Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: final overall survival results from SOLAR-1 [0.03%]
对于PIK3CA突变、激素受体阳性、人表皮生长因子受体2阴性的晚期乳腺癌，阿培利塞联合氟维司群的总生存期最终结果：SOLAR-1研究
F André,E M Ciruelos,D Juric et al.
F André et al.
Background: Activation of the phosphatidylinositol-3-kinase (PI3K) pathway via PIK3CA mutations occurs in 28%-46% of hormone receptor-positive (HR+), human epidermal growth factor receptor-2-negative (HER2-) advanced brea...
Olaparib monotherapy as primary treatment in unselected triple negative breast cancer [0.03%]
奥拉帕利单药治疗未经选择的三阴性乳腺癌作为一线治疗
H P Eikesdal,S Yndestad,A Elzawahry et al.
H P Eikesdal et al.
Background: The antitumor efficacy of PARP inhibitors (PARPi) for breast cancer patients harboring germline BRCA1/2 (gBRCA1/2) mutations is well established. While PARPi monotherapy was ineffective in patients with metast...
Reply to the Letter to the Editor "Androgen deprivation therapy may constitute a more effective prophylactic than therapeutic strategy in COVID-19 patients" by N. Bennani and I. M. Bennani-Baiti [0.03%]
纳比勒·本纳尼和伊娃·马尔特·本纳尼-拜泰发表的题为“雄激素剥夺治疗可能是COVID-19患者的预防性策略而不是治疗性策略”的信件的回复
S Zumerle,M Montopoli,M Rugge et al.
S Zumerle et al.
Genetic and hormonal influence on SARS-CoV-2-infection susceptibility: Re: The potential influence of human Y-chromosome haplogroup on COVID-19 prevalence and mortality [0.03%]
关于Y染色体基因组多态性对新冠肺炎流行和病死率潜在影响的遗传及激素作用：来信回复
M Montopoli,S Zumerle,M Rugge et al.
M Montopoli et al.
Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up [0.03%]
口腔、喉部、口咽及下咽鳞状细胞癌：诊断、治疗和随访的EHNS-ESMO-ESTRO临床实践指南
J-P Machiels,C René Leemans,W Golusinski et al.
J-P Machiels et al.
Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival [0.03%]
新辅助治疗后的乳腺癌患者循环肿瘤DNA反映疗效和预后
M J M Magbanua,L B Swigart,H-T Wu et al.
M J M Magbanua et al.
Background: Pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) is strongly associated with favorable outcome. We examined the utility of serial circulating tumor DNA (ctDNA) testing for predicting pCR an...
Adjuvant chemotherapy is superior to chemoradiation after D2 surgery for gastric cancer in the per-protocol analysis of the randomized CRITICS trial [0.03%]
CRITICS随机试验的意向性分析显示,D2术后辅助化疗优于放化疗
W O de Steur,R M van Amelsfoort,H H Hartgrink et al.
W O de Steur et al.
Background: The Intergroup 0116 and the MAGIC trials changed clinical practice for resectable gastric cancer in the Western world. In these trials, overall survival improved with post-operative chemoradiotherapy (CRT) and...
Myelodysplastic syndromes: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†☆ [0.03%]
低恶性骨髓疾病：诊断、治疗及随访的ESMO临床实践指南
P Fenaux,D Haase,V Santini et al.
P Fenaux et al.