Comparative miRNA Expression Profiling Reveals Candidates Involved in Prostate Cancer Radioresistance [0.03%]
比较性microRNA表达分析揭示参与前列腺癌放射抗性的候选物
Sercan Ergun,Sezgin Güneş,Neslihan Hekim et al.
Sercan Ergun et al.
Prostate cancer is the most common malignancy among men worldwide, and treatment response depends on tumor radiosensitivity. Micrornas (mirnas) are key regulators of cell proliferation, apoptosis, and dna damage response, and have been impl...
Immune Cell Infiltration in Primary and Recurrent Glioblastoma, IDH-Wild Type: Validation of an Immunohistochemistry-Based Scoring System for Research and Clinical Practice [0.03%]
IDH野生型胶质母细胞瘤（初发和复发）中免疫细胞浸润：用于研究及临床实践的免疫组化评分系统的验证
Leontien Verlinden,Alex Michotte,Wilfried Cools et al.
Leontien Verlinden et al.
Significant heterogeneity in the immune microenvironment of Glioblastoma, IDH-wildtype (GBM), has been reported, necessitating a standardized approach to evaluate immune infiltration in the context of emerging immunotherapies. To address th...
Inhibitory Effects of Sapindus mukorossi Gaertn. Extract on Biofilm Formation and Quorum Sensing in Pseudomonas aeruginosa: A Natural Alternative to Combat Bacterial Resistance [0.03%]
Sapindus mukorossi Gaertn. 提取物抑制铜绿假单胞菌生物膜形成和群体感应：对抗细菌耐药性的天然替代品
Shubham R Choudhury,Cheenuma Sharma,Sanjay K S Patel et al.
Shubham R Choudhury et al.
Developing natural alternatives to antibiotics is an essential aspect for countering bacterial pathogens. This study focused on the influence of plant-derived extracts on biofilm and quorum-sensing (QS) inhibition in Pseudomonas aeruginosa....
Human Coronavirus 229E May Infect Human Lung Vascular Endothelium and Induce Delayed Inflammatory and Antiviral Response [0.03%]
人冠状病毒229E可能感染人类肺血管内皮细胞并诱发炎症和抗病毒反应的延迟发生
Robert Szewczyk,Mateusz Gawrysiak,Jolanta Kalinowska et al.
Robert Szewczyk et al.
The effect of human coronaviruses (HCoVs) on airway epithelial cells is known and very well described. However, their influence on the human lung endothelium remains poorly understood. In this study, we assess the effect of low pathogenic H...
Sevoflurane Preconditioning Mitigates Hypoxia and Reoxygenation Injury in Cardiomyocytes Through microRNA-451a Regulation [0.03%]
通过微调miR-451a调节的异氟醚预处理可通过减轻心肌细胞缺氧和再氧化损伤来减轻心肌细胞损伤
Qiang Li,Xibao Shi,Jinping Li et al.
Qiang Li et al.
This study investigated whether Sevoflurane preconditioning (Sevo-pre) attenuates hypoxia/reoxygenation (H/R)-triggered myocardial damage by targeting microRNA-451a (miR-451a) and its downstream target interleukin 6 receptor (IL6R). Rat emb...
Insights of Bacterial Biofilm Suppression by Cucurbita moschata Seed-Mediated ZnO Nanorods [0.03%]
Cucurbita moschata种子介导的ZnO纳米棒抑制细菌生物被膜的机制研究
Suhasini Mallick,Biti Debnath,Rina Rani Ray
Suhasini Mallick
Biogenically synthesized ZnO nanorods using Cucurbita moschata seed have demonstrated significant antibiofilm activity against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Building on our previous findings, the current study e...
Detection of Mycobacterium tuberculosis in Ziehl-Neelsen Stained Sputum Smear Specimens Using Deep Learning Techniques [0.03%]
基于深度学习技术的ZN痰涂片结核分枝杆菌检测研究
Ozlem Genc,Serpil Genc,Cuneyt Ozdemir et al.
Ozlem Genc et al.
The initial step in diagnosing tuberculosis involves the microscopic examination of sputum samples using acid-fast staining to identify bacilli. However, this conventional method is labor-intensive, requires specialized expertise, is suscep...
Control of the Food-Borne Pathogen, Shigella flexneri 1457 by Using a Plant Polyphenol Naringenin [0.03%]
黄酮类化合物柚皮素控制食物源性病原菌志贺氏菌1457的研究
Vasudevan Ramya,Singaravel Mahalakshmi,Elumalai Rajalakshmi et al.
Vasudevan Ramya et al.
The most contagious forms of shigellosis and bacterial dysentery are caused by the gram-negative bacteria Shigella flexneri. Antibiotics like ciprofloxacin and synthetic antimicrobial agents are used to treat this infection; however, their ...
Low and High Pressor Doses of Ang II Lead to Two Distinct Phenotypes of Hypertensive Heart Disease in Mice [0.03%]
低、高血管紧张素II剂量引起的小鼠高血压性心脏病表型差异研究
Diana Törmä,Tuisku Suoranta,Mimmi Rinta-Harri et al.
Diana Törmä et al.
Hypertension is a major contributor to cardiovascular diseases, being the most common comorbidity and the biggest risk factor in heart failure with preserved ejection fraction. Angiotensin II (Ang II) is a known hypertension and heart failu...
Fusobacterium nucleatum Enhances Immune Escape in Colorectal Cancer by Inducing H3K18 Lactylation of CD274 (PD-L1) Protein Through Lactate Accumulation [0.03%]
核梭杆菌通过乳酸累积诱导CD274(PD-L1)蛋白H3K18乳酰化增强 colorectal cancer免疫逃逸
Chong Li,Jing Li,Lv Hu et al.
Chong Li et al.
Fusobacterium nucleatum (Fn), an intratumoral pathogenic bacterium, is confirmed to be associated with tumor progression in colorectal cancer (CRC). To evaluate CD8+ T cell function against CRC cells, their cytotoxicity was determined via l...