Achiasmatic meiosis in the unisexual Amazon molly, Poecilia formosa [0.03%]
单性亚马逊 Molly 鱼 Poecilia formosa 的无交换减数分裂
Dmitrij Dedukh,Irene da Cruz,Susanne Kneitz et al.
Dmitrij Dedukh et al.
Unisexual reproduction, which generates clonal offspring, is an alternative strategy to sexual breeding and occurs even in vertebrates. A wide range of non-sexual reproductive modes have been described, and one of the least understood quest...
Ellman's reagent prevents dephosphorylation of histones during isolation of mitotic chromosomes [0.03%]
埃利曼试剂可防止在有丝分裂染色体分离过程中组蛋白去磷酸化
James R Paulson,Erica R Vander Mause,Elizabeth Dillinger et al.
James R Paulson et al.
Histones H1 and H3 are highly phosphorylated in mitotic HeLa cells but are rapidly dephosphorylated by endogenous protein phosphatases during the isolation of metaphase chromosomes. We show that this dephosphorylation can be prevented by in...
Sex chromosome differentiation via changes in the Y chromosome repeat landscape in African annual killifishes Nothobranchius furzeri and N. kadleci [0.03%]
非洲年度丽鱼科鱼类诺托布拉奇鱼（Furzeri组）性染色体分化通过Y染色体重复序列景观的变化实现
Jana Štundlová,Monika Hospodářská,Karolína Lukšíková et al.
Jana Štundlová et al.
Homomorphic sex chromosomes and their turnover are common in teleosts. We investigated the evolution of nascent sex chromosomes in several populations of two sister species of African annual killifishes, Nothobranchius furzeri and N. kadlec...
Constitutive heterochromatin propagation contributes to the X chromosome inactivation [0.03%]
构成性异染色质的传播对X染色体失活有贡献
Alexander I Shevchenko,Nikita A Rifel,Suren M Zakian et al.
Alexander I Shevchenko et al.
Imprinted X chromosome inactivation (iXCI) balances the expression of X-linked genes in preimplantation embryos and extraembryonic tissues in rodents. Long noncoding Xist RNA drives iXCI, silencing genes and recruiting Xist-dependent chroma...
Jovan Komluski,Eva H Stukenbrock,Michael Habig
Jovan Komluski
Non-Mendelian transmission has been reported for various genetic elements, ranging from small transposons to entire chromosomes. One prime example of such a transmission pattern are B chromosomes in plants and animals. Accessory chromosomes...
Stacey L Hanlon,Amanda M Larracuente
Stacey L Hanlon
Meiotic drive in house mice: mechanisms, consequences, and insights for human biology [0.03%]
小家鼠减数分裂驱动：机制、影响及对人类生物学的启示
Uma P Arora,Beth L Dumont
Uma P Arora
Meiotic drive occurs when one allele at a heterozygous site cheats its way into a disproportionate share of functional gametes, violating Mendel's law of equal segregation. This genetic conflict typically imposes a fitness cost to individua...
Non-random chromosome segregation and chromosome eliminations in the fly Bradysia (Sciara) [0.03%]
蝇(Bradysia(Sciara))的非随机染色体分离和染色体消除现象
Susan A Gerbi
Susan A Gerbi
Mendelian inheritance is based upon random segregation of homologous chromosomes during meiosis and perfect duplication and division of chromosomes in mitosis so that the entire genomic content is passed down to the daughter cells. The unus...
Rye B chromosomes differently influence the expression of A chromosome-encoded genes depending on the host species [0.03%]
异染色质型小麦B染色体对宿主基因表达的影响具有物种特异性
Anastassia Boudichevskaia,Anne Fiebig,Katrin Kumke et al.
Anastassia Boudichevskaia et al.
The B chromosome (B) is a dispensable component of the genome in many species. To evaluate the impact of Bs on the transcriptome of the standard A chromosomes (A), comparative RNA-seq analyses of rye and wheat anthers with and without addit...
Optimized Repli-seq: improved DNA replication timing analysis by next-generation sequencing [0.03%]
优化的重亚硫酸氢盐测序法：通过下一代测序改进DNA复制时间分析
Juan Carlos Rivera-Mulia,Claudia Trevilla-Garcia,Santiago Martinez-Cifuentes
Juan Carlos Rivera-Mulia
The human genome is divided into functional units that replicate at specific times during S-phase. This temporal program is known as replication timing (RT) and is coordinated with the spatial organization of the genome and transcriptional ...