Strontium-substituted hydroxyapatite nanoparticles as dual-function regulators of osteoblast mineralization and RANKL-induced osteoclastogenesis [0.03%]
具有促进成骨矿化和抗RANKL诱导破骨细胞生成的双重功能的Sr取代羟基磷灰石纳米粒子
Shiao-Wen Tsai,Cheng Li,Shu-Ting Lee et al.
Shiao-Wen Tsai et al.
This study investigated the regulatory effects of strontium-substituted hydroxyapatite (SrHAp) on bone cell regulation, with a specific focus on osteoblast and osteoclast activities. X-ray diffraction verified the successful incorporation o...
A conductive antibacterial composite film containing chopped fibers and ciprofloxacin loaded PCL particles for wound dressing application [0.03%]
一种用于伤口敷料的含切短纤维和环丙沙星载药pcl颗粒的导电抗菌复合膜
Naghmeh Nademi,Pouriya Toloee,Mojdeh Mohseni et al.
Naghmeh Nademi et al.
Designing multifunctional wound dressings with admirable mechanical virtues, appropriate electrical conductivity, and good antibacterial performance is critical for preventing infection and promoting tissue repair. Herein, a conductive gell...
Comparative hemocompatibility assessment of fibrin/heparin-coated and PMEA-coated flow diverters [0.03%]
纤维蛋白/肝素涂层和聚甲基丙烯酸乙二醇酯涂层流体分流器的血液相容性评估比较研究
Huan Wei,Tomáš Riedel,Zuzana Riedelová et al.
Huan Wei et al.
Flow diverters play an important role in the endovascular treatment of intracranial aneurysms; however, their use can be associated with thromboembolic complications. Thus, in recent years, flow diverters with surface coatings have been dev...
Experimental study on the application of a novel degradable calcium-phosphate coated magnesium alloy encircling bone plate in the internal fixation of rib fractures [0.03%]
新型可降解磷酸钙涂层镁合金肋骨环形接骨板内固定的实验研究
Qihong Huang,Ke Chen,Xuhui Liu et al.
Qihong Huang et al.
Severe rib fractures often require surgical plate fixation, but non-biodegradable implants typically necessitate a second surgery for removal. Although AZ31 magnesium alloy is a biodegradable medical material, its excessively rapid in vivo ...
Microstructural evolution and surface property enhancement of H13 tool steel via TIG-based surface alloying under argon and nitrogen atmospheres for biomedical tooling applications [0.03%]
用于生物医学工具的TIG基表面合金化H13模具钢的微观结构演化和表面性能优化
Mahshid Mandani,Mohammad Javanbakht,Abolfazl Mirani
Mahshid Mandani
Surface melting and alloying of H13 tool steel were investigated using the tungsten inert gas (TIG) process under argon and argon-nitrogen shielding atmospheres. The influence of key process parameters, including current intensity and shiel...
Adaptation of mesenchymal stromal cells to culture on collagen-based bioscaffold [0.03%]
基于胶原的生物支架上间充质基质细胞培养适应性的研究
Huan Ting Ong,Dulce B Vargas-Landin,Sharon L Redmond et al.
Huan Ting Ong et al.
Decellularized tissue scaffolds may provide a substrate for cell delivery, yet their impact on stem cell function remains unclear. We evaluated a decellularized pericardium bioscaffold (CardioCel®) as a platform for mesenchymal stromal cel...
Advanced heat-assisted flexible forming of perforated AZ31B magnesium alloy: a hybrid experimental-numerical study for high-precision biocompatible cranial implant fabrication [0.03%]
一种先进的加热辅助成型工艺及其在高精度生物相容性颅骨植入物制造中的应用研究：以开孔AZ31B镁合金为对象的实验与仿真联合研究
Sudarshan Choudhary,Rahul Gurpude,Amrut Mulay
Sudarshan Choudhary
Single Point Incremental Forming (SPIF) is widely recognised as a flexible manufacturing process for producing complex sheet metal components, particularly in small-batch and customised applications. Magnesium alloy known as a lightweight o...
Synergistic effects of erythropoietin and selenium enhance bone regeneration in ovariectomized rats [0.03%]
重组人促红细胞生成素联合硒协同促进卵巢切除雌鼠骨再生的作用及机制探讨
ChangJin Cheng,HaiSheng Wang,WenJing Cheng et al.
ChangJin Cheng et al.
Osteoporotic bone defects present formidable clinical challenges due to the limited capacity for natural bone repair. Erythropoietin (EPO) and Selenium (Se) have both demonstrated significant efficacy in enhancing bone regeneration; however...
Enzyme-responsive release of Insulin-like Growth Factor-1 from recombinant spider-silk protein nanofibrous membrane for enhanced neural cell proliferation [0.03%]
基于重组蜘蛛丝蛋白纳米纤维膜的胰岛素样生长因子-1酶响应释放及其促神经细胞增殖效应
Wubin Yuan,Fengfang Wu,Fanrui Fu et al.
Wubin Yuan et al.
The application of biomaterial scaffolds capable of controllable growth factor release plays a pivotal role in nerve tissue repair. In this study, a recombinant fusion protein RSSP@IGF was designed and fabricated, yielding a novel recombina...
Cholesterol-depleting nanozyme amplifies membrane-diffusive ferroptosis for potentiating anti-tumor immunity in colorectal cancer [0.03%]
胆固醇耗尽型纳米酶放大结直肠癌铁死亡膜弥散以增强抗肿瘤免疫反应
Yu Zhao,Ning Cui
Yu Zhao
To overcome limitations of conventional therapies and low immunotherapy response in colorectal cancer, we developed a cholesterol-depleting nanozyme (ChOx@Fe@C-MOF). This platform synergistically induces ferroptosis and anti-tumor immunity ...