The role of satellite DNA-enriched heterochromatic variants in reproductive disorders: Insights from standardized cytogenetic analysis [0.03%]
富含卫星DNA的异染色质变异体在生殖障碍中的作用：来自标准化细胞遗传学分析的新见解
Sílvia Pires,Isaltina França,Pedro Oliveira et al.
Sílvia Pires et al.
Non-coding DNA, long considered "junk", is now recognized as a central regulator of genome architecture. Highly repetitive satellite DNA sequences shape heterochromatin and are essential for chromosome stability, segregation, and gene regul...
Cytogenomics of Myloplus tiete reveals conserved satellite DNAs since the Late Eocene in Serrasalmidae (Teleostei, Characiformes) [0.03%]
晚始新世以来真骨鱼目脂鲤科鱼类染色体水平基因组学中的保守卫星DNA
Francisco de Menezes Cavalcante Sassi,Giovanna Igepi,Beatriz Lopes Torgan et al.
Francisco de Menezes Cavalcante Sassi et al.
The Neotropical family Serrasalmidae (pacus and piranhas) exhibits remarkable karyotype conservation, yet cytogenetic data remain limited for several genera, particularly Myloplus. Here we present the first integrative cytogenomic character...
Stable resynthesized Brassica napus lines show similar meiotic behaviour to established B. napus [0.03%]
稳定的重构油菜雷帕霉素靶蛋白自交系与传统油菜单倍体的行为表现相似
Vinita Ramtekey,Elizabeth Ihien Katche,Mariana Baez et al.
Vinita Ramtekey et al.
Brassica napus (rapeseed/canola) is an allotetraploid (AACC, 2n = 4x = 38) resulting from spontaneous hybridization between B. rapa (AA, 2n = 2x = 20) and B. oleracea (CC, 2n = 2x = 18). Although established B. napus is meiotically stable, ...
Characterization of neocentromeric marker chromosome derived from chromosome 11: a rare entity in four patients with acute leukemia [0.03%]
11号染色体衍生的近端着丝粒标记染色体的特征在四个急性白血病患者中的罕见实体现象
Iveta Mendlikova,Jana Brezinova,Karla Svobodova et al.
Iveta Mendlikova et al.
Neocentromeres are newly formed chromosomal regions that can replace the function of traditional centromeres and are well documented in human clinical studies. However, their occurrence in neoplasia, including acute leukemia, appears to be ...
Mixed modes of satellite DNA and transposable element evolution, which shape the repetitive landscape of air-breathing catfishes (Clarias) [0.03%]
卫星DNA和转座元件的混合演化模式塑造呼吸空气的塘虱鱼重复序列景观
Artem Lisachov,Thitipong Panthum,Worapong Singchat et al.
Artem Lisachov et al.
Repetitive DNA is a major organization component of eukaryotic genomes; however, its evolutionary dynamics in teleosts remain insufficiently understood. Catfish of the family Clariidae provide a valuable model for studying the evolutionary ...
Decoding Cdk1 control: from mitotic thresholds to meiotic specificity [0.03%]
解读Cdk1调控：从有丝分裂阈值到减数分裂特异性
Sandra A Touati
Sandra A Touati
The eukaryotic cell cycle is one of the most fundamental biological processes, ensuring the accurate duplication and segregation of the genome during mitosis. Decades of research across model systems have shown that this process is orchestr...
The DNA mismatch repair protein Msh4 is essential for meiosis of male but not for female in zebrafish [0.03%]
DNA错配修复蛋白Msh4在斑马鱼雄性但非雌性生殖细胞减数分裂过程中发挥重要作用
Yankun Guo,Yunbang Zhang,Yihui Mei et al.
Yankun Guo et al.
Meiotic recombination plays a crucial role in the correct separation of homologous chromosomes. The DNA mismatch repair protein Msh4 is a meiosis specific protein and msh4 defects were reported to associate with azoospermia and ovarian dysf...
Divergence and conservation of satellite DNA in the loggerhead sea turtle (Caretta caretta): a comparative cytogenomic analysis [0.03%]
中国海龟的着丝粒DNA和卫星DNA的比较细胞遗传分析：以舟山海域的海龟（Caretta caretta）为例研究其分化和保守性
Katerina V Tishakova,Anastasia A Proskuryakova,Dmitry Yu Prokopov et al.
Katerina V Tishakova et al.
Repetitive DNA sequences, particularly satellite DNA (satDNA), are key components of eukaryotic genomes with important structural and potential functional roles. In this study, we used long-read assemblies and short-read sequencing to perfo...
Emergence of satellite DNAs suggests centromeric repositioning as a driver of karyotypic variation of the freshwater darter characines (Apareiodon affinis) [0.03%]
卫星DNA的出现表明中心粒重新定位是淡水鲤鱼(Apareiodon affinis)核型变异的驱动因素
Marina Soares Ribas,Matheus Azambuja,Viviane Nogaroto et al.
Marina Soares Ribas et al.
Repetitive DNA sequences actively contribute to karyotype diversification by accumulating mutations, exhibiting susceptibility to DNA double-strand breaks that promote chromosomal rearrangements, and reshuffling within centromeric heterochr...
Visualizing DNA repair factor recruitment at sites of transcription in single cells [0.03%]
单细胞中转录位点的DNA修复因子募集的可视化技术
Tianyi Guan,Yuepeng Shi,Tae-Hee Lee et al.
Tianyi Guan et al.
Transcription-associated torsional stress presents a continuous threat to genome integrity that needs to be tightly controlled. Here we present a method for the visualization of genome maintenance events at sites of active transcription, wh...