Degradable biophotonic scaffolds of mesoporous graphene for regenerating neural pathways [0.03%]
用于再生神经通路的可降解生物光子支架中的介孔石墨烯
Omid Akhavan,Asadollah Kalantarian,Parvaneh Naserzadeh et al.
Omid Akhavan et al.
Mesoporous graphene frameworks (MGFs) were synthesized as p-type semiconductors with a nonzero band gap of ~1 eV and used as 3D photo-sensitive scaffolds for effective differentiation of human neural stem cells (hNSCs) into 3D-neural networ...
Bioinspired polymer-incorporated copper/iron nanozyme to boost cascade ROS accumulation for augmented hepatocellular carcinoma cuproptosis/ferroptosis [0.03%]
仿生聚合物包载铜铁纳米酶促进ROS级联积累诱导肝癌细胞铜依赖性细胞死亡/铁死亡增强型疗法
Sheng Zhang,Xiaomei Liu,Longxin Fan et al.
Sheng Zhang et al.
Hepatocellular carcinoma (HCC), an infamously incurable tumor, is extremely sensitive to ferroptosis, and its development is greatly aided by the glutathione (GSH) antioxidant defense system. We present a gelatin (GT)/hyaluronic acid (HA)-s...
Hydrogels and cryogels as in vitro engineered 3D neurodegenerative models: scope and significance [0.03%]
水凝胶和冰凝胶作为体外工程三维神经退行性疾病模型的作用和意义：范围与重要性
Ishaan Shah,Anuradha Vaidya,Yvonne Reinwald et al.
Ishaan Shah et al.
Neurodegenerative diseases (NDs) represent a diverse set of incurable and debilitating conditions that have become increasingly prevalent in recent years. A thorough understanding of the causes and mechanisms underlying these diseases is ne...
Enhancing the osteogenic potential of 3D-printed polycaprolactone/hydroxyapatite composite scaffolds via in-situ ZIF-8 surface modification [0.03%]
通过原位ZIF-8表面改性增强3D打印聚己内酯/羟基磷灰石复合支架的成骨潜能
Saba Moslemi,Ghasem Dini,Fatemeh Ejeian et al.
Saba Moslemi et al.
Bone defects remain a major clinical challenge, necessitating advanced scaffolds that combine suitable mechanics, bioactivity, and osteoinductive cues for effective regeneration. This study developed 3D-printed polycaprolactone/hydroxyapati...
Arginine-loaded silica nanoparticles inhibit E. faecalis in root canals [0.03%]
负载鸟氨酸的二氧化硅纳米颗粒可抑制根管内的粪肠球菌
Meng-Ya Li,Wen Zhang,Yi-Yuan Xia et al.
Meng-Ya Li et al.
Bacterial infection of the root canal system, especially by Enterococcus faecalis (E. faecalis), is the primary cause of root canal treatment failure, and intracanal medication has been proven to be an effective method for controlling root ...
Photosensitive and extracellular matrix-mimicking hydrogels promote the tendon-bone healing in rotator cuff injury [0.03%]
光敏感和细胞外基质模拟水凝胶促进肩袖损伤的肌腱骨愈合
Yuxuan Liu,Huanv Mao,Ziyang Tian et al.
Yuxuan Liu et al.
The healing of the tendon-bone interface remains a significant challenge due to the lack of suitable bioactive materials for promoting interface regeneration. To address this, we developed a photosensitive hydrogel system designed to mimic ...
Ag-enhanced β titanium alloys for surgical implants: microstructural regulation achieves superior strength, corrosion resistance and biocompatibility [0.03%]
用于外科植入物的 Ag 改性的 β 型钛合金：微观结构调控获得优异的强度、耐蚀性和生物相容性
Xiqun Ma,Yufei Tang,Sen Yu et al.
Xiqun Ma et al.
β-titanium alloys attract great interest in surgical implants due to its low elastic modulus. The addition of Ag further enhances the strength, ductility, corrosion resistance and biocompatibility of such alloys, which optimizes their comp...
Biomimetic bone scaffold functionalized with traditional Chinese medicine ingredients and collagen-binding IGF-1 for bone regeneration [0.03%]
一种用于骨再生的仿生骨支架，可固定中药成分和结合胶原蛋白的IGF-1
Xiaobo Gao,Bocheng Lei,Xiaomin Zhao et al.
Xiaobo Gao et al.
Many active ingredients from traditional Chinese medicine (TCM) have been applied in bone tissue engineering. However, the fuzzy mechanism of these ingredients limits their application. In this study, a novel biomimetic bone scaffold functi...
Electrospun CHIR99021-loaded cellulose acetate scaffolds stimulate osteogenic differentiation and mineralization in vitro [0.03%]
电纺负载CHIR99021的乙酸纤维素支架通过体外实验刺激成骨分化和矿化作用
Samir A Bello,Aimeé Rodríguez-Monroig,Andrea Vargas-Morales et al.
Samir A Bello et al.
Glycogen synthase kinase-3 (GSK-3) inhibitors are a diverse class of small molecules known to promote osteogenic differentiation in cell monolayers. However, the osteoinductive capacity of GSK-3 inhibitors loaded into scaffolds remains unde...
Nano-dicalcium silicate promotes angiogenesis via enhancing endothelial cell proliferation, migration and tube formation [0.03%]
纳米级二钙硅酸盐通过增强内皮细胞增殖、迁移和管状结构形成来促进血管生成
Ruolan Wang,Yuntao Lin,Yuling Chen et al.
Ruolan Wang et al.
Bone defects, especially critical-sized ones, pose a significant challenge in clinical orthopedics due to their impaired self-regeneration ability. Our previous experiments have confirmed that dicalcium silicate nanoparticles(nC2S) exhibit ...