Effects of long-term use of depo-medroxyprogesterone acetate on lipid metabolism in Nepalese women [0.03%]
长期使用醋酸美庄孕酮对尼泊尔妇女脂质代谢的影响
Binod Kumar Yadav,Rajesh Kumar Gupta,Prajwal Gyawali et al.
Binod Kumar Yadav et al.
Various synthetic progestogens that are used as contraceptives have been reported to influence lipid and lipoprotein fractions differently. Depo-medroxyprogesterone acetate (DMPA), a synthetic progestogen, is used by Nepalese women as a con...
Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome [0.03%]
导致急性冠脉综合征患者氯吡格雷抵抗的临床、药代动力学及药物基因 组学决定因素分析
Kyoung-Jin Park,Hae-Sun Chung,Suk-Ran Kim et al.
Kyoung-Jin Park et al.
Background: Clopidogrel has been widely used to prevent recurrent ischemia in patients with acute coronary syndrome (ACS). However, inter-individual variability in response to clopidogrel has been a problem in the clinica...
A rare case of microgranular acute promyelocytic leukemia associated with ider(17)(q10)t(15;17) in an old-age patient [0.03%]
一例老年伴ider(17)(q10)t(15;17)微小颗粒变急性早幼粒细胞白血病患者罕见病例报告
Min Jin Kim,Sun Young Cho,Gayoung Lim et al.
Min Jin Kim et al.
We present a rare case of microgranular variant acute promyelocytic leukemia (APL) associated with ider(17)(q10)t(15;17)(q22;q12) of an old-age patient. The initial chromosome study showed a 46,XX,del(6)(?q21q25),der(15)t(15;17)(q22;q12),id...
Erythroleukemia relapsing as precursor B-cell lymphoblastic leukemia [0.03%]
红白血病转化为前体B细胞急性淋巴细胞白血病复发
Borae G Park,Chan-Jeoung Park,Seongsoo Jang et al.
Borae G Park et al.
AML relapsing as ALL has rarely been reported. We describe the case of a 62-yr-old man who was diagnosed with erythroleukemia with a complex karyotype and achieved complete hematologic and cytogenetic remission after induction chemotherapy....
Robert Hawkins
Robert Hawkins
Changes in renal function are one of the most common manifestations of severe illness. There is a clinical need to intervene early with proven treatments in patients with potentially deleterious changes in renal function. Unfortunately prog...
The path to clinical proteomics research: integration of proteomics, genomics, clinical laboratory and regulatory science [0.03%]
临床蛋白质组学研究之路：整合蛋白质组学、基因组学、临床检验与监管科学
Emily S Boja,Henry Rodriguez
Emily S Boja
Better biomarkers are urgently needed to cancer detection, diagnosis, and prognosis. While the genomics community is making significant advances in understanding the molecular basis of disease, proteomics will delineate the functional units...
Clinical, biochemical and genetic analyses in two Korean patients with medium-chain acyl-CoA dehydrogenase deficiency [0.03%]
两名患中链酰基辅酶a脱氢酶缺乏症的韩国患者的临床生化和基因分析结果
Hye In Woo,Hyung-Doo Park,Yong-Wha Lee et al.
Hye In Woo et al.
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive hereditary metabolic disorder of mitochondrial fatty acid β-oxidation. It is characterized by hypoketotic hypoglycemia, hyperammonemia, seizure, coma, and sud...
Miller-Dieker syndrome with der(17)t(12;17)(q24.33;p13.3)pat presenting with a potential risk of mis-identification as a de novo submicroscopic deletion of 17p13.3 [0.03%]
临床表现为17号染色体微缺失的12号染色体和17号染色体易位相关的米勒-迪克综合征患者
Young Jin Kim,Shin Yun Byun,Seon A Jo et al.
Young Jin Kim et al.
Miller-Dieker syndrome involves a severe type of lissencephaly, which is caused by defects in the lissencephaly gene (LIS1). We report the case of a female infant with der(17)t(12;17)(q24.33;p13.3)pat caused by an unbalanced segregation of ...
Bacteremia caused by Corynebacterium amycolatum with a novel mutation in gyrA gene that confers high-level quinolone resistance [0.03%]
由具有高水平喹诺酮类耐药新突变的麻氏棒状杆菌引起的菌血症
Seoyoung Yoon,Heejung Kim,Yangsoon Lee et al.
Seoyoung Yoon et al.
Although Corynebacterium amycolatum can cause opportunistic infections, it is commonly considered as contaminant. In this report, we present a case of bacteremia caused by C. amycolatum with a novel mutation in the gyrA gene that confers hi...
Sadia Shakoor,Mohammad Wasay,Afia Zafar et al.
Sadia Shakoor et al.
Plant root hairs are commonly found artifacts in parasitology specimens and may be confused with helminthes by an untrained eye. We report a case of brain tuberculoma where the tissue sample was contaminated with root hair derived from tap ...