸福感的心理学、内分泌和多基因因素
Thao Nguyen,Lea Zillich,Metin Cetin et al.
Thao Nguyen et al.
The COVID-19 pandemic severely affected the lives of families and the well-being of both parents and their children. Various factors, including prenatal stress, dysregulated stress response systems, and genetics may have influenced how the ...
Burnout among high school students is linked to their telomere length and relatedness with peers [0.03%]
高中生的耗竭与端粒长度和同伴关系有关
Frances Hoferichter,Armin Jentsch,Lou Maas et al.
Frances Hoferichter et al.
School burnout is a serious concern, as it impairs students' health and academic success. According to the Conservation of Resources Theory, burnout results from the depletion of personal coping resources and can be counteracted by supporti...
Multiple brain regions are involved in reaction to acute restraint stress in CYLD-knockout mice [0.03%]
CYLD基因敲除小鼠应对急性束缚压力的多脑区参与反应
Yuan-Yuan Han,Jian-Wen Zhou,Zhi-Wei Guo et al.
Yuan-Yuan Han et al.
The lysine 63 deubiquitinase cylindromatosis (CYLD) is expressed at high levels in the brain and is considered to be involved in anxious and depressive behavior, cognitive inflexibility, and autism disorders. Previous research was limited i...