The Effect of GLP-1 Receptor Agonists on Autophagy: Insights Gathered from Research Evaluating Neurodegenerative Disorders With These Agents [0.03%]
GLP-1受体激动剂对自噬的影响：来自使用这些药物评估神经退行性疾病的研究的见解
Maria-Christina Sioufi,Isabela Heroiu,Sabrina Wong et al.
Maria-Christina Sioufi et al.
Objective: Impaired autophagy has been implicated in the pathophysiology of neurodegenerative disorders, such as Alzheimer's Disease (AD) and Parkinson's Disease (PD). Consistent and replicated evidence indicate that Gluc...
Predicting the need for electroconvulsive therapy via machine learning trained on electronic health record data [0.03%]
基于电子健康记录数据的机器学习预测电休克治疗需求
Lasse Hansen,Jakob Grøhn Damgaard,Robert M Lundin et al.
Lasse Hansen et al.
Objectives: Electroconvulsive therapy (ECT) is an effective treatment of severe manifestations of mental illness. Since delay in initiation of ECT can have detrimental effects, prediction of the need for ECT could improve...
Neurorestorative Properties of Ibogaine: Linking Multi-Receptor Affinities to Remyelination and Metabolic Restoration [0.03%]
伊博加因的神经修复特性：多受体亲和力与脱髓鞘及代谢恢复之间的联系
Tanya Calvey,Demi Govender,Gavin Owen et al.
Tanya Calvey et al.
Ibogaine is a psychedelic alkaloid without an approved indication. Observational clinical research shows linkages between single administration of ibogaine and relief of symptoms of neuropsychiatric conditions including substance use disord...
Investigation of leptin and leptin receptor gene polymorphisms in schizophrenia: further support for an association with attempted suicide [0.03%]
瘦素和瘦素受体基因多态性在精神分裂症中的研究：对自杀未遂相关性的进一步支持
Hasan Mervan Aytac,Yasemin Oyaci,Eren Aytac et al.
Hasan Mervan Aytac et al.
Objective: This study aimed to investigate leptin (LEP) (G-2548A) and leptin receptor (LEPR) (668A>G) gene polymorphisms in SCZ patients with and without suicide attempts, compared to controls. ...
Music and Binaural Beat Interventions for Young Adults: A Systematic Review of Effects on Anxiety, Sleep, and Cognition [0.03%]
针对年轻人的音乐与双耳效应干预措施对减轻焦虑、改善睡眠和认知作用的系统性综述
Hesham Y Elnazer
Hesham Y Elnazer
Background: Young adults (19-24 years) commonly experience elevated rates of sleep disturbance, anxiety, and cognitive stress yet often underutilise formal mental-health services. Music therapy, binaural beats, and relate...
Aspirin and Atorvastatin Augmentation Treatment in Patients with Major Affective Disorders and Inflammatory Dysregulation: A 12-Week Randomized Placebo-Controlled Study [0.03%]
水杨酸和阿托伐他汀对伴发炎性调节异常的重症情感障碍患者的增效治疗：一项12周随机双盲安慰剂对照研究
Ya-Mei Bai,Ju-Wei Hsu,Ying-Jay Liou et al.
Ya-Mei Bai et al.
Background: This study investigated whether aspirin and atorvastatin provide additional antidepressant effects in patients with major affective disorders and inflammatory dysregulation. ...
Functional Shotgun Metagenomic Insights into Gut Microbial Pathway and Enzyme Disruptions Linking Metabolism, Affect, Cognition, and Suicidal Ideation in Major Depressive Disorder [0.03%]
功能性代谢组学揭示肠道微生物途径和酶的破坏将新陈代谢、情绪、认知与重大抑郁障碍中的自杀念头联系起来
Michael Maes,Abbas F Almulla,Asara Vasupanrajit et al.
Michael Maes et al.
Background: Major depression (MDD) is linked to neuro-immune, metabolic, and oxidative stress (NIMETOX) pathways. The gut microbiome may contribute to these pathways via leaky gut and immune-metabolic processes. ...
A Dual-Marker Peripheral Signature of IL-6 Elevation and NEAT1 Reduction in Negative-Symptom Schizophrenia: A Cross-Sectional Study [0.03%]
一项横断面研究：在精神分裂症阴性症状患者中IL-6升高和NEAT1降低的双重外周标志物信号
Cosmin-Ioan Moga,Paul-Adrian Chiroi,Livia Budișan et al.
Cosmin-Ioan Moga et al.
Background: Schizophrenia (SCZ) shows marked biological heterogeneity, with negative symptoms linked to poor outcomes and hypothesized immune dysregulation. This study examined whether a peripheral cytokine-long non-codin...
Behavioural Addiction and Associated Risk Factors Among High School Students [0.03%]
高中生的行为成瘾及其相关危险因素
İbrahim Zeyrek,Muhammed Fatih Tabara,Mahmut Çakan et al.
İbrahim Zeyrek et al.
Objective: Investigating the relationship between behavioral addictions and mental health is essential due to their impact on well-being and the significant barriers they create to achieving lasting recovery. The aim of t...
Differences in Verbal Memory, Visuospatial Ability, and Cognitive Inhibition Among Young Women Using Drospirenone and Ethinyl Estradiol Oral Contraceptives Versus Naturally Cycling Controls [0.03%]
左洛孕酮和乙炔雌二醇口服避孕药使用者与自然月经周期对照组青年女性的语言记忆、视觉空间能力和认知抑制差异性研究
Natalia Lagunas,Laura Sánchez-Giraldo,Daniela Grassi et al.
Natalia Lagunas et al.
Objective: this study aimed to investigate the differences on cognitive performance across four cognitive domains-verbal memory, language fluency, visuospatial ability, and cognitive inhibition- between drospirenone and e...