"Fertile" Mutations in SARS-CoV-2 RNA More Frequently Occurred in Hairpin Loops That Determine Virus Evolution [0.03%]
“肥沃”的突变在SARS-CoV-2 RNA中更常发生在发夹环结构中，该结构决定了病毒的进化方向
Philippe Colson,Pierre Pontarotti,Jacques Fantini et al.
Philippe Colson et al.
RNA hairpins may constitute a foundation of genetic evolution both in viruses and other organisms. Stem-loops theoretically comprise a stable part, the double-stranded stem, and a single-stranded loop allowing evolution. Here we tested for ...
Ekta Tyagi,Anjali Sachan,Rajabrata Bhuyan et al.
Ekta Tyagi et al.
Biofilms are microbial communities enclosed in an extracellular polymeric substance (EPS), significantly contributing to antimicrobial resistance (AMR) in medical, industrial, and environmental settings. Their matrix enhances microbial surv...
The TH1/TH2 Response Imbalance Zika Virus Pathogenesis: An Immunological Paradox [0.03%]
小胶质细胞极化在神经系统疾病中的作用：从生理到病理的转变
Carla Menezes,Lívia Martins,Gustavo Ferro et al.
Carla Menezes et al.
Since its identification in 1947 and its global emergence in the Americas decades later, the Zika virus (ZIKV) has proven to be a multifaceted challenge to public health. Among the many aspects that remain poorly understood, the complex imm...
Interaction Between Epithelial-Mesenchymal Transition and Tumor Microenvironment Biomarkers and Their Impact on the Prognosis of Oral Tongue Squamous Cell Carcinoma [0.03%]
上皮间质转化与肿瘤微环境标志物的相互作用及其对舌鳞癌预后的影响分析
Hannah Gil de Farias Morais,Débora Frota Colares,Julliany Taverny Sousa et al.
Hannah Gil de Farias Morais et al.
To investigate, through immunohistochemistry, the interaction between the epithelial-mesenchymal transition (EMT) status and the tumor microenvironment (TME) in oral tongue squamous cell carcinomas (OTSCCs). A total of 61 cases of OTSCC wer...
Ex Vivo Goat Corneal Model for Investigating Host Immune Responses and Antifungal Drug Testing in Fusarium Keratitis [0.03%]
角结膜真菌感染的动物模型及抗真菌药物筛选研究进展
Pinal Trivedi,Shrinkhla Singh,Sikhasmita Dowari et al.
Pinal Trivedi et al.
Fusarium Keratitis is a corneal infection that causes blindness if left untreated. Immune profiling of Fusarium-infected corneas may facilitate the development of an effective immunotherapy. The ex vivo caprine (goat) cornea model examines ...
Influence of Nutritional Conditions on Coexistence of Pseudomonas aeruginosa and Staphylococcus aureus in the Dual-Species Biofilm [0.03%]
营养条件对铜绿假单胞菌和金黄色葡萄球菌双物种生物被膜中共存的影响
Somashekhar Kumbara Megha,Yuvarajan Subramaniyan,Blessy M Baby et al.
Somashekhar Kumbara Megha et al.
Pseudomonas aeruginosa is a prominent uropathogen associated with biofilm-related urinary tract infections. It can coexist in a biofilm environment with other pathogens, including Staphylococcus aureus, and the availability of metabolites i...
Rhodethrin and Antibiotic Synergism to Combat Enterococcus faecalis and Inhibit Biosynthesis of Extracellular Polymeric Substances [0.03%]
Rhodethrin和抗生素的协同作用对抗肠球菌及抑制胞外多糖合成
Eswar Rao Tatta,Ranjith Kumavath
Eswar Rao Tatta
Biofilms are structured communities of microorganisms embedded in extracellular polymeric substances (EPSs) that adhere to surfaces or interfaces. These biofilms are resistant to antimicrobial agents and are responsible for persistent infec...
Identification of Evolutionary Trade-Offs Associated With High-Level Colistin Resistance in Acinetobacter baumannii [0.03%]
鲍曼不动杆菌高水平多粘菌素耐药的进化权衡鉴定
Kusumita Acharya,Upasana Bhattacharya,Shatarupa Biswas et al.
Kusumita Acharya et al.
Colistin (COL) belongs to the polymyxin group of drugs, which possesses a positive charge and interacts with lipopolysaccharide (LPS) of Gram-negative bacterial outer membranes. Acinetobacter baumannii, a bacterium in the "ESKAPE" group of ...
Beyond Frozen Section: Evolving Methodologies for Intraoperative Assessment of Surgical Margins in Breast Conservation Surgery [0.03%]
超越快速病理：乳腺癌保乳手术术中切缘评估的方法学进展
Ayesha Ahmed
Ayesha Ahmed
Intraoperative margin evaluation is very important in the management of breast cancer patients, specifically in breast conserving therapy in which attaining negative margins is a prerequisite. Microscopic involvement of margins shows two to...
MiR-490-3p/TGFBR1 Axis Prevents Atrial Fibrillation by Inhibiting Cellular Fibrosis [0.03%]
miR-490-3p/TGFBR1轴通过抑制细胞纤维化防治房颤
Xueshan Zhang,Zongliang Yu
Xueshan Zhang
Atrial fibrillation (AF) ranks among the most prevalent cardiovascular diseases, and its prevalence is increasing over the years. Atrial fibrosis is one of the key causes of AF. This study aimed to investigate miR-490-3p levels in AF and th...