Stage-Associated Subgingival Dysbiosis Across the Periodontal Disease Spectrum in a Thai Cohort [0.03%]
泰国队列中整个牙周疾病谱的分期相关龈下菌群失调
Teerat Sawangpanyangkura,Kanokphong Suparan,Chanyanuch Wechwithayakhlung et al.
Teerat Sawangpanyangkura et al.
Aims: This cross-sectional study aimed to investigate the subgingival microbiota and predict functional profiles across the 2018 EFP/AAP periodontal disease spectrum in a Thai clinical cohort. ...
Long-Term Outcomes of 6-mm Short Implants Supporting Splinted Crowns in Posterior Regions: A 12-Year Prospective Multi-Centre Single-Cohort Study [0.03%]
支持后牙区连接桥的6mm短种植体长期疗效：一项为期12年的前瞻性多中心单队列研究
Diyuan Wei,Huiping Sui,Han Zhang et al.
Diyuan Wei et al.
Aim: To assess the clinical, radiographic and patient-reported outcomes (PROs) of 6-mm short implants supporting splinted crowns in posterior regions at 12 years following early prosthetic loading. ...
Systemic Antibiotics in the Surgical Treatment of Peri-Implantitis: Impact on the Salivary Microbiome [0.03%]
外科治疗 peri-implantitis 中系统性抗生素对唾液菌群的影响
Caroline Riben Grundström,Bodil Lund,Nagihan Bostanci et al.
Caroline Riben Grundström et al.
Aim: To exploratorily compare the shifts in the salivary microbiome composition after administration of two combined systemic antibiotic regimens used in the surgical treatment of peri-implantitis. ...
Nonsteroidal Anti-Inflammatory Drugs and the Risk of Periodontitis Among Adults With Osteoarthritis: A Target Trial Emulation [0.03%]
在成人骨关节炎患者中非甾体抗炎药与牙周炎发病风险的关系：目标试验模拟研究
Ignacio Leiva-Escobar,Aiswarya Puzhakkara Chennas,Zoheir Alayash et al.
Ignacio Leiva-Escobar et al.
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) may mitigate periodontal tissue breakdown through cyclooxygenase (COX) inhibition; however, their long-term effects on the risk of periodontitis remain unclear. ...
Salivary Microbiota From a Periodontitis Donor Is Associated With Altered IgA-Related Immune Features in Germ-Free Mice [0.03%]
来自牙周炎供者的唾液微生物群与无菌小鼠中改变的IgA相关的免疫特征相关
K Irie,T Azuma,R Minoshima et al.
K Irie et al.
Aim: The oral microbiota has been implicated in mucosal immune regulation; however, its causal impact on salivary gland-associated immune features remains incompletely understood. In this proof-of-concept study, germ-free...
Prognostic Assessment of Tooth Survival After Treatment of Endodontic-Periodontal Lesions: A Retrospective Study [0.03%]
根管治疗后牙槽病变的预后评估：回顾性研究
Fumihiko Kimura,Risako Mikami,Koji Mizutani et al.
Fumihiko Kimura et al.
Aim: This retrospective cohort study aimed to identify pretreatment prognostic factors for tooth survival in teeth with endodontic-periodontal lesions (EPLs). ...
The Dietary Inflammatory Index and Periodontal Inflammation in Community-Dwelling Older Adults in Japan: The Otassha Study [0.03%]
日本社区居住老年人的饮食炎性指数与牙周炎症的相关性：Otassha研究结果报告
Akihiro Yuguchi,Masanori Iwasaki,Maki Shirobe et al.
Akihiro Yuguchi et al.
Aim: To investigate the association between the dietary inflammatory index (DII) and periodontal inflammation (periodontal inflamed surface area [PISA]) in community-dwelling older adults in Japan. ...
Efficacy of Adjunctive Agents in the Management of Biofilm-Induced Gingivitis: A Systematic Review and Meta-Analysis [0.03%]
辅助药物在生物膜诱导型龈炎管理中的疗效：系统评价和-meta分析
Elena Figuero,Crystal Marruganti,Nagore Ambrosio et al.
Elena Figuero et al.
Aim: In systemically healthy humans with gingivitis, what is the efficacy of active agents compared to negative control/placebo when used adjunctively to mechanical biofilm control in terms of changes in gingivitis/bleedi...
From the Proteome to Therapeutics: A Multi-Database Approach to Drug Discovery in Periodontitis-An Exploratory Pilot Study [0.03%]
从蛋白组学到治疗：针对牙周炎的药物发现多数据库方法探索性研究
Taisir Bozo,Annette Murr,Birte Holtfreter et al.
Taisir Bozo et al.
Introduction: This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug-target database screening. ...
Spatiotemporally Responsive BEC Nanoplatform Targets Neutrophils to Reprogram Immune Crosstalk and Alleviate Periodontal Inflamm-Ageing in Periodontitis [0.03%]
时空响应性BEC纳米平台靶向中性粒细胞以重编程免疫交叉通讯并缓解牙周炎中的牙周炎症老化
Jiaxin Luo,Jingxia Chen,Sicong Ren et al.
Jiaxin Luo et al.
Aim: To investigate the underlying mechanism of immune cell crosstalk in periodontal inflammatory ageing and to explore potential pharmaceutical interventions for safely reversing this process. ...