MR spectroscopic imaging and its association with EEG, CSF, and psychometric/neuropsychological findings in patients with suspected autoimmune psychosis spectrum syndromes [0.03%]
疑似自身免疫性精神病谱系综合征患者的磁共振波谱成像及其与脑电图、脑脊液和心理/神经心理学测量结果之间的关系研究
Dominique Endres,Isabelle Matteit,Katharina von Zedtwitz et al.
Dominique Endres et al.
Introduction: Autoimmune psychosis (AP) and other autoimmune psychiatric syndromes (APS) are associated with central nervous system antibodies. This study investigated related magnetic resonance spectroscopic imaging (MRS...
Transcriptomic and proteomic analyses of SH-SY5Y neuroblastoma cells treated with amisulpride [0.03%]
阿米舒普林处理的SH-SY5Y神经母细胞瘤细胞的转录组和蛋白质组分析
Tsung-Ming Hu,Hsin-Yao Tsai,Shih-Hsin Hsu et al.
Tsung-Ming Hu et al.
Objective: Amisulpride, a substituted benzamide derivative, has a unique pharmacological profile characterized by a high affinity for dopaminergic D2/D3 receptors, as well as an affinity for 5-HT7 receptors. Its effective...
Xanomeline-Trospium: Defining its Place Among the Current Antipsychotic Landscape [0.03%]
Xanomeline-曲司氯铵：在当前抗精神病药物领域的定位
Sajitha Nair,Sukhi Shergill,Eromona Whiskey
Sajitha Nair
Progress in the development of new and improved medications for psychosis has been notably slow and disappointing. The first treatment for schizophrenia was introduced in early 1950s and the majority of medications available today exclusive...
Exploring the Effects of Psilocybin on Depression and the Mediating Role of the 5-HT2A Receptor: A Systematic Review [0.03%]
裸头素治疗抑郁症及其五羟色胺2A受体介导作用的系统评价研究进展
Filipe Reis Teodoro Andrade,Tobias Buchborn,Gabriel Thalheimer et al.
Filipe Reis Teodoro Andrade et al.
Background: Major depressive disorder (MDD) is a significant public health concern, and current treatments often have limitations in effectiveness and adherence. Psilocybin, a psychedelic compound found in certain mushroo...
Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Opioid Use Disorders: A Systematic Review [0.03%]
胰高血糖素样肽-1受体激动剂治疗阿片类药物使用障碍的系统评价
Hezekiah C T Au,Pak Ho Lam,Fateen Kabir et al.
Hezekiah C T Au et al.
Voice as Objective Biomarker of Stress: Association of Speech Features and Cortisol [0.03%]
语音作为压力的客观生物标记物：言语特征与皮质醇之间的关联研究
Felix Menne,Hali Lindsay,Johannes Tröger et al.
Felix Menne et al.
Objective: Cortisol is a well-established biomarker of stress, assessed through salivary or blood samples, which are intrusive and time-consuming. Speech, influenced by physiological stress responses, offers a promising n...
The tryptophan catabolite pathway in major and simple neurocognitive psychosis: a double-edged sword with two sharpened edges [0.03%]
色氨酸降解途径在主要精神病和简单型精神分裂症中的双重作用
Hussein Kadhem Al-Hakeim,Ameer Abdul Razzaq Al-Issa,Chen Chen et al.
Hussein Kadhem Al-Hakeim et al.
Objectives: There are differences in IgA responses to tryptophan catabolites (TRYCATs) in major neurocognitive psychosis (MNP) versus simple neurocognitive psychosis (SNP) and normal controls. MNP and SNP are distinct sch...
Investigation of serum galanin, alarin, meteorin-like protein, and ischemia modified albumin levels in patients with schizophrenia [0.03%]
精神分裂症患者血清胃泌素、alarin、meteorin样蛋白及缺血修饰白蛋白水平的检测研究
Ozlem Gul,Huseyin Fatih Gul,Zozan Parsanoglu et al.
Ozlem Gul et al.
Objective: The objective of the current research is to study the serum levels of ischemia modified albumin (IMA), a new oxidative stress indicator, and various peptides (galanin, alarin, and meteorin-like protein) that ma...
C-reactive protein is not a biomarker of depression severity in drug-naïve obese patients with metabolic syndrome [0.03%]
C-反应蛋白不是代谢综合征肥胖且未服药患者的抑郁严重程度的生物标志物
Abbas F Almulla,Spas Kitov,Tanya Deneva et al.
Abbas F Almulla et al.
Background: Metabolic syndrome (MetS) is highly prevalent among adults and is frequently accompanied by depressive symptoms. While high-sensitivity C-reactive protein (hsCRP) has been proposed as a potential indicator of ...
Genetic correlation and causal relationships between autoimmune thyroid disease and major depressive disorders [0.03%]
自身免疫性甲状腺疾病和主要抑郁障碍的遗传相关性和因果关系
Yang Yu,Yingshuo Zhong,Yingzi Chen et al.
Yang Yu et al.
Background: Autoimmune thyroid disease (AITD) and major depressive disorder (MDD) are common genetic diseases. The comorbidity of AITD and MDD has been widely demonstrated by large amounts of epidemiological studies. Howe...