Mucoadhesive amphiphilic polymers for buccal drug delivery: overcoming solubility and permeation barriers [0.03%]
用于颊部药物输送的黏膜粘附两亲性聚合物：克服溶解度和渗透障碍
Avnish Kumar,Gulshan Rathore,Anurag Verma et al.
Avnish Kumar et al.
Buccal drug delivery offers a non-invasive and patient-friendly alternative to conventional oral administration because of its rapid onset of action and capacity to avoid hepatic first-pass metabolism. However, drugs' poor water solubility,...
Platelet-rich plasma integrated stromal vascular fraction gel bioink for 3D bioprinting and skin wound repair [0.03%]
富血小板血浆整合基质血管组分凝胶生物墨水用于三维生物打印和皮肤伤口修复
Tian Jiao,Zhuo Wang,Chaofan Sun et al.
Tian Jiao et al.
The shortage of skin grafts remains a key challenge in the repair of full-thickness skin defects, highlighting the urgent need for suitable 3D-bioprinted skin substitutes. Although various hydrogel bioinks have been developed for skin tissu...
Chitosan-hyaluronic acid engineered polycaprolactone nanoparticles enhance curcumin antiplasmodial activity and preserve blood-brain barrier integrity [0.03%]
壳聚糖透明质酸工程化聚己内酯纳米颗粒增强姜黄素抗疟活性并保持血脑屏障完整性
James Mwajombe,Rami Ahmed,Retsepile E Maphasa et al.
James Mwajombe et al.
Cerebral malaria (CM) is a severe neurological complication of Plasmodium falciparum infection associated with endothelial activation, neuroinflammation, and disruption of the blood-brain barrier (BBB). While curcumin (Cur) possesses antipl...
Synthesis and bio-activities of new chitosan Schiff base derivatives with salicylaldoxime and 3-nitro aniline [0.03%]
含水杨醛肟和硝基苯胺的壳聚糖席夫碱衍生物的合成及活性研究
Sivaranjani P,Ida Malarselv R,Pricilla R et al.
Sivaranjani P et al.
A new chitosan-based Schiff base derivative of CS-3NA was synthesized by condensing chitosan with salicylaldoxime and 3-nitroaniline. The structural resonances were identified using Fourier transform infrared spectroscopy (FTIR), UV,1H, and...
Derivatization and multifunctional applications of gum Arabic: from natural exudate to next-generation biopolymer [0.03%]
角豆胶的改性及多功能应用：从天然树脂到下一代生物聚合物
Rutu Patel,Rucha Khumkar,Vasanti Suvarna
Rutu Patel
Gum Arabic (GA), a natural dried exudate obtained mainly from Acacia senegal and Acacia seyal, is a highly branched polysaccharide-protein complex known for its excellent solubility, biodegradability, and emulsifying properties. Owing to it...
A fabrication method for artificial small-diameter vascular grafts with multi-layer walls: stepwise lyophilization [0.03%]
一种制造人工小直径血管移植物的多层管壁分步冷冻干燥法
Wei Gong,Mingbo Ruan,Jinge Li et al.
Wei Gong et al.
Artificial small-diameter vascular grafts (sdVGs) offer a promising alternative to autologous vessels. However, suboptimal wall architecture and mechanical mismatch can lead to complications. The modular mold-assisted stepwise lyophilizatio...
Development of HPMC-modified starch/ZnO nanocomposite films using biodegradable plasticizers for improved antioxidant, antimicrobial, and cytocompatible characteristics [0.03%]
一种使用可降解增塑剂改善抗氧化、抗菌和细胞相容性的羟丙基甲基纤维素改性淀粉/氧化锌纳米复合膜的研究与发展
Pratikeswar Panda,Debasish Sahoo,Abhinash Senapati et al.
Pratikeswar Panda et al.
Biopolymer-based wound dressings offer a sustainable platform for developing multifunctional films with improved moisture regulation, biocompatibility, and protection against microbial contamination. In this study, nanocomposite films were ...
Rheological characterisation and printability assessment of an optimised bioink for extrusion-based 3D bioprinting [0.03%]
一种用于挤出式3D生物打印的优化生物墨水的流变学表征及可打印性评价
Alice Upton,Athina Mylona,Georgina Zimbitas
Alice Upton
The performance of extrusion-based 3D bioprinting depends critically on the rheology of bioinks, which must balance printability with post-deposition structural fidelity. Here we present a statistically optimised, human-compatible hydrogel ...
Machine learning in tissue engineering: a comprehensive review of applications, challenges, and prospects [0.03%]
组织工程中的机器学习：应用、挑战与前景的全面综述
Itishree Jogamaya Das,Himansu Bhusan Samal,Pritipragatika Nayak et al.
Itishree Jogamaya Das et al.
Tissue engineering, rooted in cell biology and materials science, focuses on repairing or replacing injured tissues and organs, offering groundbreaking solutions in regenerative medicine. Although progress has been made in scaffold design, ...
Tannic acid enhanced silk fibroin/hyaluronic acid hydrogel for In vitro hemostatic and antibacterial wound dressing [0.03%]
用于体外止血和抗菌伤口敷料的单宁酸增强型丝素/透明质酸水凝胶
Liuyuxuan Hao,Maolin Zhang,Disheng Xiao et al.
Liuyuxuan Hao et al.
Natural polymeric hydrogels based on silk fibroin (SF) and hyaluronic acid (HA) offer promising biocompatible platforms for wound dressings, however, their clinical applications are limited by inadequate mechanical strength and a lack of mu...