Real-world safety and tolerability of rapid infusion obinutuzumab in chronic lymphocytic leukemia, small lymphocytic lymphoma and non-Hodgkin lymphoma: a provincial review [0.03%]
奥比妥珠单抗快速输注治疗慢性淋巴细胞白血病、小淋巴细胞淋巴瘤及非霍奇金淋巴瘤的现实世界安全性和耐受性：一例省级审查结果
Harshal Senthil,Scott Streilein,Theresa Whiteside et al.
Harshal Senthil et al.
Not available.
Interim analysis of a multicenter study on patient-guided dose reduction of tyrosine kinase inhibitors in chronic myeloid leukemia: the RODEO study [0.03%]
一项关于慢性粒细胞白血病患者指导的酪氨酸激酶抑制剂剂量减少的多中心研究的中期分析：RODEO研究
Dina Nienke Lokhorst,Yolba Smit,Bart J F Van den Bemt et al.
Dina Nienke Lokhorst et al.
Patient-guided dose reduction, as explored in the RODEO study, offers a promising approach to alleviate the burden of tyrosine kinase inhibitor (TKI) therapy in chronic myeloid leukemia (CML). Supported by shared decision-making (SDM) and a...
Real-world safety and efficacy of rADAMTS13 prophylaxis in congenital thrombotic thrombocytopenic purpura: experience from Polish patients previously treated with fresh frozen plasma [0.03%]
针对先天性血栓性血小板减少性紫癜的rADAMTS13预防治疗：波兰接受过新鲜冰冻血浆治疗患者的经验
Jerzy Windyga,Joanna Zdziarska,Magdalena Górska-Kosicka et al.
Jerzy Windyga et al.
Not available.
Madeline Franke,Alejandro Ferrer,Mrinal M Patnaik
Madeline Franke
Telomere biology disorders (TBDs) comprise a heterogenous group of inherited conditions characterized by impaired telomere maintenance, resulting in abnormal telomere lengths and/or telomere dysfunction. The clinical spectrum of TBDs is bro...
HES1 regulates bone marrow mesenchymal stromal cell function by suppressing NFATc2-mediated inflammation [0.03%]
HES1通过抑制NFATc2介导的炎症调节骨髓间充质干细胞功能
Anthony Z Zhu,Zhilin Ma,Emily V Wolff et al.
Anthony Z Zhu et al.
The Notch target gene, Hairy and enhancer of split-1 (HES1), encodes a basic helixloop- helix transcriptional repressor that influences cell proliferation and differentiation in embryogenesis. Our previous studies indicate that HES1 is requ...
Utility of the Central Nervous System International Prognostic Index in patients with primary mediastinal large B-cell lymphoma treated with rituximab-containing chemoimmunotherapy [0.03%]
利妥昔单抗联合化疗治疗原发性纵隔大B细胞淋巴瘤患者中枢神经系统国际预后指数的临床意义分析
Jiayu Yang,Anna R Hayden,Diego Villa et al.
Jiayu Yang et al.
Not available.
Intravenous immunoglobulins in the management of acute chest syndrome in two Jehovah's witnesses with sickle cell disease [0.03%]
输注静脉丙种免球蛋白治疗两名不愿接受血液输注的镰形细胞贫血病患者的急性胸部综合症疗效观察
Francesca Begali,Jacopo Ceolan,Silvia Vitale et al.
Francesca Begali et al.
Not available.
Long-term outcomes in FLT3-mutated acute myeloid leukemia after frontline hypomethylating agent, venetoclax and a FLT3 inhibitor [0.03%]
一线低甲基化药物、维奈克拉和FLT3抑制剂后FLT3突变急性髓系白血病的长期预后
Nicholas J Short,Sanam Loghavi,Musa Yilmaz et al.
Nicholas J Short et al.
Triplet regimens with a hypomethylating agent, venetoclax and a FLT3 inhibitor yield high rates of response in newly diagnosed FLT3-mutated AML. However, the long-term outcomes and patterns of relapse with these triplet regimens are not wel...
The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology [0.03%]
贝叶斯中期分析在血液肿瘤随机Ⅱ期和Ⅲ期临床试验中的增量价值研究
Anna J T Smit,Niek G Van der Maas,Bronno Van der Holt et al.
Anna J T Smit et al.
Not available.
NFATc1 and NFATc2 regulate glucocorticoid resistance in pediatric T-cell acute lymphoblastic leukemia through modulation of cholesterol biosynthesis and the WNT/β-catenin pathway [0.03%]
NFATc1和NFATc2通过调节胆固醇生物合成和WNT/β-连环蛋白途径来调控儿童T细胞急性淋巴细胞白血病对糖皮质激素的耐药性
Giulia Veltri,Alberto Peloso,Alice Cani et al.
Giulia Veltri et al.
The glucocorticoid (GC) resistance onset in pediatric T-cell Acute Lymphoblastic Leukemia (T-ALL) patients remains one of the biggest challenges in current cancer treatment. The mechanisms driving this resistance are still not fully underst...