Fold-back mechanism originating inv-dup-del rearrangements in chromosomes 13 and 15 [0.03%]
染色体13和15上发生inv dup del重排的折回机制
Bruna Burssed,Malú Zamariolli,Bianca Pereira Favilla et al.
Bruna Burssed et al.
Intrachromosomal rearrangements involve a single chromosome and can be formed by several proposed mechanisms. We reported two patients with intrachromosomal duplications and deletions, whose rearrangements and breakpoints were characterized...
Widespread chromosomal rearrangements preceded genetic divergence in a monitor lizard, Varanus acanthurus (Varanidae) [0.03%]
变色龙蜥蜴Varanus acanthurus遗传分化前染色体易位广泛发生
Jason Dobry,Erik Wapstra,Emily J Stringer et al.
Jason Dobry et al.
Chromosomal rearrangements are often associated with local adaptation and speciation because they suppress recombination, and as a result, rearrangements have been implicated in disrupting gene flow. Although there is strong evidence to sug...
Mamilla Soujanya,Ashish Bihani,Nikhil Hajirnis et al.
Mamilla Soujanya et al.
The nucleus is a complex organelle that hosts the genome and is essential for vital processes like DNA replication, DNA repair, transcription, and splicing. The genome is non-randomly organized in the three-dimensional space of the nucleus....
CRISPR/Cas9 and FLP-FRT mediated regulatory dissection of the BX-C of Drosophila melanogaster [0.03%]
利用CRISPR/Cas9和FLP/FRT系统对果蝇(Drosophila melanogaster)BX-C的调控元件进行解剖分析
Nikhil Hajirnis,Shubhanshu Pandey,Rakesh K Mishra
Nikhil Hajirnis
The homeotic genes or Hox define the anterior-posterior (AP) body axis formation in bilaterians and are often present on the chromosome in an order collinear to their function across the AP axis. However, there are many cases wherein the Ho...
Allison M Jevitt,Brooke D Rankin,Jingrong Chen et al.
Allison M Jevitt et al.
Cohesion between sister chromatids by the cohesin protein complex ensures accurate chromosome segregation and enables recombinational DNA repair. Sister chromatid cohesion is promoted by acetylation of the SMC3 subunit of cohesin by the ESC...
Evolution of satDNAs on holocentric chromosomes: insights from hemipteran insects of the genus Mahanarva [0.03%]
端部着丝点染色体上顺式作用元件的进化：来自渐变态昆虫属Mahanarva的新视野
Allison Anjos,Diogo Milani,Vanessa B Bardella et al.
Allison Anjos et al.
Satellite DNAs (satDNAs) constitute one of the main components of eukaryote genomes and are involved in chromosomal organization and diversification. Although largely studied, little information was gathered about their evolution on holocen...
X-chromosome inactivation patterns depend on age and tissue but not conception method in humans [0.03%]
人的x染色体失活模式取决于年龄和组织类型但与受孕方式无关
Patrycja Juchniewicz,Anna Kloska,Karolina Portalska et al.
Patrycja Juchniewicz et al.
Female somatic X-chromosome inactivation (XCI) balances the X-linked transcriptional dosages between the sexes, randomly silencing the maternal or paternal X chromosome in each cell of 46,XX females. Skewed XCI toward one parental X has bee...
Molecular characterization of eliminated chromosomes in Hessian fly (Mayetiola destructor (Say)) [0.03%]
麦红吸浆虫(Mayetiola destructor(Say))丢失染色体的分子特征分析
Yan M Crane,Charles F Crane,Sue E Cambron et al.
Yan M Crane et al.
Like other cecidomyiid Diptera, Hessian fly has stable S chromosomes and dispensable E chromosomes that are retained only in the germ line. Amplified fragment length polymorphisms (AFLP), suppressive subtractive hybridization (SSH), fluores...
High-density linkage maps and chromosome level genome assemblies unveil direction and frequency of extensive structural rearrangements in wood white butterflies (Leptidea spp.) [0.03%]
高密度连锁图谱和染色体水平基因组组装揭示了林白蝶(Lepideaspp.)广泛的结构重排的方向和频率
L Höök,K Näsvall,R Vila et al.
L Höök et al.
Karyotypes are generally conserved between closely related species and large chromosome rearrangements typically have negative fitness consequences in heterozygotes, potentially driving speciation. In the order Lepidoptera, most investigate...
Paternal UPD14 with sSMC derived from chromosome 14 in Kagami-Ogata syndrome [0.03%]
Kagami-Ogata综合征中存在 paternal UPD14 和源自14号染色体的sSMC
Jiyong Wang,Angie Lichty,Jill Johnson et al.
Jiyong Wang et al.