Synergistic effects of denosumab and BMP-2 on bone regeneration in critical-sized femoral defects in ovariectomized rats [0.03%]
雌激素缺乏动物模型大缺损股骨段骨缺损中denosumab与BMP-2的协同效应研究
ZhouShan Tao,WenJing Cheng,Lin Wang et al.
ZhouShan Tao et al.
Osteoporotic bone defects pose significant clinical challenges due to poor natural repair capacity. Denosumab (DNB) strongly inhibits osteoclast activity, while Bone morphogenetic protein-2 (BMP-2) effectively promotes bone formation; howev...
Natural 2-phenyl chroman flavonoids against Streptococcus mutans: prospects of herbal remedies for dental caries [0.03%]
针对变异链球菌的天然茋类黄酮化合物：中草药防龋潜力研究
Priyabrata Pattanayak,Ananya Pradhan,Sudhansu Sekhar Rout et al.
Priyabrata Pattanayak et al.
Dental caries is a multi-factorial oral infectious disease worldwide. Among the 600 different types of bacteria inhabiting the oral cavity, Streptococcus mutans is considered the most prolific colonizer contributing to dental caries. Althou...
Multi-hierarchical biofunctional polymeric biomaterial to promote wound closure [0.03%]
一种促进伤口闭合的多层次生物功能高分子生物材料
Zacharie Deruyver,Naïma Ahmed Omar,Claire de Lartigue et al.
Zacharie Deruyver et al.
Chronic wounds constitute a significant medical, societal, and economic issue due to the significant delay in wound closure, leading to the increased risk of infection, which extends patients' time spent in the hospital and negatively impac...
Matilde Ciprandi,Veronica Fontanini,Patrizia Sommi et al.
Matilde Ciprandi et al.
Implantable biomaterials for local drug release have been investigated to avoid the ned to cross the blood-brain barrier, which is one of the major limitations of current brain tumors therapies. However, their translation is still limited b...
Engineered membrane-coated nanoparticles enhance ferroptosis and microtubule inhibition in prostate cancer [0.03%]
涂层膜的工程纳米颗粒可增强前列腺癌中铁死亡和微管抑制作用
Kunmu Yang,Yingwei Wang,Chuan Guo et al.
Kunmu Yang et al.
Prostate cancer (PCa), characterized by its high incidence and progression to treatment-resistant stages, remains a major clinical challenge. Herein, we developed a membrane-coated Cabazitaxel (Cab)@TA-Fe³⁺ nanoplatform for enhanced PCa t...
Microwave-assisted synthesis of lithium-bismuth co-doped hydroxyapatite with enhanced antimicrobial and biological performance [0.03%]
微波辅助合成具有增强抗菌和生物性能的锂-铋共掺羟基磷灰石
Oyku Copur,Zafer Evis,Hasan Gocmez et al.
Oyku Copur et al.
Hydroxyapatites (HA) co-doped with Li⁺ and Bi³⁺ ions were synthesized by a microwave-assisted wet precipitation method to improve their structural, biological, and antibacterial performances. Dual doping of Li⁺ and Bi³⁺ ions led to an...
Surface modification of urinary catheters with antibiofilm nanocoating: curcumin modified silver nanoparticles against Proteus mirabilis [0.03%]
用抗菌薄膜纳米涂层对导尿管进行表面改性：姜黄素修饰的银纳米颗粒对抗普罗威登斯菌
N M C Nissanka,K A A Dilhari,G Priyadarshana et al.
N M C Nissanka et al.
Proteus mirabilis is a Gram-negative, uropathogenic bacterium with high virulence due to its crystalline biofilm-forming ability, urease production, and antibiotic resistance. Nanotechnology has emerged as a promising field to address such ...
Resveratrol-loaded chitosan nanoparticles and adipose-derived stem cell-conditioned medium for liver protection against ischemia-reperfusion injury [0.03%]
载白藜芦醇壳聚糖纳米颗粒和脂肪源干细胞条件培养基对肝缺血再灌注损伤的保护作用研究
Longyan Chen,Jianhua Shi,Saman Jalili
Longyan Chen
Ischemia-reperfusion injury (IRI) continues to be a significant obstacle in liver transplantation and often results in graft dysfunction and suboptimal outcomes after transplantation. The current preservation solutions, such as the Universi...
Preparation and application of modified peach gum polysaccharide in the repair of central nervous system injury [0.03%]
改性桃胶多糖的制备及其在中枢神经系统损伤修复中的应用研究
An Wang,Zhangheng Huang,Haoqi Chen et al.
An Wang et al.
Spinal cord injury (SCI) is an irreversible neurological injury that leads to severe motor dysfunction and neurological deficiencies, imposing a large social load. Due to the difficulty of the SCI procedure, the prognosis is normally bad. I...
ADA-GEL composite hydrogel films incorporating mesoporous bioactive glass nanoparticles and silver-doped bioactive glass nanoparticles for biomedical applications [0.03%]
一种用于生物医学应用的ADA-GEL复合水凝胶膜，该膜包含介孔生物活性玻璃纳米粒子和掺银生物活性玻璃纳米粒子
Asimenia Lekidou,Thomas Papatasos,Qaisar Nawaz et al.
Asimenia Lekidou et al.
Hydrogels made from natural polymers are widely used in biomedical engineering as they resemble the extracellular matrix. Alginate dialdehyde-gelatin (ADA-GEL) hydrogels are notable for their biocompatibility, biodegradability, and adjustab...