Hélène Verdoux,Peter Schulte,Alexis Lepetit et al.
Hélène Verdoux et al.
Objectives: The safety profile of clozapine raises specific questions regarding risk and management of cancer. We aimed to synthesize the information on cancer in clozapine users relevant for clinical practice. ...
Benson S Ku,Ella J Arrant,Elaine F Walker
Benson S Ku
Trajectories of crystallized cognition over 28 years: Testing the neurodegenerative hypothesis of schizophrenia [0.03%]
Kevin Hazelton,Alexandra Stein,Marcela Gallardo et al.
Kevin Hazelton et al.
Introduction: Cognitive impairment is common among individuals with schizophrenia. However, it is unclear whether these impairments reflect perturbed neurodevelopmental or neurodegenerative processes. While crystallized c...
A high-resolution plasma proteomic framework for stratifying treatment resistance and ultra-resistance in schizophrenia [0.03%]
Caio Andrade de Oliveira,Michelle Verde Ramo Soares,Carolina Saraiva Nunes de Pinho et al.
Caio Andrade de Oliveira et al.
Biological mechanisms underlying heterogeneous antipsychotic response in schizophrenia remain incompletely understood. In this exploratory cross-sectional study, we applied deep data-independent acquisition LC-MS/MS plasma proteomics to 56 ...
Intellectual functioning and personal recovery in individuals with schizophrenia spectrum disorder [0.03%]
M H H Antens,A M Kamperman,B C van Aken et al.
M H H Antens et al.
Background: Individuals with mild intellectual disability or borderline intellectual functioning (MID/BIF) and schizophrenia spectrum disorder (SSD) may encounter unique challenges that can hinder their personal recovery....
Julica Wijnruit,Kasper Voorhout,Vincent Lumsden et al.
Julica Wijnruit et al.
A multimodal fNIRS-based machine learning model for symptom assessment and treatment response prediction in schizophrenia [0.03%]
Lei Cheng,Xiaolu Xu,Haosheng Yang et al.
Lei Cheng et al.
Objective: Predicting early symptom severity and treatment response in schizophrenia is crucial for selecting optimal therapeutic strategies. This study aimed to develop machine learning (ML) models utilizing functional n...
Cross-disorder brain morphological similarity in schizophrenia: Associations with symptom severity and treatment outcome [0.03%]
精神分裂症的跨障碍脑形态相似性：与症状严重程度和治疗效果的关系
Yongbin Wei,Yanmeng Huang,Huiru Cui et al.
Yongbin Wei et al.
Background: Schizophrenia (SCZ) exhibits considerable overlap with other psychiatric disorders in clinical symptoms and brain structural abnormalities, yet the relationship between these shared neuroanatomical patterns an...
Effects of Xanomeline and Trospium Chloride for Negative Symptoms Associated With Physical Activity in Younger and Older Adults with Schizophrenia: Results From a 52-Week, Open-label Clinical Trial [0.03%]
异恶茅林和氯特罗米튬对改善精神分裂症年轻成人和老年患者运动障碍相关阴性症状的影响：一项为期52周开放标签临床试验结果
Philip D Harvey,Inder Kaul,Soumya Chataverdi et al.
Philip D Harvey et al.
Background: Negative symptoms may worsen with age in schizophrenia. Behavioral manifestations of avolition include reduced physical activity, suggesting a linkage with sedentary behavior. We used active and passive digita...
Task-based fNIRS biomarkers of HD-tDCS treatment for negative symptoms in schizophrenia [0.03%]
基于任务的fNIRS生物标志物可表征经颅直流电刺激治疗精神分裂症阴性症状的效果
Ching-En Lin,Li-Fen Chen,Alexander T Sack et al.
Ching-En Lin et al.
Background: Negative symptoms of schizophrenia are highly disabling and remain insufficiently responsive to pharmacological treatment. High-definition transcranial direct current stimulation (HD-tDCS) targeting the left d...