Michael J Evans,Lisa A Miller,Dallas M Hyde
Michael J Evans
Thickening of the basement membrane zone (BMZ) is a characteristic feature of airway remodeling in the lungs of asthmatics. However the significance of a thickened BMZ in the pathology of the asthmatic airway is not known. In this review we...
Liquid Biopsy as Surrogate to Tissue in Lung Cancer for Molecular Profiling: A Meta-Analysis [0.03%]
液体活检在肺癌分子分型中代替组织的作用的 meta 分析
Mona Mlika,Chadli Dziri,Mohamed Majdi Zorgati et al.
Mona Mlika et al.
Background: The accurate microscopic diagnosis of lung cancer has become insufficient due to the concept of personalized medicine. Tissue samples are used not only for microscopic diagnosis but also for the assessment of ...
Choline Triggers Exacerbations of Chronic Obstructive Pulmonary Disease in Patients Infected with Pseudomonas aeruginosa [0.03%]
铜绿假单胞菌感染的慢性阻塞性肺病患者的胆碱加重症状
Sandra Grumelli
Sandra Grumelli
Background: Although exacerbations of chronic obstructive pulmonary disease produced by Pseudomonas aeruginosa infections are a major cause of death, the molecular mechanism that produces them is not well known. Here we f...
Amelia Licari,Riccardo Castagnoli,Elisa Panfili et al.
Amelia Licari et al.
Anti-IgE treatment represents a major breakthrough in the therapeutic management of severe allergic asthma. Omalizumab is the unique biologic treatment registered for asthma therapy in children. The clinical efficacy and safety of omalizuma...
Omalizumab in Children with Severe Allergic Asthma: The Italian Real-Life Experience [0.03%]
奥马珠单抗治疗重度过敏性哮喘患儿的意大利真实世界经验
Amelia Licari,Riccardo Castagnoli,Chiara Denicolò et al.
Amelia Licari et al.
Background: Anti-IgE treatment represents a major breakthrough in the therapeutic management of severe allergic asthma. To date, omalizumab is the only biological drug currently licensed as add-on therapy in children aged...
Fibrocytes in the Pathogenesis of Chronic Fibrotic Lung Disease [0.03%]
肺纤维化疾病发病机制中的成纤维细胞样细胞功能及作用研究进展
Hillary Loomis-King,Bethany B Moore
Hillary Loomis-King
Fibrocytes were initially described in 1999 and since that time there has been a growing body of literature to suggest their importance in a number of chronic lung diseases. It is now well established that fibrocytes derive from the bone ma...
Bethany B Moore,Victor J Thannickal,Galen B Toews
Bethany B Moore
Progressive pulmonary fibrosis is characterized by failed alveolar reepithelialization and fibroblast/myofibroblast accumulation, with deposition of extracellular matrix. This results in loss of lung elasticity, alveolar collapse and fibros...
Matthew R Lammi,Robert P Baughman,Surinder S Birring et al.
Matthew R Lammi et al.
The chronic fibrosing idiopathic interstitial pneumonias (IIPs) are a group of heterogeneous pulmonary parenchymal disorders described by radiologic and histological patterns termed usual interstitial pneumonia (UIP) and non-specific inters...
Patient Perspectives in OMERACT Provide an Anchor for Future Metric Development and Improved Approaches to Healthcare Delivery in Connective Tissue Disease Related Interstitial Lung Disease (CTD-ILD) [0.03%]
OMERACT患者视角在硬皮病肾危象中的作用为连接组织疾病相关间质性肺疾病的未来指标发展和改善医疗保健方法提供了依据（CTD-ILD）
Shikha Mittoo,Sid Frankel,Daphne LeSage et al.
Shikha Mittoo et al.
Objective: The impact and natural history of connective tissue disease related interstitial lung disease (CTD-ILD) are poorly understood; and have not been previously described from the patient's perspective. This investi...
Marcia Campillo-Navarro,Alma D Chávez-Blanco,Isabel Wong-Baeza et al.
Marcia Campillo-Navarro et al.
Lungs are indispensable organs for the respiratory process, and maintaining their homeostasis is essential for human health and survival. However, during the lifetime of an individual, the lungs suffer countless insults that put at risk the...