Guest editorial: Social determinants of health in the psychosis spectrum [0.03%]
精神病光谱中的健康社会决定因素特邀编辑评论文章
Dilip V Jeste,Michael F Green
Dilip V Jeste
Exploring hippocampal dysfunction in schizophrenia with pluripotent stem cell models [0.03%]
利用多能干细胞模型探索精神分裂症海马功能障碍
Deepak Kaji
Deepak Kaji
Schizophrenia is a complex neurodevelopmental disorder characterized by widespread cognitive and behavioral impairments, with the hippocampus playing a critical role in its pathophysiology. While traditional approaches such as animal models...
Impaired recognition of neutral faces in schizophrenia is linked to hostile attribution bias and paranoia [0.03%]
精神分裂症患者对中性面孔识别受损与敌意归因偏差和偏执有关
Aslıhan İmamoğlu,David L Penn,Philip D Harvey et al.
Aslıhan İmamoğlu et al.
Subfield-specific hippocampal microstructural alterations in schizophrenia: A high-resolution DTI study [0.03%]
精神分裂症患者亚区域特异性的海马微结构改变：一种高分辨率弥散张量成像研究
Kunxuan Wang,Yuan Sun,Chao Xia et al.
Kunxuan Wang et al.
Background: Subfield-specific microstructural alterations of the hippocampus and their clinical relevance remain poorly characterized. This study investigated hippocampal subfield-specific microstructural alterations in s...
Disorganization and disintegration in schizophrenia: Metacognitive capacity across levels of conceptual disorganization [0.03%]
精神分裂症中的思维紊乱和整合障碍：不同概念化思维紊乱水平下的元认知能力
Evan J Myers,Paul H Lysaker,Kevin L Rand et al.
Evan J Myers et al.
Disorganized speech can disrupt effective communication in schizophrenia-spectrum disorders (SSDs). Recent work has tied disorganized speech to deficits in metacognitive capacity, or one's capacity to integrate experiences to form complex m...
Dysregulation of miR-335-5p, miR-30d-5p, and miR-744-5p in extracellular vesicles from first-episode psychosis patients: Implications for biomarker discovery [0.03%]
首次精神病发作患者外泌体中miR-335-5p、miR-30d-5p和miR-744-5p失调：作为生物标志物发现的启示
Gabriela Xavier,Vanessa Ota,Gustavo Satoru Kajitani et al.
Gabriela Xavier et al.
First-episode psychosis (FEP) represents a critical period characterized by severe psychotic symptoms, where early intervention is vital. Identifying objective biomarkers to assess symptoms and guide treatment remains a significant challeng...
Cannabidiol attenuates behavioral and electrophysiological changes in the MAM model of schizophrenia in male and female rats [0.03%]
cannabidiol可减轻MAM诱导的大鼠母体模型中的精神分裂症的行为和电生理学变化
Débora Fabris,Lídia M Andrade,Ícaro Silva Freitas et al.
Débora Fabris et al.
Schizophrenia (SCZ) is a neurodevelopmental psychiatric disorder that typically emerges in late adolescence or early adulthood. In rats, administration of the DNA-alkylating agent methylazoxymethanol acetate (MAM) on gestational day (GD) 17...
Machine learning and graph-based connectivity metrics identify language disruption in psychosis: Novel insights from dream reports in an Italian cohort [0.03%]
机器学习和图论连接性指标识别精神病的语言交流障碍：意大利队列梦境报告的新见解
Elena Camon,Stefano Masier,Natália Bezerra Mota et al.
Elena Camon et al.
Language disorganization is a hallmark of psychosis which has traditionally been assessed through clinical interviews and standardized scales. Recent advances in Natural Language Processing (NLP) and graph theory provide innovative, objecti...
Temperament mediates the relationship between family environment and psychotic-like experiences in early adolescence: Findings from the ABCD study [0.03%]
气质在家庭环境和青春期前期精神障碍类似体验之间的关系中起到调解作用：来自ABCD研究的结果
Alexander J Thompson,Riana Marie,Bruce Tonge et al.
Alexander J Thompson et al.
Background: Psychotic-Like Experiences (PLEs) during early adolescence may precede development of later psychotic disorders. Given evidence of environmental challenges contributing to the psychotic disorder psychopatholog...
Cerebellar-cortical dysfunction and schizophrenia: Advances in neurocognition and therapeutic strategies [0.03%]
小脑-皮层功能障碍与精神分裂症：神经认知和治疗策略的新进展
Tinglan Ji,Boxin Yu,Rui Ma
Tinglan Ji
Schizophrenia imposes a global health burden characterized by treatment-refractory cognitive deficits, with converging evidence implicating cerebellar-cortical circuit dysfunction as a pivotal pathophysiological mechanism. In this review, w...