Curcumin and its analogues in mucopenetrative nano-formulations for cancer therapy: current evidence, challenges, and future directions [0.03%]
用于癌症治疗的姜黄素及其类似物的粘膜渗透型纳米制剂：现有证据、挑战和未来方向
Chahla Imane Rekaibi,Nashiru Billa
Chahla Imane Rekaibi
Cancer remains a leading cause of mortality worldwide, whilst conventional therapy is constrained by severe side effects and drug resistance. Curcumin, derived from turmeric demonstrates anticancer, antioxidant, anti-inflammatory, and antit...
Microalgae-derived polyhydroxyalkanoate/PCL composite nanofiber scaffolds for accelerated wound healing in diabetic rats [0.03%]
微藻聚羟基烷酸酯/PCL复合纳米纤维支架促进糖尿病大鼠伤口加速愈合的研究
Rehab Ali Hussein,Sayeda Mohamed Abdo,Khaled Mahmoud et al.
Rehab Ali Hussein et al.
Diabetes mellitus (DM) is a multifactorial metabolic disorder characterized by chronic hyperglycemia due to impaired insulin secretion and/or action. A severe complication is delayed wound healing, particularly diabetic foot ulcers, associa...
Emerging trends of multifunctional biomaterial scaffolds for targeted antibacterial therapy and enhanced bone regeneration in osteomyelitis [0.03%]
用于骨髓炎的抗菌治疗和增强骨再生的多功能生物材料支架的新兴趋势
Jayesh S Bhamare,Ginpreet Kaur
Jayesh S Bhamare
A biocompatible scaffolds repairs bone defects with anti-infection properties in the treatment of osteomyelitis. Osteomyelitis is a severe infection of bone marrow, caused by Staphylococcus aureus, leading to inflammation and bone destructi...
Microneedle-mediated drug delivery for Parkinson's disease: advances, challenges, and future perspectives [0.03%]
用于帕金森病的微针给药：进展、挑战与未来展望
Sonam M Gandhi,Ashu Tyagi,Satyam Shukla et al.
Sonam M Gandhi et al.
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide, affecting over 8.5 million individuals, with prevalence projected to exceed 12 million by 2040 due to global population aging. The escalating burden...
Chondroitin sulfate and chondroitinase ABC: emerging roles in drug delivery and wound healing applications [0.03%]
硫酸软骨素和ABC螯合酶在药物递送及伤口愈合中的应用研究取得新进展
Bassam M Abualsoud,Majid Alhomrani,Abdulhakeem S Alamri et al.
Bassam M Abualsoud et al.
Chondroitin sulfate (CS), a naturally occurring glycosaminoglycan, is renowned for its biocompatibility, biodegradability, and considerable role in wound healing and drug delivery applications. In wound healing, CS fosters tissue regenerati...
Polydopamine/gelatin layer-by-layer self-assembled polycaprolactone nanofibers loaded with 4-methoxycinnamic acid for wound healing [0.03%]
基于聚己内酯纳米纤维负载4-甲氧基肉桂酸的聚多巴胺/明胶层层自组装技术在伤口修复中的应用研究
Kumar Shivanee,Rajan Kalpana Sahana,Arumugam Bharathraj et al.
Kumar Shivanee et al.
Wound healing is a dynamic and tightly regulated biological phenomenon involving coordinated cellular and molecular events essential for tissue repair and regeneration. Conventional wound dressings possess limited bioactivity, antibacterial...
Advanced drug delivery systems for regenerative medicine: nanobiomaterial innovations, hybrid platforms, and translational perspectives [0.03%]
用于再生医学的先进药物输送系统：纳米生物材料创新、混合平台和转化视角
Sarad Pawar Naik Bukke,Chandrashekar Thalluri,Jharna Medhi et al.
Sarad Pawar Naik Bukke et al.
Regenerative therapies focus on repairing, reproducing, or regenerating tissues and organs that have been harmed due to injury or illness through cellular based therapy and bioactive molecule driven systems. The advancement of this type of ...
Mucoadhesive amphiphilic polymers for buccal drug delivery: overcoming solubility and permeation barriers [0.03%]
用于颊部药物输送的黏膜粘附两亲性聚合物：克服溶解度和渗透障碍
Avnish Kumar,Gulshan Rathore,Anurag Verma et al.
Avnish Kumar et al.
Buccal drug delivery offers a non-invasive and patient-friendly alternative to conventional oral administration because of its rapid onset of action and capacity to avoid hepatic first-pass metabolism. However, drugs' poor water solubility,...
Platelet-rich plasma integrated stromal vascular fraction gel bioink for 3D bioprinting and skin wound repair [0.03%]
富血小板血浆整合基质血管组分凝胶生物墨水用于三维生物打印和皮肤伤口修复
Tian Jiao,Zhuo Wang,Chaofan Sun et al.
Tian Jiao et al.
The shortage of skin grafts remains a key challenge in the repair of full-thickness skin defects, highlighting the urgent need for suitable 3D-bioprinted skin substitutes. Although various hydrogel bioinks have been developed for skin tissu...
Chitosan-hyaluronic acid engineered polycaprolactone nanoparticles enhance curcumin antiplasmodial activity and preserve blood-brain barrier integrity [0.03%]
壳聚糖透明质酸工程化聚己内酯纳米颗粒增强姜黄素抗疟活性并保持血脑屏障完整性
James Mwajombe,Rami Ahmed,Retsepile E Maphasa et al.
James Mwajombe et al.
Cerebral malaria (CM) is a severe neurological complication of Plasmodium falciparum infection associated with endothelial activation, neuroinflammation, and disruption of the blood-brain barrier (BBB). While curcumin (Cur) possesses antipl...