Autologous Bone for Periodontal and Craniofacial Regeneration: Donor Sites, Characteristics and Indications [0.03%]
自体骨在牙周及颅面再生中的应用：取骨部位、特性及指征
David Palombo,Julia Ríos-Barbero,Tommaso Conforti et al.
David Palombo et al.
After decades of clinical use, autogenous bone continues to represent the gold standard material for promoting hard tissue regenerative processes in oral and craniofacial reconstructive interventions. This status is attributed to its robust...
Biological Principles for Success in Alveolar Bone, Soft Tissue, and Periodontal Regeneration [0.03%]
肺泡骨、软组织及牙周组织再生成功的生物学原理
Jessica Latimer,David T Wu,Birtan T Yilmaz et al.
Jessica Latimer et al.
Oral tissue regeneration involves the orchestration of known physiologic wound healing processes to synthesize single or composite tissues with functional, anatomical interfaces. Fundamental to oral tissue regeneration are the four main sta...
Tooth Movement Modulation and Root Protection via Piezo1-Mediated Production of Superoxide Dismutase 3 [0.03%]
Piezo1介导的超氧化物歧化酶3生成在牙齿移动调节和根保护中的作用
Xiaomeng Dong,Yujie Zhu,Bin Li et al.
Xiaomeng Dong et al.
Aims: This study investigated the role of superoxide dismutase 3 (SOD3) in alveolar bone remodeling and cementum repair under orthodontic loading. Methods...
Durumamide A Inhibits NLRP3 Assembly, Limiting Pro-Inflammatory Signaling in Human Gingival Fibroblasts [0.03%]
durumamide A 抑制NLRP3聚合限制人龈成纤维细胞中促炎信号转导
Jiyeon Park,Munseon Lee,In Hyun Hwang et al.
Jiyeon Park et al.
This study elucidates a potential mechanistic pathway by which DAA attenuates IL-1β secretion in HGF-1 cells, through the disruption of NLRP3 inflammasome assembly, thereby highlighting a novel anti-inflammatory property of DAA at the mole...
Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next-Generation Biomaterials [0.03%]
牙周和颅面再生中的水凝胶：当前应用及下一代生物材料
Z Gouveia,M Diba,B T Yilmaz et al.
Z Gouveia et al.
Periodontal and craniofacial tissue defects are complex regenerative targets as the reconstitution of tissue heterogeneity, interconnection and function is essential for favorable clinical outcomes. Periodontal tissues are additionally chal...
Extracellular Vesicles in Gingival Crevicular Fluid as Indicators of Periodontitis and Early Response to Non-surgical Periodontal Therapy [0.03%]
龈沟液中的细胞外囊泡作为牙周炎的标志物及非手术牙周治疗早期反应的指示物
Pingping Han,Andrew Liaw,Akila Suboda Vithanage et al.
Pingping Han et al.
Our study aims to profile EV subtypes and cytokines (IL-4, IL-10, IL-1β, TNF-α) across (1) shallow pockets (≤ 3 mm) in healthy, gingivitis, and periodontitis patients, and (2) deep pockets (≥ 6 mm) in periodontitis patients before and 1...
Matrix Metalloproteinases in Periodontal and Peri-Implant Diseases: Contribution to Their Pathogenesis, Diagnosis, and Treatment [0.03%]
基质金属蛋白酶与牙周病和种植体周围病的发病、诊断及治疗关系的研究进展
Timo Sorsa,Lorne M Golub,Julie Toby Thomas et al.
Timo Sorsa et al.
Matrix metalloproteinases (MMPs) represent a family of 23 zinc-dependent endopeptidases central to extracellular matrix remodeling in periodontal and peri-implant diseases. This comprehensive review examines the pathogenic mechanisms, diagn...
Rafael Scaf de Molon,Joao Paulo Steffens,Erica Dorigatti de Avila et al.
Rafael Scaf de Molon et al.
Periodontitis is a chronic, host-mediated inflammatory disease in which microbial dysbiosis and dysregulated immune responses drive the destruction of tooth-supporting tissues. Although conventional therapy remains centered on mechanical bi...
SIGIRR Inhibits Periodontitis-Associated Inflammation and Promotes Regeneration by Blocking Sp1 Nuclear Translocation [0.03%]
SIGIRR通过抑制Sp1核转位抑制牙周炎相关炎症并促进组织再生
Xuanxuan Yang,Weixu Li,Lizi Jin et al.
Xuanxuan Yang et al.
Aim: To investigate the contribution of the Single Immunoglobulin Interleukin-1 Receptor-Related Molecule (SIGIRR), a recently described negative mediator of inflammation signaling, in experimental periodontitis pathogene...
30 Years of Enamel Matrix Derivative (EMD): Biological Foundations and Systematic Review With Meta-Analyses Across Multiple Clinical Indications [0.03%]
玻璃离子类生物陶瓷材料研究三十年——生物学基础与多适应证系统评价及Meta分析
Richard J Miron,Nima Farshidfar,Yu-Kang Tu et al.
Richard J Miron et al.
Aim: Enamel matrix derivative (EMD) has been utilized in periodontology for over 30 years to promote periodontal tissue regeneration by mimicking key biological processes of root development. Preclinical studies confirmed...