Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials [0.03%]
与精神分裂症相关的认知障碍的药理和机制干预措施:注册临床试验综述
Bahareh Peyrovian,Lena Palaniyappan,Theodore T Kolivakis et al.
Bahareh Peyrovian et al.
Background: Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify ...
Giovanni A Fava,Jenny Guidi
Giovanni A Fava
Clinical judgment is currently perceived as an intuitive art that is going to be replaced by growing technology and artificial intelligence. Even though patients look for good clinical judgment when they seek medical attention and clinician...
Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study [0.03%]
性别和诊断对严重精神疾病临床变量和神经认知表现的影响:PsyCourse研究结果
Maria Serra-Navarro,Maria Heilbronner,Brisa Solé et al.
Maria Serra-Navarro et al.
Introduction: Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI....
Efficacy and Acceptability of Licensed and Off-Label Pharmacological Interventions for Insomnia in Patients With Severe Mental Illness: A Systematic Review and Meta-Analysis of Randomised Trials [0.03%]
系统性回顾与元分析:严重精神疾病患者的失眠症经批准的和非适应症药物干预的有效性和可接受度
Nina Friis Bak Fuglsang,Nanna Marker Madsen,Søren Lundorff Jacobsen et al.
Nina Friis Bak Fuglsang et al.
Background: A wide range of drugs is used to alleviate insomnia symptoms in individuals with severe mental illness (SMI), including licensed drugs and sedating drugs prescribed off-label. Yet, no review has gathered the e...
Predicting Cognitive Change During Treatment for Inpatient Depression: Secondary Analysis From a Randomized Controlled Trial [0.03%]
一项住院抑郁症治疗的随机对照试验的二次分析:预测治疗期间的认知变化
Zoe A Odering,Jennifer Jordan,Cameron J Lacey et al.
Zoe A Odering et al.
Introduction: Individuals hospitalized with depression are particularly impacted by cognitive impairment. Identifying variables that predict improvements in cognition across treatment may inform more targeted and effectiv...
Improving the Accuracy and Reliability of Ratings on the Hamilton Depression Rating Scale via a Video-Based Training Program [0.03%]
基于视频的培训项目改进汉密尔顿抑郁量表评分的精准性和可靠性
Pernille Kølbæk,Botilla Dalsgaard Jensen,Erik Roj Larsen et al.
Pernille Kølbæk et al.
Introduction: The clinician-rated 17-item Hamilton Depression Rating Scale (HAM-D17) allows for a systematic severity assessment of depressive symptoms. Applying the HAM-D17 in clinical practice requires that staff member...
Unravelling the Link Between Body Mass Index and Cognitive Performance in Individuals With Bipolar Disorder and Exploration of PRS Moderation Effect: Findings From the PsyCourse Study [0.03%]
探讨双向情感障碍患者体质指数与认知表现关联及PRS调制效应的 PsyCourse 研究结果
B Solé,L Montejo,M Budde et al.
B Solé et al.
Introduction: Bipolar disorder (BD) is a severe mental disorder characterized by extreme mood swings, often accompanied by metabolic comorbidities, such as cardiovascular disease, which increase mortality and reduce quali...
Internet-Based Cognitive Assessments During Remission in Bipolar Disorder: Subjective Cognitive Function and Clinical Severity [0.03%]
双相障碍缓解期的互联网认知评估:基于受试者的认知功能和临床严重程度
Kristin Svee,Gunnar Morken,Tor Ivar Hansen et al.
Kristin Svee et al.
Introduction: Cognitive impairment is well-established in bipolar disorder and significantly impacts daily functioning. However, the relationship between self-evaluated cognitive functions and objective cognitive tests is...
Olli Vaurio,Jari Tiihonen,Markku Lähteenvuo et al.
Olli Vaurio et al.
Introduction: Despite well-known diagnostic and neurobiological overlaps between psychopathic traits and schizophrenia, it has remained unclear whether psychopathic traits increase the risk for later schizophrenia. Former...
Risk of Dementia in Patients Suffering From Psychosis-A Danish Register-Based Cohort Study [0.03%]
丹麦登记处基于队列的精神病患者患痴呆症的风险研究
Simone Normark,Marie Kim Wium-Andersen,Merete Osler et al.
Simone Normark et al.
Objective: To investigate the association of psychosis with subsequent risk of dementia and to explore any impact of age at psychosis onset. Methods: ...