Marko Vitas,Andrej Dobovišek
Marko Vitas
The origin of translation is critical for understanding the evolution of life, including the origins of life. The canonical genetic code is one of the most dominant aspects of life on this planet, while the origin of heredity is one of the ...
Wanyun Shu,Yongfei Yu,Su Chen et al.
Wanyun Shu et al.
The Ser-His dipeptide is the shortest active peptide. This dipeptide not only hydrolyzes proteins and DNA but also catalyzes the formation of peptides and phosphodiester bonds. As a potential candidate for the prototype of modern hydrolase,...
Alexandra Whicher,Eloi Camprubi,Silvana Pinna et al.
Alexandra Whicher et al.
Metabolism is primed through the formation of thioesters via acetyl CoA and the phosphorylation of substrates by ATP. Prebiotic equivalents such as methyl thioacetate and acetyl phosphate have been proposed to catalyse analogous reactions a...
Salinity Effects on the Adsorption of Nucleic Acid Compounds on Na-Montmorillonite: a Prebiotic Chemistry Experiment [0.03%]
盐度对钠蒙脱石表面核酸化合物吸附影响的前生命化学实验研究
Saúl A Villafañe-Barajas,João Paulo T Baú,María Colín-García et al.
Saúl A Villafañe-Barajas et al.
Any proposed model of Earth's primitive environments requires a combination of geochemical variables. Many experiments are prepared in aqueous solutions and in the presence of minerals. However, most sorption experiments are performed in di...
Miryam Palacios-Pérez,Fernando Andrade-Díaz,Marco V José
Miryam Palacios-Pérez
Herein we outline a plausible proteome, encoded by assuming a primeval RNY genetic code. We unveil the primeval phenotype by using only the RNA genotype; it means that we recovered the most ancestral proteome, mostly made of the 8 amino aci...
Chiral Symmetry Breaking in Peptide Systems During Formation of Life on Earth [0.03%]
地球生命起源过程中肽系统中的手性对称性破缺
Konstantin K Konstantinov,Alisa F Konstantinova
Konstantin K Konstantinov
Chiral symmetry breaking in complex chemical systems with a large number of amino acids and a large number of similar reactions was considered. It was shown that effective averaging over similar reaction channels may result in very weak eff...
Phenotypic Graphs and Evolution Unfold the Standard Genetic Code as the Optimal [0.03%]
表型图和进化展开标准基因密码作为最优的
Gabriel S Zamudio,Marco V José
Gabriel S Zamudio
In this work, we explicitly consider the evolution of the Standard Genetic Code (SGC) by assuming two evolutionary stages, to wit, the primeval RNY code and two intermediate codes in between. We used network theory and graph theory to measu...
Satoshi Inaba
Satoshi Inaba
Formaldehyde is abundant in the universe and one of the fundamental molecules for life. Hydrothermal vents produce a substantial amount of hydrogen molecules by serpentinization and promote reductive reactions of single carbon compounds. Th...
Publication of Abstracts and Full Papers from the International Conference on the Origin of Life, San Diego, 2017 [0.03%]
第二届国际生命起源大会摘要集与全文集（美国圣迭戈，2017）
Alan W Schwartz
Alan W Schwartz
Amorphous Silica-Promoted Lysine Dimerization: a Thermodynamic Prediction [0.03%]
无定形二氧化硅促进的赖氨酸二聚化：热力学预测
Norio Kitadai,Kumiko Nishiuchi,Akari Nishii et al.
Norio Kitadai et al.
It has long been suggested that mineral surfaces played a crucial role in the abiotic polymerization of amino acids that preceded the origin of life. Nevertheless, it remains unclear where the prebiotic process took place on the primitive E...