Biodegradable self-gelling powder of quaternized chitin/sodium hyaluronate for rapid hemostasis [0.03%]
季胺化壳聚糖/透明质酸钠生物可降解自凝胶粉体的快速止血性能研究
Kunliang Jiang,Mingzhen Cai,Xulin Jiang
Kunliang Jiang
Rapid and effective hemostasis for unknown bleeding points and irregularly shaped wounds is very important. Here, water-soluble quaternized chitin (QC2) with relatively low hemolysis ratio was synthesized homogeneously in NaOH/urea aqueous ...
Synthesis, characterization and antibacterial activity of tetracycline loaded alginate-based hydrogel for drug delivery and artificial neural network modelling study [0.03%]
基于藻酸盐的四环素载药水凝胶的合成、表征及抗菌活性研究和人工神经网络模型研究
Leila Rezaie Shirmard,Saghi Sepehri,Mahsa Zibanejad Jelodar et al.
Leila Rezaie Shirmard et al.
Chemical and physically crosslinked hydrogels, as pharmaceutical carrier compounds with antibacterial and sustained release features, hold high potential for clinical uses. In this study, synthesized biodegradable tetracycline drug-loaded h...
Bone marrow-derived and adipose-derived stem cells on bacterial nanocellulose-chitosan-gelatin-hydroxyapatite scaffolds for bone tissue engineering [0.03%]
负载骨髓源和脂肪源干细胞的细菌纳米纤维素-壳聚糖-明胶-羟基磷灰石复合支架用于骨组织工程
Phasuwit P Phatchayawat,Supansa Yodmuang,Muenduen Phisalaphong
Phasuwit P Phatchayawat
Bone marrow-derived MSCs (BM-MSCs) and adipose-derived MSCs (AD-MSCs) are both multipotent with therapeutic potential. In this study, a study for bone tissue engineering was performed using both cell types on three-dimensional (3D) bacteria...
Curcumin and its analogues in mucopenetrative nano-formulations for cancer therapy: current evidence, challenges, and future directions [0.03%]
用于癌症治疗的姜黄素及其类似物的粘膜渗透型纳米制剂：现有证据、挑战和未来方向
Chahla Imane Rekaibi,Nashiru Billa
Chahla Imane Rekaibi
Cancer remains a leading cause of mortality worldwide, whilst conventional therapy is constrained by severe side effects and drug resistance. Curcumin, derived from turmeric demonstrates anticancer, antioxidant, anti-inflammatory, and antit...
Microalgae-derived polyhydroxyalkanoate/PCL composite nanofiber scaffolds for accelerated wound healing in diabetic rats [0.03%]
微藻聚羟基烷酸酯/PCL复合纳米纤维支架促进糖尿病大鼠伤口加速愈合的研究
Rehab Ali Hussein,Sayeda Mohamed Abdo,Khaled Mahmoud et al.
Rehab Ali Hussein et al.
Diabetes mellitus (DM) is a multifactorial metabolic disorder characterized by chronic hyperglycemia due to impaired insulin secretion and/or action. A severe complication is delayed wound healing, particularly diabetic foot ulcers, associa...
Emerging trends of multifunctional biomaterial scaffolds for targeted antibacterial therapy and enhanced bone regeneration in osteomyelitis [0.03%]
用于骨髓炎的抗菌治疗和增强骨再生的多功能生物材料支架的新兴趋势
Jayesh S Bhamare,Ginpreet Kaur
Jayesh S Bhamare
A biocompatible scaffolds repairs bone defects with anti-infection properties in the treatment of osteomyelitis. Osteomyelitis is a severe infection of bone marrow, caused by Staphylococcus aureus, leading to inflammation and bone destructi...
Microneedle-mediated drug delivery for Parkinson's disease: advances, challenges, and future perspectives [0.03%]
用于帕金森病的微针给药：进展、挑战与未来展望
Sonam M Gandhi,Ashu Tyagi,Satyam Shukla et al.
Sonam M Gandhi et al.
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide, affecting over 8.5 million individuals, with prevalence projected to exceed 12 million by 2040 due to global population aging. The escalating burden...
Chondroitin sulfate and chondroitinase ABC: emerging roles in drug delivery and wound healing applications [0.03%]
硫酸软骨素和ABC螯合酶在药物递送及伤口愈合中的应用研究取得新进展
Bassam M Abualsoud,Majid Alhomrani,Abdulhakeem S Alamri et al.
Bassam M Abualsoud et al.
Chondroitin sulfate (CS), a naturally occurring glycosaminoglycan, is renowned for its biocompatibility, biodegradability, and considerable role in wound healing and drug delivery applications. In wound healing, CS fosters tissue regenerati...
Polydopamine/gelatin layer-by-layer self-assembled polycaprolactone nanofibers loaded with 4-methoxycinnamic acid for wound healing [0.03%]
基于聚己内酯纳米纤维负载4-甲氧基肉桂酸的聚多巴胺/明胶层层自组装技术在伤口修复中的应用研究
Kumar Shivanee,Rajan Kalpana Sahana,Arumugam Bharathraj et al.
Kumar Shivanee et al.
Wound healing is a dynamic and tightly regulated biological phenomenon involving coordinated cellular and molecular events essential for tissue repair and regeneration. Conventional wound dressings possess limited bioactivity, antibacterial...
Advanced drug delivery systems for regenerative medicine: nanobiomaterial innovations, hybrid platforms, and translational perspectives [0.03%]
用于再生医学的先进药物输送系统：纳米生物材料创新、混合平台和转化视角
Sarad Pawar Naik Bukke,Chandrashekar Thalluri,Jharna Medhi et al.
Sarad Pawar Naik Bukke et al.
Regenerative therapies focus on repairing, reproducing, or regenerating tissues and organs that have been harmed due to injury or illness through cellular based therapy and bioactive molecule driven systems. The advancement of this type of ...