On A Hypothetical Mechanism of Interstellar Life Transfer Trough Nomadic Objects [0.03%]
星际生命迁徙的假说机制及其在游荡天体中的传输效应
Grzegorz Sadlok
Grzegorz Sadlok
Lethal radiation, low vacuum pressure and low temperatures - this is how space welcomes organisms. Crossing of immense interstellar distances inflates the exposure time of biological material to harmful space conditions. This paper discusse...
Reactivity of Metabolic Intermediates and Cofactor Stability under Model Early Earth Conditions [0.03%]
模拟原始地球条件下代谢中间产物的反应性和辅因子的稳定性
Thora R Maltais,David VanderVelde,Douglas E LaRowe et al.
Thora R Maltais et al.
Understanding the emergence of metabolic pathways is key to unraveling the factors that promoted the origin of life. One popular view is that protein cofactors acted as catalysts prior to the evolution of the protein enzymes with which they...
Membranes Composed of Lipopeptides and Liponucleobases Inspired Protolife Evolution [0.03%]
灵感源自原生命演化的脂基肽和核酸膜研究
Gordon D Sproul
Gordon D Sproul
Amino acids and peptides have been demonstrated to form lipoamino acids and lipopeptides under presumed prebiotic conditions, and readily form liposomes. Of the common nucleobases, adenine forms a liponucleobase even below 100 °C. Adenine ...
Carbonyl Sulfide as a Prebiotic Activation Agent for Stereo- and Sequence-Selective, Amyloid-Templated Peptide Elongation [0.03%]
硫化羰作为前生命激活剂选择性延长肽序列及构象的淀粉样模板机制研究
Radoslaw Bomba,Saroj K Rout,Matthias Bütikofer et al.
Radoslaw Bomba et al.
Prebiotic chemical replication is a commonly assumed precursor to and prerequisite for life and as such is the one of the goals of our research. We have previously reported on the role that short peptide amyloids could have played in a temp...
Arthur L Weber,Andro C Rios
Arthur L Weber
The chemistry of imidazolium-catalyzed imidazolium synthesis was studied as part of an effort to develop a plausible prebiotic synthesis of a small catalytic molecule capable of catalyzing its own synthesis. Specifically, we investigated th...
Zhao Li,Li Li,Kristin R McKenna et al.
Zhao Li et al.
The prebiotic origin of polysaccharides, the largest class of biopolymers by mass in extant biology, has seldom been investigated experimentally. Herein, we report on the acid-catalyzed condensation of aqueous solutions of glucose, a model ...
Spontaneous Resolution and Super-coiling in Xerogels of the Products of Photo-Induced Formose Reaction [0.03%]
光诱导福尔马特反应产物气凝胶的自旋和超螺旋现象
Sergey V Stovbun,Anatoly M Zanin,Mikhail V Shashkov et al.
Sergey V Stovbun et al.
This work addresses the supramolecular self-organization in the xerogels of formose reaction products. The UV-induced formose reaction was held in over-saturated formaldehyde solutions at 70∘C without a catalyst. The solutions of the obtai...
Synthesis of Nucleic Acid Bases by Metal Ferrite Nanoparticles from a Single Carbon Atom Precursor Molecule: Formamide [0.03%]
由单一碳原子前体分子甲酰胺合成核碱基：金属铁氧体纳米粒子的作用
Mohammad Asif Iqubal,Rachana Sharma,Kamaluddin et al.
Mohammad Asif Iqubal et al.
The synthesis of prebiotic molecules from simple precursors is believed to be a crucial scheme in order to study the origin of life processes. The present study describes the one-pot synthesis of purine and pyrimidine nucleic acid bases in ...
Hidden Concepts in the History and Philosophy of Origins-of-Life Studies: a Workshop Report [0.03%]
起源研究历史与哲学中的隐含概念：研讨会报告
Carlos Mariscal,Ana Barahona,Nathanael Aubert-Kato et al.
Carlos Mariscal et al.
In this review, we describe some of the central philosophical issues facing origins-of-life research and provide a targeted history of the developments that have led to the multidisciplinary field of origins-of-life studies. We outline thes...
Interactions of Amino Acids and Aminoxazole Derivatives: Cocrystal Formation and Prebiotic Implications Enabled by Computational Analysis [0.03%]
氨基酸与氨基唑衍生物的相互作用：计算分析指导的共晶体形成及前生命意义研究
Nieves Lavado,Juan García de la Concepción,Reyes Babiano et al.
Nieves Lavado et al.
In line with the postulated intermediacy of aminoxazoles derived from small sugars toward the direct assembly of nucleoside precursors, we show here a potential prebiotic scenario where aminoxazolines might have also played further roles as...