40 years of CENP-A: the foundation of a new era of centromere biology [0.03%]
CENP-A发现40年：新的中心粒生物学时代的基石
Simona Giunta,Tatsuo Fukagawa,Rachel J O&#x;Neill et al.
Simona Giunta et al.
The role of chromosome/kinetochore-driven microtubule generation in Drosophila spindle assembly [0.03%]
染色体/着丝点驱动的微管生成在果蝇纺锤体装配中的作用
Maurizio Gatti
Maurizio Gatti
In animal cells, proper spindle assembly requires generation of large numbers of microtubules (MTs) through three main pathways: MT nucleation by the centrosomes, nucleation near chromosomes/kinetochores and augmin-mediated nucleation from ...
Najoua Zeffate,Mohammed El Amine Bechar,Jean-Marie Guyader et al.
Najoua Zeffate et al.
The segmentation of overlapping chromosomes in metaphase images is a longstanding challenge in cytogenetics, where limited spectral contrast in conventional RGB imaging. In this study, we explore hyperspectral imaging (HSI) as a promising a...
Rapid assembly of functional modules for generating human artificial chromosome constructs compatible with epigenetic centromere seeding [0.03%]
用于表观遗传着丝粒种子的人工染色体结构快速装配功能模块构建
Gabriel J Birchak,Daniel G Gibson,Praveen Kumar Allu et al.
Gabriel J Birchak et al.
The ongoing development of human artificial chromosomes (HACs) will permit investigation into essential centromere processes and the means to deliver large genetic cargoes to target cells. Starting with large (~750 kb) yeast artificial chro...
Development of wheat D genome-specific molecular markers based on subgenome-specific repeats [0.03%]
基于亚基因组特异性重复序列的小麦D基因组特异分子标记的开发
Tatiana V Danilova,Ahmed Charif,Katherine Frels et al.
Tatiana V Danilova et al.
Species from the tribe Triticeae can be used for wheat improvement by introgression of valuable genes through wide hybridization. More than 85% of Triticeae genomes consist of repetitive sequences with species-specific content and compositi...
Sustainable integrative cell biology: CENP-C is guilty by association [0.03%]
可持续的整合细胞生物学：CENP-C因关系而有罪
Natalia Y Kochanova,Itaru Samejima,William C Earnshaw
Natalia Y Kochanova
In the 40 years since the discovery of the CENP proteins, many studies have examined the role of these proteins and their interactions with other chromosomal proteins of the centromere and beyond. Together, these studies have yielded vast a...
Identification of cDNA-AFLP fragments associated with the B chromosome from different developmental stages of maize anthers [0.03%]
不同小花发育时期玉米雄蕊中与B染色体相关的cDNA-AFLP片段的鉴定
Cheng-Hong Li,Pei-Hsuan Wu,Ya-Ming Cheng
Cheng-Hong Li
B chromosomes are nonessential chromosomes and are considered genetically inert. However, the maize B chromosome possesses several genetic properties during male gamete development in anthers. To determine whether the transcriptome of maize...
From minor loci to major players? Satellite DNA diversification in Crepis sensu stricto [0.03%]
从次要位点到主要参与者？宽翼播娘蒿卫星DNA的分化
Magdalena Senderowicz,Natalia Borowska-Żuchowska,Gülru Yücel et al.
Magdalena Senderowicz et al.
Crepis sensu lato (s.l.) comprises species with remarkable variation in genome size, chromosome number, and karyotype structure, making this genus a valuable model for studying genome and chromosome evolution. Studies in various plant syste...
Co-morbid monogenic disorders at chromosome region 1q2: LMNA- and FLG-related disorders in a patient referred for assessment of joint hypermobility [0.03%]
染色体1q2区域的共病单基因异常：一名因关节过度活动征就诊患者中的LMNA和FLG相关障碍
Mayowa A Osundiji,Adedamola O Bello,Jennifer L Hand
Mayowa A Osundiji
The phenotypic similarities and genetic heterogeneity occurring in diverse forms of Ehlers Danlos Syndrome (EDS) subtypes and many heritable connective tissue disorders can pose a diagnostic challenge. In the wake of the growing application...
Samuel Corless,Gokilavani Thangavel,Sylvia Erhardt
Samuel Corless
Centromeres have been the focus of extensive research for almost a century, so it may come as a surprise that a consistent definition and nomenclature for these structures remains elusive. In recent times, centromeric chromatin is most freq...