Theoretical Calculations, Docking, and Experimental Evaluation of Nanotube Surface Antimicrobial Activity [0.03%]
理论计算、对接和实验评估纳米管表面抗菌活性
Vahdettin Aslan,Yasemin Keşkek Karabulut,Aybek Yiğit et al.
Vahdettin Aslan et al.
In this study, quantum chemistry computational methods were used to theoretically determine and experimentally verify the antibacterial activity of functionalized carbon nanotube (CNT) surfaces. CNTs with 2-2.5% -COOH ends were chemically t...
Cyclopentyl-linked N-Acylthioureas as Promising Urease Inhibitors: Insights from in vitro Bioassay, Structure-activity Relationships and Computational Analysis [0.03%]
通过体外生物测定，构效关系及计算分析获得有前景的脲酶抑制剂：环戊基连接N-酰基硫代尿素类化合物
Khansa Mumtaz,Sumera Zaib,Aamer Saeed et al.
Khansa Mumtaz et al.
Helicobacter pylori is a Gram-negative bacteria responsible for gastrointestinal disorders, including chronic gastritis and potentially life-threatening conditions like gastric cancer. To manage these adverse outcomes, inhibiting the urease...
Synthesis, X-ray Crystal Structures and Antibacterial Activity of Copper(II) Complexes Derived from Halo Substituted Hydrazones [0.03%]
含卤素取代肼
Zhonglu You,Niansui Song,Ziyi Qiao et al.
Zhonglu You et al.
Schiff bases bearing halo substituent groups have interesting biological activities. In this work, two new hydrazone type Schiff bases N'-(3,5-dibromo-2-hydroxybenzylidene)-3-methylbenzohydrazide (HL1) and N'-(4-chloro-2-hydroxybenzylidene)...
Synthesis, X-Ray Crystal Structures and Urease Inhibitory Activity of 3,5-Dihydroxy-N'-(pyridin-2-ylmethylene)benzohydrazide and its Copper(II) and Nickel(II) Complexes [0.03%]
3,5-二羟基-N'-（吡啶-2-亚甲基）苯胲酸及其铜(II)和镍(II)配合物的合成、X-射线晶体结构和尿素酶抑制活性研究
Zhonglu You,Ziyi Qiao,Yaoyao Cao et al.
Zhonglu You et al.
Hydrazone compounds have interesting biological activities. In this work, a new hydrazone compound 3,5-dihydroxy-N'-(pyridin-2-ylmethylene)benzohydrazide (HL) was synthesized and characterized by IR, UV-Vis, 1H and 13C NMR spectroscopy. The...
Synthesis, Crystal Structures and Urease Inhibition of Three Copper(I) Complexes Derived from 2-(2,4-Dichlorobenzydene)hydrazine-1-carbothioamide [0.03%]
由2-(2,4-二氯苯扎啶基)碳硫酰胺肼合成三种铜配合物及其晶体结构和尿素酶抑制作用研究
Wen-Bo Yan,Bo Qiu,Jie Ren et al.
Wen-Bo Yan et al.
Reaction of 2-(2,4-dichlorobenzydene)hydrazine-1-carbothioamide (L), triphenylphosphine with cuprous chloride, cuprous bromide and cuprous iodide, respectively, under the nitrogen atmosphere, afforded three new copper(I) complexes [CuClL(Ph...
Fostering Chemical Literacy through a Non-Formal Forensic Chemistry Module for 13-Year-Old Students [0.03%]
通过非正规法医化学模块培养13岁学生的化学素养
Alenka Dražić,Iztok Devetak
Alenka Dražić
Traditional chemistry education often struggles to engage students due to abstract content and limited contextual relevance. This study explores the impact of a non-formal forensic chemistry module (NFFCM) designed to foster chemical litera...
Camel Bones as a Source of Fat: Optimization of Extraction Methods and Fatty Acid Composition Analysis [0.03%]
骆驼骨作为脂肪来源：提取方法的优化及脂肪酸组成分析
Mohamed Mokadem,Habib Farhat,Khadra Mokadem
Mohamed Mokadem
This study explores the viability of using camel bones, an abundant by-product in North Africa and the Middle East, as a novel source of fat for biodiesel production. A moist-heat extraction process using a pressure cooker was employed to e...
Camellia Yokdonensis Leaves: Antioxidant, Potential Antidiabetic and In Vitro Anti-inflammatory Activities [0.03%]
山茶油DON叶的抗氧化、潜在抗糖尿病和体外抗炎活性研究
Trang Thi Nguyen,Pham M Tuan,Danh C Vu
Trang Thi Nguyen
This study investigated the phenolic content, antioxidant activity, α-amylase and α-glucosidase inhibitory effects, and albumin denaturation inhibitory activity of extracts from the leaves of Camellia yokdonensis, a plant species native t...
Quercetin-3 Sulfate: A Novel Inhibitor Targeting Helicobacter Pylori Revealed through Molecular Docking and Dynamic Simulations [0.03%]
山柰酚-3-硫酸酯：通过分子对接和动态模拟发现的一种新型抗幽门螺旋杆菌抑制剂
Mohammed Baqur Al-Shuhaib,Hayder O Hashim,Mudher K Mohammed et al.
Mohammed Baqur Al-Shuhaib et al.
Type II dehydroquinase (DHQase) is a pivotal enzyme in the synthesis of aromatic amino acids essential for Helicobacter pylori's survival. It possesses distinctive characteristics and exhibits limited sequence or structural similarity to ot...
Interpreting the Conformational Dynamics Over Interaction of FAM222A Protein with Amyloid-Beta Peptides [0.03%]
FAM222A蛋白与淀粉样β肽相互作用的构象动力学解读
Nail Besli,Nilufer Ercin,Miguel Carmena-Bargueño et al.
Nail Besli et al.
Alzheimer's disease (AD), a neurological disorder with increasing prevalence worldwide, presents a significant challenge to the medical community. The molecular mechanism underpinning its neuropathology is still wholly unexplained. Recent i...