Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro-Inflammatory Bias [0.03%]
牙周病患者在接受治疗后的巨噬细胞表型变化表明存在促炎倾向
Mariane Cristina Sloniak,Josiane Betim de Assis,Luciana Saraiva et al.
Mariane Cristina Sloniak et al.
Aim: Understanding macrophage polarization in periodontitis is critical for elucidating the underlying disease mechanisms. This exploratory study aimed to characterize phenotypic features of monocyte-derived macrophages (...
Study Design in Clinical and Epidemiologic Research: Observational, Experimental, and Beyond [0.03%]
临床和流行病学研究中的研究设计：观察性、实验性和超越性研究设计
Gustavo G Nascimento,Ignacio Leiva-Escobar,Maria Clotilde Carra et al.
Gustavo G Nascimento et al.
Population-based epidemiology and clinical research are complementary and mutually reinforcing: Epidemiology quantifies disease incidence/prevalence and elucidates environmental and social determinants in populations, whereas clinical resea...
Diagnosing and Treating Periodontitis and Multimorbidity Altogether: The Case Example of the Physical Exercise Hormone Irisin [0.03%]
兼顾牙周病和多重慢性疾病进行诊治的案例分析——以运动激素irisin为例
Larysa Saboya Cavalotti Perdonsini,Rafael Scaf de Molon,Søren Jepsen et al.
Larysa Saboya Cavalotti Perdonsini et al.
Irisin is an extracellular peptide stimulated by exercise and could act as both a biomarker and mediate the positive impact of exercise. This scoping review synthesizes human evidence on irisin variations in non-communicable diseases, showi...
Target Trial Emulation in Observational Research-Strengths, Limitations, and Methodological Considerations [0.03%]
目标试验模拟在观察性研究中的优势、局限性和方法学考虑因素
Sebastian-Edgar Baumeister,Ignacio Leiva-Escobar,Ryan T Demmer et al.
Sebastian-Edgar Baumeister et al.
Cohort studies are vulnerable to confounding and time-related biases. Recent advances emphasize the importance of emulating a hypothetical target trial to minimize several of these biases. The target trial framework is a critical tool for d...
MMP-8 in Peri-Implantitis: A Cross-Sectional Study on Genetic Polymorphisms and Enzymatic Activation [0.03%]
关于巨噬细胞迁移抑制因子-8在牙种植体周炎中多态性及酶活化作用的横断面研究
Ioannis Fragkioudakis,Christine Kottaridi,Michalis Paraskeva et al.
Ioannis Fragkioudakis et al.
This graphical abstract illustrates a molecular cascade linking MMP-8 gene polymorphism (-799C/T), upregulated mRNA expression in peri-implant crevicular fluid, and elevated active MMP-8 protein levels. These factors were independently asso...
Diet Quality as a Mediator Linking Tooth Loss and Cardiovascular Diseases in Older Adults [0.03%]
牙齿缺失与心血管疾病之间关系的中介作用：老年人群中的饮食质量介导效应分析
Ashish C Kalhan,Tosha A Kalhan,Marco A Peres et al.
Ashish C Kalhan et al.
Drawing on a large, nationally representative population of older American adults (n = 3610), the study shows that individuals with more than eight missing teeth have a 6%-10% higher likelihood of cardiovascular disease compared with those ...
Autogenous Demineralized Dentin Graft-Based Strategies With or Without I-PRF and Metronidazole for Ridge Preservation in Infected Sockets: A Randomized Clinical Trial [0.03%]
自体脱矿牙本质基质联合或不联合I-PRF和灭滴灵用于感染牙槽窝的牙槽嵴保存：随机临床试验
Mohamed Talaat Elbehwashy,Manal Mohamed Hosny,Ahmed Elfana et al.
Mohamed Talaat Elbehwashy et al.
Aim: This pilot randomized controlled trial evaluated the efficacy of demineralized dentin graft (DDG) combined with injectable platelet-rich fibrin (I-PRF) and metronidazole (MTZ) versus DDG with I-PRF and DDG alone in a...
Håvard Jostein Haugen,Javier Sanz,Giuseppe Perale et al.
Håvard Jostein Haugen et al.
Bone substitute biomaterials have become a sine qua non in periodontology and implant dentistry; however, the ideal material choice remains controversial. In this review, we examine natural grafts (autograft, allograft, xenograft) and synth...
The Natural History of Periodontitis in Man: The Past, the Present, the Future [0.03%]
牙周炎的自然史：过去、现在和未来
Ubele van der Velden,Monique M Danser
Ubele van der Velden
Peri-Implant Soft-Tissue Phenotype Modification for Refractory Peri-Implant Mucositis: A 12-Month Prospective Clinical Study With Ultrasonographic Analysis [0.03%]
声学分析辅助的黏膜炎治疗：为期12个月的临床研究
Shayan Barootchi,Lorenzo Tavelli,Hamoun Sabri et al.
Shayan Barootchi et al.
Aim: This prospective observational study evaluated the clinical, ultrasonographic, and patient-reported (PROMs) outcomes following surgical treatment of refractory/recurrent peri-implant mucositis (PM) using implant deco...