Quality by design-based development of thermoresponsive injectable depots for sustained analgesic delivery [0.03%]
基于质量的设计开发热响应性注射 depot 以实现持续的镇痛输送
Dakshinesh Parameswaran,Suriya Prakaash Kannan,Damodharan Narayanasamy
Dakshinesh Parameswaran
The use of thermoresponsive injectable depots that undergo in situ sol-gel transition at physiological temperature represents an attractive strategy for sustained parenteral drug delivery. In the present study, a thermoresponsive injectable...
Bi-layered polycarbonate urethane/alginate di-aldehyde crosslinked gelatin membrane as a potential biomaterial for wound healing applications [0.03%]
用于伤口愈合的双层聚碳酸酯尿烷/海藻酸二醛交联明胶膜生物材料
Prathyusha,Resmi Rajalekshmi,Saravana Perumal Ramakrishna et al.
Prathyusha et al.
Diabetic wounds, particularly foot ulcers, represent a major healthcare burden worldwide due to prolonged inflammation, reduced cellular migration and impaired tissue repair due to hyperglycemia. To treat a wound as quickly and effectively,...
Development and characterization of core-shell nanofiber wound dressings containing Nigella Sativa and Laurus Nobilis essential oils via coaxial electrospinning [0.03%]
采用同轴静电纺丝技术制备并表征含有鼠尾草和 laurel精油的核壳纳米纤维伤口敷料
Fatih Mehmet Eynur,Gülcan Ayşin Karaca,Alpay Köse et al.
Fatih Mehmet Eynur et al.
The demand for functional wound dressings for the effective management of acute and chronic wounds is increasing. The composition of functional components such as polymers and essential oils enables the development of wound dressings. In th...
Oxidative-stress-responsive polymeric nanocarriers for Alzheimer's disease: emerging antioxidant strategies using NAC and curcumin [0.03%]
用于阿尔茨海默病的氧化应激响应型聚合物纳米载体：使用NAC和姜黄素的新兴抗氧化策略
Lalit Kumar Singh,Satya Prakash Singh,Pankaj Sharma
Lalit Kumar Singh
A complex combination of oxidative stress, mitochondrial dysfunction, neuroinflammation, and protein aggregation initiates Alzheimer disease (AD), and redox imbalance becomes an initial and lead pathological process. Traditional antioxidant...
Properties of chitosan-gelatine based, aloe vera and propolis added biofunctional wound dressing material [0.03%]
基于壳聚糖-明胶并添加了芦荟和蜂胶的生物功能伤口敷料材料的性质研究
Haya Akkad,Fatih Ciftci,Azime Erarslan et al.
Haya Akkad et al.
This study describes the development and characterization of a multilayered wound dressing composed of a chitosan (CHI), gelatin (GEL), and Aloe vera (AV) base layer integrated with electrospun polyvinyl alcohol (PVA)/propolis nanofibers (W...
Nanotoxicology meets smart polymers: advancing safety-by-design nanomaterials [0.03%]
纳米毒理学与智能聚合物相遇：推进“设计安全”的纳米材料
Gaurav Tiwari,Ruchi Tiwari,Anand Badrivishal Mundada et al.
Gaurav Tiwari et al.
Smart polymers have played great role in enhancing nanomedical application areas in drug delivery, diagnosis and environment sensitive treatment systems. Nonetheless, their highly adaptive and structurally diverse nature leads to more conce...
Bilayered dissolving microneedles for microemulsion-mediated ocular delivery of brimonidine tartrate in glaucoma therapy [0.03%]
双层可溶性微针递送溴莫尼定滴眼液治疗青光眼
Nisha Rajbhar,Harsh P Nijhawan,Khushwant S Yadav
Nisha Rajbhar
Glaucoma remains a leading cause of irreversible blindness worldwide, primarily driven by progressive optic nerve degeneration associated with elevated intraocular pressure (IOP). Conventional brimonidine tartrate (BRT) eye drops suffer fro...
Chitosan-based bioactive polymer systems for the treatment of vulvovaginitis: advances in vaginal drug delivery [0.03%]
用于治疗外阴阴道炎的壳聚糖基生物活性聚合物系统：阴道药物递送技术的新进展
Riya Patel,Shivani Patel,Omar Awad Alsaidan et al.
Riya Patel et al.
Vulvovaginitis is an inflammation of the vulva and vagina that is commonly caused by yeast infections, bacterial vaginosis, or sexually transmitted illnesses affecting approximately 70-75% of women at least once during their lifetime, with ...
Synthesis and characterization of novel PVA/walnut shell-based composite films: a potential for biomedical applications [0.03%]
新型PVA/核桃壳基复合膜的制备及表征：一种生物医学应用的潜在材料
Maiser Mehraj,Omar Hussain,Mohammad Arif Parray
Maiser Mehraj
Novel bioactive composite films based on polyvinyl alcohol (PVA) reinforced with walnut shell powder (WSP) and medicinal plant additives - Lawsonia inermis, Nepeta cataria, and Artemisia vulgaris - were developed using a solution casting me...
Sona Sunil,Arthi Chandramouli,Kavitha Gopal et al.
Sona Sunil et al.
The field of in situ polymer-bioceramic composites represents a novel domain that imparts advancements in bone tissue engineering by its dual angiogenic and osteogenic potential. In this study, we focused on developing an in-situ synthesise...