MMP-9 Gene Ablation Preserves Ejection Fraction During "Single-Hit" Model of HFrEF [0.03%]
MMP-9基因消融可保护"HFrEF单打击"模型中射血分数不下降
Oluwaseun E Akinterinwa,Mahavir Singh,Yuting Zheng et al.
Oluwaseun E Akinterinwa et al.
Heart failure is a leading cause of hospitalization worldwide, and evaluating the severity of heart failure often relies on the ejection fraction. Matrix metalloproteinases (MMPs) are crucial for tissue remodeling, and their dysregulation i...
Complete Mitochondrial Genome of Turrum coeruleopinnatum Provides Phylogenetic Context and Candidate Selection Signals Within Carangidae [0.03%]
Turrum coeruleopinnatum完整线粒体基因组的提供分类学背景和候选选择信号以卡拉氏科为例
Yang Chen,Xuehui Diao,Yixuan Lin et al.
Yang Chen et al.
The complete mitochondrial genome of Turrum coeruleopinnatum was sequenced and characterized to expand mitogenomic resources for Carangidae and to evaluate its phylogenetic placement and candidate selection signals. The circular mitogenome ...
Complete Mitochondrial Genome Analysis of Atypopenaeus stenodactylus and Its Phylogenetic Significance Within Penaeidae [0.03%]
Atypopenaeus stenodactylus虾线粒体基因组及其在虎虾属中的系统发育意义
Haoxue Wang,Jiaying Zeng,Pengfei Li et al.
Haoxue Wang et al.
Phylogenetic relationships within Penaeoidea, particularly among taxa of Penaeidae, have long remained controversial. To expand mitogenomic resources for Penaeidae and evaluate the phylogenetic position of Atypopenaeus stenodactylus (Stimps...
DSSMST: A Deterministic State Space Model for Self-Supervised Spatial Domain Identification in Spatial Transcriptomics [0.03%]
基于空间转录组学的空间领域自监督识别的确定性状态空间模型
Jirui Zhang,Xingyu Liu,Maoyuan Zhou et al.
Jirui Zhang et al.
Spatial transcriptomics (ST) has redefined our exploration of tissue-level cellular heterogeneity and spatial architecture; yet accurately pinpointing functional regions within complex, high-dimensional datasets remains a pressing hurdle. T...
Genetic Pattern and Diversity of Barbatia virescens: A RAD-Seq Analysis of Five Geographically Distributed Populations [0.03%]
五个人群的巴巴西亚病毒青株基因组模式及多样性分析：基于RAD测序技术的研究
Senping Jiang,Jiale Ma,Jiji Li et al.
Senping Jiang et al.
Barbatia virescens is an important economic bivalve along the Chinese coast, but its natural resources have been severely impacted by habitat degradation and overfishing. In this study, we applied RAD-seq to five wild populations and genera...
Retraction Note: IGF2 is Deregulated During the Development of Uterine Cervical Carcinoma in Indian Patients [0.03%]
撤回 notice:IGF2 在印度患者子宫颈癌发病期间的调节失调
Anirban Roychowdhury,Sudip Samadder,Dipanjana Indra Mazumder et al.
Anirban Roychowdhury et al.
Shilajit as a Natural Product from Sedimentary Rocks: Biological Origin and Antioxidant Properties [0.03%]
喜拉吉特：一种来自沉积岩的天然产物：生物起源和抗氧化性能
Asiye Ulug,Kezban Yildiz Dalginli,Funda Ozdemir Degirmenci et al.
Asiye Ulug et al.
Shilajit, a natural product with a documented history of use in traditional medicine for millennia, poses considerable challenges in elucidating its biological origin and pharmacological properties. In this study, a multidisciplinary approa...
The m6A Reader IGF2BP2 Suppresses Ferroptosis in Nasopharyngeal Carcinoma by Stabilizing NRF2 mRNA [0.03%]
IGF2BP2通过稳定NRF2信使RNA抑制鼻咽癌铁死亡
Xiaoyan Xu
Xiaoyan Xu
Nuclear factor erythroid 2-related factor 2 (NRF2) is a central transcriptional regulator of the antioxidant response and a key inhibitor of ferroptosis, and its overexpression is frequently observed in various cancers. However, the mechani...
Revisiting Algorithms, Tools, and Applications for Sequence and Phylogenetic Analyses in the NGS-Based Omics Era [0.03%]
下一代测序时代序列和系统发育分析的算法、工具及应用研究综述
Abhishek Kumar,Tikam Chand Dakal,Kayenat Parveen et al.
Abhishek Kumar et al.
Integrating high-throughput sequencing with phylogenetic analysis now spans everything from single genes to long-read pangenomes and metagenomes, yet practitioners still face fragmented, tool-centric guidance. This review revisits algorithm...
CircGABRB2_006 Drives Malignant Progression and EMT in Papillary Thyroid Carcinoma via the miR-296-5p/FGFR1 Axis [0.03%]
环状RNA CircGABRB2_006通过miR-296-5p/FGFR1轴驱动乳头状甲状腺癌恶性进展和上皮间质转化
Chuan Wan,Yanjun Guo,Han Guo et al.
Chuan Wan et al.
Circular RNAs (circRNAs) have emerged as important regulators of tumor progression; however, their roles in papillary thyroid carcinoma (PTC) remain incompletely understood. In this study, we investigated the expression, biological function...