"Unravelling the Shared Genetic Architecture between Suicidality and Subcortical Brain Volume: A Genome-Wide Association Study" [0.03%]
“解开自杀倾向和皮质下脑体积之间的共同遗传结构:一项全基因组关联研究”
Joel Defo,Raj Ramesar
Joel Defo
Objective: Suicidality is a significant public health concern, with neuroimaging studies revealing abnormalities in the brains of suicidal individuals and post-mortem samples. However, the genetic architecture between sui...
Application of cognitive behavioral therapy combined with aripiprazole in the treatment of schizophrenia: a randomized controlled trial [0.03%]
认知行为疗法联合阿立哌唑治疗精神分裂症的临床应用:随机对照研究
Jun Yan,Kunjie Li,Qiang He et al.
Jun Yan et al.
Objective: This study focused on the effect of the cognitive behavioral therapy (CBT) combined with aripiprazole on cognitive functions and psychological state of schizophrenia patients. ...
Systematic Review of Differentially Abundant Proteins in People with Lewy Body Dementia [0.03%]
路易体痴呆患者差异表达蛋白的系统评价
Laura M Farr,Naomi Thorpe,Ethel M Brinda et al.
Laura M Farr et al.
Objectives: Dementia with Lewy Bodies (DLB) and Parkinson's Disease Dementia (PDD) are collectively called as Lewy body dementia (LBD). Despite the urgent clinical need, there is no reliable protein biomarker for LBD. Hen...
The immune checkpoint pathophysiology of depression and chronic fatigue syndrome due to preeclampsia: focus on sCD80 and sCTLA-4 [0.03%]
子痫导致的抑郁症和慢性疲劳综合征的免疫检查点病理生理机制:重点讲述可溶性CD80和可溶性细胞毒T淋巴细胞相关抗原4
Jangir Sami Omar,Niaz Albarzinji,Mengqi Niu et al.
Jangir Sami Omar et al.
Background: Neuropsychiatric disorders in preeclampsia (PE) women are prevalent and worsen PE outcome. Immune-related biomarkers including soluble sCD80 and cytotoxic T-lymphocyte antigen-4 (sCTLA-4) are not well studied ...
Influence of CYP2D6 phenotype on adherence, adverse effects, and attitudes in aripiprazole and risperidone users [0.03%]
细胞色素2D6基因型对使用阿立哌唑和利培酮患者依从性、不良反应及态度的影响
Elina Hietala,Anssi Solismaa,Markku Lähteenvuo et al.
Elina Hietala et al.
Background: Non-adherence and negative attitudes towards medication are major problems in treating psychotic disorders. Cytochrome P450 2D6 (CYP2D6) contributes to the metabolism of aripiprazole and risperidone. Variation...
Marina A M Portes,Isabel Werle,Leandro J Bertoglio
Marina A M Portes
Growing evidence suggests that psychedelic-assisted therapies can alleviate depression, anxiety, posttraumatic stress, and substance use disorder, offering relatively safe profiles, enhanced efficacy, and lasting effects after a few applica...
Evaluating the Safety Profile of Connectome-Based Repetitive Transcranial Magnetic Stimulation [0.03%]
基于连接组的重复经颅磁刺激的安全性评估
Si Jie Tang,Jonas Holle,Emil Gabrielsson et al.
Si Jie Tang et al.
Objective: New developments in neuro-navigation and machine learning have allowed for personalized approaches to repetitive transcranial magnetic stimulation (rTMS) to treat various neuropsychiatric disorders. One specifi...
The genetic association between major depressive disorder and coronary heart disease [0.03%]
主要抑郁障碍和冠心病的遗传关联性研究
Yue Shi,Feikang Xu,Yumei Wei et al.
Yue Shi et al.
Major depressive disorder (MDD) and coronary heart disease (CHD) can both cause significant morbidity and mortality. The association of MDD and CHD has long been identified, but the mechanisms still require further investigation. Seven mRNA...
Comorbid cerebrovascular and neurodegenerative burden in mild behavioral impairment and their impact on clinical trajectory [0.03%]
轻微行为障碍中并发的脑血管和神经退行性负担及其对临床轨迹的影响
Cheuk Ni Kan,Saima Hilal,Xin Xu et al.
Cheuk Ni Kan et al.
Aim: Mild behavioral impairment (MBI) is a neurobehavioral prodrome to dementia with multiple phenotypic characteristics. To investigate the complex neurobiological substrate underlying MBI, we evaluated its association w...
Selective serotonin reuptake inhibitors (SSRIs) and osteoporosis: A target trial emulation using real-world data [0.03%]
选择性5-羟色胺再摄取抑制剂(SSRI)与骨质疏松症:利用现实世界数据的目标试验仿真研究
Christopher Rohde,Lana J Williams,Michael Berk et al.
Christopher Rohde et al.
Objectives: Selective serotonin reuptake inhibitors (SSRIs) have been associated with increased risk of osteoporosis, and sertraline may be more potent than citalopram in this regard. Here, target trial emulation was used...